XXXVIII Annual Meeting of the Portuguese Society of Immunology - From Immune Disorders to Immunotherapies

FROM IMMUNE DISORDERS TO IMMUNOTHERAPIES

FINAL PROGRAMME & POSTERS LIST [PDF]

25^th NOVEMBER

18.00h – 19.00h	OPENING KEYNOTE LECTURE
	Maria Rescigno - Italy The mucosal immune barrier in bacterial handling in the gut.

19.00h – 19.30h	Get Together – drinks and snacks


26^th NOVEMBER

09:00 – 11:00	SESSION 1: IMMUNE DEVELOPMENT \| SPONSORED BY IBMC
	Chair: Nuno Alves

	Design principles of adaptive immune systems Thomas Boehm, Max Planck Institute of Immunobiology and Epigenetics, Freiberg, Germany Thymic microenvironmental factors involved in thymocyte malignant transformation Nuno Rodrigues dos Santos, Univ. Algarve, Faro, Portugal

	ORAL COMMUNICATIONS
	Cell-autonomous retinoic acid signaling controls Lymphoid Tissue inducer cell differentiation and lymphoid organ size Manuela Ferreira, IMM - Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Portugal Implications of IL-10 in the development of hematological disorders Ana Matos Cardoso, Life and Health Sciences Research Institute (ICVS) and ICVS/3B’s, Portugal Human γδ thymocytes are functionally immature and require IL-2 signals to differentiate into type 1 cytotoxic lymphocytes Julie C. Ribot, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Portugal


11.00 – 11.30	Coffee-break

11.30 – 13.00	SESSION 2: CANCER IMMUNOTHERAPY \| SPONSORED BY ENZIFARMA
	Chairs: Margarida Lima, Manuel Vilanova and Paula Ferreira

	Idiotype vaccines for lymphoma Maurizio Bendandi, Center for Applied Medical Research, University of Navarra, Pamplona, Spain Gamma-delta T cells within tumors: recruitment, recognition and functions Bruno Silva-Santos, IMM, Lisbon, Portugal

	ORAL COMMUNICATIONS
	Progenitor deprivation provokes acute T cell lymphoblastic leukemia Vera C. Martins, Institute for Immunology, University of Ulm and Division of Cellular Immunology, German Cancer Research Center, Germany Targeting Chronic Lymphocytic Leukemia Cells Viability Using CX-4945, a Clinical-Stage CK2-Specific Inhibitor Leila R. Martins, Instituto de Medicina Molecular, Lisboa, Portugal Understanding the pro-tumour role of γδ T cells in ovarian cancer Margarida Rei, IMM, Lisboa, Portugal; GABBA, Porto, Portugal; Barts and The London School of Medicine, London, UK

13.00 – 14.00	Lunch

14.00 – 15.00	SPI GENERAL ASSEMBLY

15.30 – 17.30	SESSION 3: INFECTION AND VACCINES \| SPONSORED BY ICBAS
	Chairs: Manuel Vilanova and Paula Ferreira

	Mucosal memory T cells: a three-sided coin Leo Lefrançois, University of Connecticut Health Center, Farmington, Connecticut, USA How Leismania infection modify innate immune cells to regulate adaptative immunity Anabela Cordeiro da Silva, IBMC, Porto, Portugal

	ORAL COMMUNICATIONS
	BCG vaccination induced IL-17+TNF+IL-2+ polyfunctional memory T cells correlated with increased protection against M. tuberculosis Andrea Cruz, Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, ICVS/3B’s - PT Government Associate Laboratory, Braga/Guimarães, Portugal Impaired Treg function in mice infected with Candida albicans ?sap456 mutants is associated with attenuated fungal virulence Alexandra Correia, Centre of Molecular and Environmental Biology (CBMA), Biology Department, University of Minho,ICBAS-UP - Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Portugal Deficient production of reactive oxygen species in p47phox/Ncf1 mice impairs memory B cell differentiation and B cell response against Candida albicans Gustavo Rossi, Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal, Universidade Federal do Paraná, Brazil

17.30 – 18.00	Coffee-break

18.00 – 20.00	SESSION 4: ALLERGY \| SPONSORED BY ROCHE
	Chairs: Esmeralda Neves and Emília Faria

	Protective and pathogenic immunological memory Andreas Radbruch,Deutsches Rheuma-Forschungszentrum Berlin (DRFZ) Mechanisms and targets of allergen-specific immunotherapy Luís Delgado, Hospital de S. João, Porto, Portugal

	ORAL COMMUNICATIONS
	Can NOS3 and ACE polymorphisms modulate the immune response in a Portuguese Asthmatic population? Margarida Cortez, CHLN-HSM, Lisbon, Portugal Different impact of regulatory T cells on nematode-induced immune evasion in BALB/c and C57BL/6 mice Birte Blankenhaus, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany Foxp3 expression is required for the induction of therapeutic tissue tolerance Frederico S Regateiro, Sir William Dunn School of Pathology, Oxford University, United Kingdom, Institute of Immunology, Faculty of Medicine, University of Coimbra, Portugal


27^th NOVEMBER

09.00 – 11.00	SESSION 5: IMMUNODEFICIENCY \| SPONSORED BY OCTAPHARMA
	Chairs: Laura Marques and Margarida Guedes

	When T cells fail to function Taco Kuijpers, Academic Medical Center, Amsterdam, The Netherlands CVIDs: beyond B cell deficiency Susana Lopes da Silva, IMM and Hospital Santa Maria, Lisbon, Portugal
	ORAL COMMUNICATIONS
	Clinical and laboratory features of Common Variable Immunodeficiency patients from Centro Hospitalar do Porto David Penas, Master in Medicine by Instituto de Ciências Biomédicas Abel Salazar, Porto, Portugal X-Linked Agammaglobulinemia: 12 years of experience Alexandre Fernandes, Unidade de Infecciologia Pediátrica e Imunodeficiências – Serviço de Pediatria – Centro Hospitalar do Porto, Porto, Portugal How Much does the Human Immunodeficiency Vírus (HIV) infection Increase the Risk of Tuberculosis in Porto? Cláudia Nóbrega, Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, ICVS/3B’s – PT Government Associate Laboratory, Braga/Guimarães, Portugal

11:00 - 11:30	Coffee-break

11.30 – 13.30	SESSION 6: AUTOIMMUNITY \| SPONSORED BY IZASA
	Chair: Carlos Vasconcelos and Júlia Vasconcelos

	The Evolution of Stem Cell Therapy for Autoimmune and Inflammatory Diseases Thomas Daikeler, University of Basel, Switzerland New therapeutic strategies in autoimmune diseases António Marinho, Centro Hospitalar do Porto, Porto, Portugal

	ORAL COMMUNICATIONS
	High-Dose Chemotherapy and Autologous Stem Cell Transplantation in a patient with severe Systemic sclerosis – case report Carlos Pinho Vaz, Serviço de Transplantação de Medula Óssea - IPO Porto Adjuvant can facilitate induction of therapeutic tolerance to recombinant factor VIII in a mouse model of hemophilia Ana Água-Doce, Instituto de Medicina Molecular, Instituto Gulbenkian de Ciência, Oeiras, Portugal Regulatory T-cells, CD25 and IL2RA genetic variation in unaffected relatives of SLE patients Constantin Fesel, Instituto Gulbenkian de Ciência, Oeiras,Portugal

13.30	Closing Session

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