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39}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018761744\&doi=10.1080\%2f13506129.2016.1272452\&partnerID=40\&md5=e849f225289203721c73e62855d9016a}, author = {Gon{\c c}alves, P. and Martins, H. and Costelha, S. and Saraiva, M.J.} } @article {6500, title = {Force spectroscopy reveals the presence of structurally modified dimers in transthyretin amyloid annular oligomers}, journal = {Journal of Molecular Recognition}, volume = {30}, year = {2017}, note = {Cited By :1Export Date: 19 March 2018}, month = {2017}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84996636689\&doi=10.1002\%2fjmr.2587\&partnerID=40\&md5=bc8641bc3db6136a5cfa24146453ca95}, author = {Pires, R.H. and Saraiva, M.J. and Damas, A.M. and Kellermayer, M.S.Z.} } @article {6487, title = {The importance of pre-clinical studies in animal models of TTR amyloidosis for the discovery of novel patient disease biomarkers}, journal = {Amyloid}, volume = {24}, year = {2017}, note = {Export Date: 19 March 2018}, month = {2017}, pages = {83 - 84}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018728032\&doi=10.1080\%2f13506129.2016.1278362\&partnerID=40\&md5=aa06f1bd45c30dc033d5acfe0635ebb0}, author = {Gon{\c c}alves, N.P. and Martins, D. and Saraiva, M.J.} } @article {6373, title = {MMP-14 overexpression correlates with the neurodegenerative process in familial amyloidotic polyneuropathy}, journal = {DMM Disease Models and Mechanisms}, volume = {10}, year = {2017}, note = {Export Date: 19 March 2018}, month = {2017}, pages = {1253 - 1260}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85031771832\&doi=10.1242\%2fdmm.028571\&partnerID=40\&md5=c295488f72e15dd1887eb15a7e701f7f}, author = {Martins, D. and Moreira, J. and Gon{\c c}alves, N.P. and Saraiva, M.J.} } @article {6426, title = {Multimodal imaging Gd-nanoparticles functionalized with Pittsburgh compound B or a nanobody for amyloid plaques targeting}, journal = {Nanomedicine}, volume = {12}, year = {2017}, note = {Cited By :2Export Date: 19 March 2018}, month = {2017}, pages = {1675 - 1687}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85022183682\&doi=10.2217\%2fnnm-2017-0079\&partnerID=40\&md5=e04f17adc10cde37e62ddc4e46694295}, author = {Pansieri, J. and Plissonneau, M. and Stransky-Heilkron, N. and Dumoulin, M. and Heinrich-Balard, L. and Rivory, P. and Morfin, J.-F. and Toth, E. and Saraiva, M.J. and All{\'e}mann, E. and Tillement, O. and Forge, V. and Lux, F. and Marquette, C.} } @article {6698, title = {Curcumin: A multi-Target disease-modifying agent for late-stage transthyretin amyloidosis}, journal = {Scientific Reports}, volume = {6}, year = {2016}, note = {Cited By :10Export Date: 19 March 2018}, month = {2016}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84969921377\&doi=10.1038\%2fsrep26623\&partnerID=40\&md5=6dba1ba0bad80de99de6426044ae291c}, author = {Ferreira, N. and Gon{\c c}alves, N.P. and Saraiva, M.J. and Almeida, M.R.} } @article {6627, title = {Efficiency of silencing RNA for removal of transthyretin V30M in a TTR leptomeningeal animal model}, journal = {Amyloid}, volume = {23}, year = {2016}, note = {Export Date: 19 March 2018}, month = {2016}, pages = {249 - 253}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84997124349\&doi=10.1080\%2f13506129.2016.1256282\&partnerID=40\&md5=7df3b3801dd8932604a8fb247164b88f}, author = {Gon{\c c}alves, P. and Martins, H. and Costelha, S. and Maia, L.F. and Saraiva, M.J.} } @article {6716, title = {Evidence for synergistic action of transthyretin and IGF-I over the IGF-I receptor}, journal = {Biochimica et Biophysica Acta - Molecular Basis of Disease}, volume = {1862}, year = {2016}, note = {Cited By :1Export Date: 19 March 2018}, month = {2016}, pages = {797 - 804}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84958526939\&doi=10.1016\%2fj.bbadis.2016.01.008\&partnerID=40\&md5=3df5d80ce654ff4b62c7eed851281863}, author = {Vieira, M. and Leal, S.S. and Gomes, C.M. and Saraiva, M.J.} } @article {6664, title = {Gd-nanoparticles functionalization with specific peptides for {\ss}-amyloid plaques targeting}, journal = {Journal of Nanobiotechnology}, volume = {14}, year = {2016}, note = {Cited By :5Export Date: 19 March 2018}, month = {2016}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84979272576\&doi=10.1186\%2fs12951-016-0212-y\&partnerID=40\&md5=6209a3372944548f54c22dfb5abcec38}, author = {Plissonneau, M. and Pansieri, J. and Heinrich-Balard, L. and Morfin, J.-F. and Stransky-Heilkron, N. and Rivory, P. and Mowat, P. and Dumoulin, M. and Cohen, R. and All{\'e}mann and T{\'o}th and Saraiva, M.J. and Louis, C. and Tillement, O. and Forge, V. and Lux, F. and Marquette, C.} } @article {6784, title = {Impairment of autophagy by TTR V30M aggregates: In vivo reversal by TUDCA and curcumin}, journal = {Clinical Science}, volume = {130}, year = {2016}, note = {Cited By :4Export Date: 19 March 2018}, month = {2016}, pages = {1665 - 1675}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85014362637\&doi=10.1042\%2fCS20160075\&partnerID=40\&md5=305826da43fc67637fa64b8557d52df2}, author = {Teixeira, C.A. and Almeida, M.D.R. and Saraiva, M.J.} } @article {6778, title = {A novel bis-furan scaffold for transthyretin stabilization and amyloid inhibition}, journal = {European Journal of Medicinal Chemistry}, volume = {121}, year = {2016}, note = {Cited By :1Export Date: 19 March 2018}, month = {2016}, pages = {823 - 840}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84961839171\&doi=10.1016\%2fj.ejmech.2016.02.074\&partnerID=40\&md5=0f10f2da86425912e522ce94860d41a3}, author = {Sim{\~o}es, C.J.V. and Almeida, Z.L. and Costa, D. and Jesus, C.S.H. and Cardoso, A.L. and Almeida, M.R. and Saraiva, M.J. and Pinho e Melo, T.M.V.D. and Brito, R.M.M.} } @article {6674, title = {Overexpression of Protocadherin-10 in Transthyretin-Related Familial Amyloidotic Polyneuropathy}, journal = {American Journal of Pathology}, volume = {186}, year = {2016}, note = {Cited By :3Export Date: 19 March 2018}, month = {2016}, pages = {1913 - 1924}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84997207695\&doi=10.1016\%2fj.ajpath.2016.02.020\&partnerID=40\&md5=97a50338db1d0b22348de0cb62438d42}, author = {Gon{\c c}alves, N.P. and Martins, D. and Saraiva, M.J.} } @article {6715, title = {Preclinical evaluation of RNAi as a treatment for transthyretin-mediated amyloidosis}, journal = {Amyloid}, volume = {23}, year = {2016}, note = {Cited By :21Export Date: 19 March 2018}, month = {2016}, pages = {109 - 118}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84962124696\&doi=10.3109\%2f13506129.2016.1160882\&partnerID=40\&md5=1d93178940883bb9f370cad870844c7f}, author = {Butler, J.S. and Chan, A. and Costelha, S. and Fishman, S. and Willoughby, J.L.S. and Borland, T.D. and Milstein, S. and Foster, D.J. and Gon{\c c}alves, P. and Chen, Q. and Qin, J. and Bettencourt, B.R. and Sah, D.W. and Alvarez, R. and Rajeev, K.G. and Manoharan, M. and Fitzgerald, K. and Meyers, R.E. and Nochur, S.V. and Saraiva, M.J. and Zimmermann, T.S.} } @article {6606, title = {Tissue remodeling after interference RNA mediated knockdown of transthyretin in a familial amyloidotic polyneuropathy mouse model}, journal = {Neurobiology of Aging}, volume = {47}, year = {2016}, note = {Cited By :2Export Date: 19 March 2018}, month = {2016}, pages = {91 - 101}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84983775600\&doi=10.1016\%2fj.neurobiolaging.2016.07.020\&partnerID=40\&md5=337cf6f5cf1e218eb03882752a85af98}, author = {Gon{\c c}alves, N.P. and Gon{\c c}alves, P. and Magalhaes, J. and Ventosa, M. and Coelho, A.V. and Saraiva, M.J.} } @article {6748, title = {Transthyretin participates in beta-amyloid transport from the brain to the liver- involvement of the low-density lipoprotein receptor-related protein 1?}, journal = {Scientific Reports}, volume = {6}, year = {2016}, note = {Cited By :6Export Date: 19 March 2018}, month = {2016}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84957818760\&doi=10.1038\%2fsrep20164\&partnerID=40\&md5=e1accbb7f4fb11c91f9e69d98092533f}, author = {Alemi, M. and Gaiteiro, C. and Ribeiro, C.A. and Santos, L.M. and Gomes, J.R. and Oliveira, S.M. and Couraud, P.-O. and Weksler, B. and Romero, I. and Saraiva, M.J. and Cardoso, I.} } @article {6609, title = {Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemia}, journal = {Cell Death and Differentiation}, volume = {23}, year = {2016}, note = {Cited By :9Export Date: 19 March 2018}, month = {2016}, pages = {1749 - 1764}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84982105742\&doi=10.1038\%2fcdd.2016.64\&partnerID=40\&md5=a23e97a5e41a8f9206f5040924716170}, author = {Gomes, J.R. and Nogueira, R.S. and Vieira, M. and Santos, S.D. and Ferraz-Nogueira, J.P. and Relvas, J.B. and Saraiva, M.J.} } @article {5459, title = {Polymer-doxycycline conjugates as fibril disrupters: An approach towards the treatment of a rare amyloidotic disease}, journal = {Journal of Controlled Release}, volume = {198}, year = {2015}, note = {Export Date: 12 January 2016}, month = {2015}, pages = {80 - 90}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84917690965\&partnerID=40\&md5=7ebabff2949d8d53f0872031375cc88e}, author = {Conejos-S{\'a}nchez, I. and Cardoso, I. and Oteo-Vives, M. and Romero-Sanz, E. and Paul, A. and Sauri, A.R. and Morcillo, M.A. and Saraiva, M.J. and Vicent, M.J.} } @article {5520, title = {Protective role of anakinra against transthyretin-mediated axonal loss and cell death in a mouse model of familial amyloidotic polyneuropathy}, journal = {Journal of Neuropathology and Experimental Neurology}, volume = {74}, year = {2015}, note = {Export Date: 12 January 2016}, month = {2015}, pages = {203 - 217}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84923701097\&partnerID=40\&md5=74ea39bf45cc4d7c36e971620cf78f60}, author = {Gon{\c c}alves, N. 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I. and Daphnis, E.} } @article {4764, title = {Presence of N-glycosylated transthyretin in plasma of V30M carriers in familial amyloidotic polyneuropathy: An escape from ERAD}, journal = {Journal of Cellular and Molecular Medicine}, volume = {17}, year = {2013}, note = {Cited By (since 1996):2Export Date: 8 April 2014Source: Scopus}, month = {2013}, pages = {429 - 435}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84875784710\&partnerID=40\&md5=06dd8c1d35d4b3d94e773a4b8e7b73da}, author = {Teixeira, A.C. and Saraiva, M.J.} } @article {4717, title = {Transthyretin regulates hippocampal 14-3-3ζ protein levels}, journal = {FEBS Letters}, volume = {587}, year = {2013}, note = {Cited By (since 1996):1Export Date: 8 April 2014Source: Scopus}, month = {2013}, pages = {1482 - 1488}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84877742326\&partnerID=40\&md5=89be84c52155c1d708a7c1e38efe7a75}, author = {Vieira, M. and Saraiva, M.J.} } @article {2873, title = {Clearance of extracellular misfolded proteins in systemic amyloidosis: Experience with transthyretin}, journal = {FEBS Letters}, volume = {586}, year = {2012}, note = {Export Date: 18 March 2013Source: Scopus}, month = {2012///}, pages = {2891 - 2896}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84864931018\&partnerID=40\&md5=7e26ae250f6b885e94435e7a9b447aae}, author = {Almeida, M.R. and Saraiva, M.J.} } @article {2859, title = {Distinct Annular Oligomers Captured along the Assembly and Disassembly Pathways of Transthyretin Amyloid Protofibrils}, journal = {PLoS ONE}, volume = {7}, year = {2012}, note = {Export Date: 18 March 2013Source: ScopusArt. No.: e44992}, month = {2012///}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84866318129\&partnerID=40\&md5=87126afbfde459837bcd031cf40d5a5d}, author = {Pires, R.H. and Karsai, {\'A}. and Saraiva, M.J. and Damas, A.M. and Kellermayer, M.S.Z.} } @article {2919, title = {Doxycycline plus tauroursodeoxycholic acid for transthyretin amyloidosis: A phase II study}, journal = {Amyloid}, volume = {19}, year = {2012}, note = {Cited By (since 1996): 5Export Date: 18 March 2013Source: Scopus}, month = {2012///}, pages = {34 - 36}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84861423778\&partnerID=40\&md5=a37fc893196a50627b0e0c02f8808946}, author = {Obici, L. and Cortese, A. and Lozza, A. and Lucchetti, J. and Gobbi, M. and Palladini, G. and Perlini, S. and Saraiva, M.J. and Merlini, G.} } @article {3004, title = {Epigallocatechin-3-gallate as a potential therapeutic drug for TTR-related amyloidosis: "In vivo" evidence from FAP mice models}, journal = {PLoS ONE}, volume = {7}, year = {2012}, note = {Cited By (since 1996): 7Export Date: 18 March 2013Source: ScopusArt. No.: e29933}, month = {2012///}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84855650426\&partnerID=40\&md5=3a4219629a4b3d658732a82d3448a7e4}, author = {Ferreira, N. and Saraiva, M.J. and Almeida, M.R.} } @article {2928, title = {The heat shock response in FAP: The role of the extracellular chaperone clusterin}, journal = {Amyloid}, volume = {19}, year = {2012}, note = {Export Date: 18 March 2013Source: Scopus}, month = {2012///}, pages = {3 - 4}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84861451360\&partnerID=40\&md5=cd710861696847e22e80aa111adaec70}, author = {Magalh{\~a}es, J. and Saraiva, M.J.} } @article {2923, title = {Natural polyphenols as modulators of TTR amyloidogenesis: In vitro and in vivo evidences towards therapy}, journal = {Amyloid}, volume = {19}, year = {2012}, note = {Cited By (since 1996): 1Export Date: 18 March 2013Source: Scopus}, month = {2012///}, pages = {39 - 42}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84861433687\&partnerID=40\&md5=850a84457e12b3b1a1ebabc339a6f5c8}, author = {Ferreira, N. and Saraiva, M.J. and Almeida, M.R.} } @article {2879, title = {A novel nanoparticle delivery system for in vivo targeting of the sciatic nerve: Impact on regeneration}, journal = {Nanomedicine}, volume = {7}, year = {2012}, note = {Export Date: 18 March 2013Source: Scopus}, month = {2012///}, pages = {1167 - 1180}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84868111412\&partnerID=40\&md5=5db0c76b3a921ca70565c9f3f63cf004}, author = {Gon{\c c}alves, N. P. and Oliveira, H. and P{\^e}go, A.P. and Saraiva, M.J.} } @article {2857, title = {Stability of the Transthyretin Molecule as a Key Factor in the Interaction with A-Beta Peptide - Relevance in Alzheimer{\textquoteright}s Disease}, journal = {PLoS ONE}, volume = {7}, year = {2012}, note = {Export Date: 18 March 2013Source: ScopusArt. No.: e45368}, month = {2012///}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84866460552\&partnerID=40\&md5=a0dfc2da5c8192925b47d6c264949fff}, author = {Ribeiro, C.A. and Saraiva, M.J. and Cardoso, I.} } @article {2831, title = {Transthyretin decrease in plasma of MCI and AD patients: Investigation of mechanisms for disease modulation}, journal = {Current Alzheimer Research}, volume = {9}, year = {2012}, note = {Export Date: 18 March 2013Source: Scopus}, month = {2012///}, pages = {881 - 889}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84867714724\&partnerID=40\&md5=3b8da808aabf04d44b80fdeced72c93b}, author = {Ribeiro, C.A. and Santana, I. and Oliveira, C. and Baldeiras, I. and Moreira, J. and Saraiva, M.J. and Cardoso, I.} } @article {2948, title = {Transthyretin deposition in familial amyloidotic polyneuropathy}, journal = {Current Medicinal Chemistry}, volume = {19}, year = {2012}, note = {Cited By (since 1996): 2Export Date: 18 March 2013Source: Scopus}, month = {2012///}, pages = {2304 - 2311}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84860663436\&partnerID=40\&md5=962004f2e8e201193cd9a0e0f5657bee}, author = {Saraiva, M.J. and Magalhaes, J. and Ferreira, N. and Almeida, M.R.} } @article {2949, title = {Transthyretin is a metallopeptidase with an inducible active site}, journal = {Biochemical Journal}, volume = {443}, year = {2012}, note = {Cited By (since 1996): 1Export Date: 18 March 2013Source: Scopus}, month = {2012///}, pages = {769 - 778}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84860178075\&partnerID=40\&md5=a10f2d32c644636fc246d7f79a171d2c}, author = {Liz, M.A. and Leite, S. C. and Juliano, L. and Saraiva, M.J. and Damas, A.M. and Bur, D. and Sousa, M.M.} } @article {3021, title = {Clusterin overexpression and its possible protective role in transthyretin deposition in familial amyloidotic polyneuropathy}, journal = {Journal of Neuropathology and Experimental Neurology}, volume = {70}, year = {2011}, note = {Cited By (since 1996): 3Export Date: 18 March 2013Source: Scopus}, month = {2011///}, pages = {1097 - 1106}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-81855199979\&partnerID=40\&md5=d083876d17665957abe15c74b03ee754}, author = {Magalh{\~a}es, J. and Saraiva, M.J.} } @article {3031, title = {Gender-dependent transthyretin modulation of brain amyloid-β Levels: Evidence from a mouse model of alzheimer{\textquoteright}s disease}, journal = {Journal of Alzheimer{\textquoteright}s Disease}, volume = {27}, year = {2011}, note = {Cited By (since 1996): 4Export Date: 18 March 2013Source: Scopus}, month = {2011///}, pages = {429 - 439}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-81855226408\&partnerID=40\&md5=366b9b479b431768dd24a7c10f0cccd5}, author = {Oliveira, S.M. and Ribeiro, C.A. and Cardoso, I. and Saraiva, M.J.} } @article {3149, title = {Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, volume = {108}, year = {2011}, note = {Cited By (since 1996): 8Export Date: 18 March 2013Source: Scopus}, month = {2011///}, pages = {5584 - 5589}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-79954990699\&partnerID=40\&md5=0a45c032e50290ca13d37fae9cbb2d1d}, author = {Noborna, F. and O{\textquoteright}Callaghan, P. and Hermansson, E. and Zhang, X. and Ancsin, J.B. and Damas, A.M. and Dacklin, I. and Presto, J. and Johansson, J. and Saraiva, M.J. and Lundgren, E. and Kisilevsky, R. and Westermark, P. and Li, J.-P.} } @article {3090, title = {Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation}, journal = {FEBS Letters}, volume = {585}, year = {2011}, note = {Cited By (since 1996): 17Export Date: 18 March 2013Source: Scopus}, month = {2011///}, pages = {2424 - 2430}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-79960910835\&partnerID=40\&md5=280da17ba91b02d23308cfcba9f21a31}, author = {Ferreira, N. and Saraiva, M.J. and Almeida, M.R.} } @article {3106, title = {Progesterone enhances transthyretin expression in the rat choroid plexus in vitro and in vivo via progesterone receptor}, journal = {Journal of Molecular Neuroscience}, volume = {44}, year = {2011}, note = {Cited By (since 1996): 3Export Date: 18 March 2013Source: Scopus}, month = {2011///}, pages = {152 - 158}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-80054082420\&partnerID=40\&md5=500e49fa5b69ae4c0cc22cd99f4c297e}, author = {Quintela, T. and Gon{\c c}alves, I. and Martinho, A. and Alves, C.H. and Saraiva, M.J. and Rocha, P. and Santos, C.R.A.} } @article {3051, title = {Solution structure of the soluble receptor for advanced glycation end products (sRAGE)}, journal = {Journal of Biological Chemistry}, volume = {286}, year = {2011}, note = {Cited By (since 1996): 3Export Date: 18 March 2013Source: Scopus}, month = {2011///}, pages = {37525 - 37534}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-80054814015\&partnerID=40\&md5=1e182fd947c34ba004f9841b73e692af}, author = {S{\'a}rk{\'a}ny, Z. and Ikonen, T.P. and Ferreira-Da-Silva, F. and Saraiva, M.J. and Svergun, D. and Damas, A.M.} } @article {3029, title = {Structural insights into a zinc-dependent pathway leading to Leu55Pro transthyretin amyloid fibrils}, journal = {Acta Crystallographica Section D: Biological Crystallography}, volume = {67}, year = {2011}, note = {Export Date: 18 March 2013Source: Scopus}, month = {2011///}, pages = {1035 - 1044}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-82455198838\&partnerID=40\&md5=0645f8740abbb950ca2171a6957fe25e}, author = {Castro-Rodrigues, A.F. and Gales, L. and Saraiva, M.J. and Damas, A.M.} } @article {3142, title = {Structure and assembly-disassembly properties of wild-type transthyretin amyloid protofibrils observed with atomic force microscopy}, journal = {Journal of Molecular Recognition}, volume = {24}, year = {2011}, note = {Cited By (since 1996): 5Export Date: 18 March 2013Source: Scopus}, month = {2011///}, pages = {467 - 476}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-79955124353\&partnerID=40\&md5=bc22f8a916d50ac2488a0a032fe1cf64}, author = {Pires, R.H. and Saraiva, M.J. and Damas, A.M. and Kellermayer, M.S.Z.} } @article {3162, title = {Successful heart and liver transplantation in a swiss patient with glu89lys transthyretin amyloidosis}, journal = {Transplantation}, volume = {91}, year = {2011}, note = {Export Date: 18 March 2013Source: Scopus}, month = {2011///}, pages = {e40 - e42}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-79952756738\&partnerID=40\&md5=cf899d4a6598ef5855d04b0c41a055a7}, author = {Niederhauser, J. and Lobrinus, J.A. and Ochsner, F. and Wider, C. and Fellmann, F. and Yerly, P. and Antonino, A.T. and Saraiva, M.J. and Moradpour, D. and Kuntzer, T.} } @article {3208, title = {Carvedilol treatment reduces transthyretin deposition in a familial amyloidotic polyneuropathy mouse model}, journal = {Pharmacological Research}, volume = {62}, year = {2010}, note = {Cited By (since 1996): 9Export Date: 18 March 2013Source: Scopus}, month = {2010///}, pages = {514 - 522}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-78049528674\&partnerID=40\&md5=842d6354261e0cf274c27f82c3a42eee}, author = {Macedo, B. and Magalh{\~a}es, J. and Batista, A.R. and Saraiva, M.J.} } @article {3256, title = {Controlling amyloid-β peptide(1-42) oligomerization and toxicity by fluorinated nanoparticles}, journal = {ChemBioChem}, volume = {11}, year = {2010}, note = {Cited By (since 1996): 7Export Date: 18 March 2013Source: Scopus}, month = {2010///}, pages = {1905 - 1913}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-77956253706\&partnerID=40\&md5=b542967bdceac2f960a6b916416c05d9}, author = {Saraiva, A.M. and Cardoso, I. and Pereira, M.C. and Coelho, M.A.N. and Saraiva, M.J. and M{\"o}hwald, H. and Brezesinski, G.} } @article {3211, title = {CSF transthyretin neuroprotection in a mouse model of brain ischemia}, journal = {Journal of Neurochemistry}, volume = {115}, year = {2010}, note = {Cited By (since 1996): 4Export Date: 18 March 2013Source: Scopus}, month = {2010///}, pages = {1434 - 1444}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-78650023374\&partnerID=40\&md5=e1f5719cb08d1a742e0859f007cfe6ac}, author = {Santos, S.D. and Lambertsen, K.L. and Clausen, B.H. and Akinc, A. and Alvarez, R. and Finsen, B. and Saraiva, M.J.} } @article {3363, title = {The heat shock response modulates transthyretin deposition in the peripheral and autonomic nervous systems}, journal = {Neurobiology of Aging}, volume = {31}, year = {2010}, note = {Cited By (since 1996): 14Export Date: 18 March 2013Source: Scopus}, month = {2010///}, pages = {280 - 289}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-71349088766\&partnerID=40\&md5=9cbceeed9e022c7ba7525c4ff755669b}, author = {Santos, S.D. and Fernandes, R. and Saraiva, M.J.} } @article {3269, title = {Human metallothioneins 2 and 3 differentially affect amyloid-beta binding by transthyretin}, journal = {FEBS Journal}, volume = {277}, year = {2010}, note = {Cited By (since 1996): 10Export Date: 18 March 2013Source: Scopus}, month = {2010///}, pages = {3427 - 3436}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-77955239777\&partnerID=40\&md5=8e3d909df1ca346d05af4045651d0b7d}, author = {Martinho, A. and Gon{\c c}alves, I. and Cardoso, I. and Almeida, M.R. and Quintela, T. and Saraiva, M.J. and Santos, C.R.A.} } @article {3254, title = {Randomization of Amyloid-β-Peptide(1-42) Conformation by Sulfonated and Sulfated Nanoparticles Reduces Aggregation and Cytotoxicity}, journal = {Macromolecular Bioscience}, volume = {10}, year = {2010}, note = {Cited By (since 1996): 8Export Date: 18 March 2013Source: Scopus}, month = {2010///}, pages = {1152 - 1163}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-78349265390\&partnerID=40\&md5=6e14b6224f7f2107acc29f0558258880}, author = {Saraiva, A.M. and Cardoso, I. and Saraiva, M.J. and Tauer, K. and Pereira, M.C. and Coelho, M.A.N. and M{\"o}hwald, H. and Brezesinski, G.} } @article {3274, title = {Synergy of combined Doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: Studies in FAP mouse models}, journal = {Journal of Translational Medicine}, volume = {8}, year = {2010}, note = {Cited By (since 1996): 23Export Date: 18 March 2013Source: ScopusArt. No.: 74}, month = {2010///}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-77954988796\&partnerID=40\&md5=4e545612ae485e8573fbd602222b48be}, author = {Cardoso, I. and Martins, D. and Ribeiro, T. and Merlini, G. and Saraiva, M.J.} } @article {3207, title = {αB-crystallin (HspB5) in familial amyloidotic polyneuropathy}, journal = {International Journal of Experimental Pathology}, volume = {91}, year = {2010}, note = {Cited By (since 1996): 6Export Date: 18 March 2013Source: Scopus}, month = {2010///}, pages = {515 - 521}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-78649515958\&partnerID=40\&md5=9d02f976955cf2ad57c4022e2d194f8a}, author = {Magalh{\~a}es, J. and Santos, S.D. and Saraiva, M.J.} } @article {3479, title = {17β-estradiol induces transthyretin expression in murine choroid plexus via an oestrogen receptor dependent pathway}, journal = {Cellular and Molecular Neurobiology}, volume = {29}, year = {2009}, note = {Cited By (since 1996): 12Export Date: 18 March 2013Source: Scopus}, month = {2009///}, pages = {475 - 483}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-67449156413\&partnerID=40\&md5=ab9fe51959e0d1e566f3cc7d5a7fb7af}, author = {Quintela, T. and Gon{\c c}alves, I. and Baltazar, G. and Alves, C.H. and Saraiva, M.J. and Santos, C.R.A.} } @article {3402, title = {Binding of epigallocatechin-3-gallate to transthyretin modulates its amyloidogenicity}, journal = {FEBS Letters}, volume = {583}, year = {2009}, note = {Cited By (since 1996): 20Export Date: 18 March 2013Source: Scopus}, month = {2009///}, pages = {3569 - 3576}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-71749085436\&partnerID=40\&md5=811ef79e7b3739a73a8a833f12c37ec5}, author = {Ferreira, N. and Cardoso, I. and Domingues, M.R. and Vitorino, R. and Bastos, M. and Bai, G. and Saraiva, M.J. and Almeida, M.R.} } @article {3522, title = {Design and biological activity of β-sheet breaker peptide conjugates}, journal = {Biochemical and Biophysical Research Communications}, volume = {380}, year = {2009}, note = {Cited By (since 1996): 13Export Date: 18 March 2013Source: Scopus}, month = {2009///}, pages = {397 - 401}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-60349104142\&partnerID=40\&md5=85946aef98ca4dc7b0be673d7a86b8cd}, author = {Rocha, S. and Cardoso, I. and B{\"o}rner, H. and Pereira, M.C. and Saraiva, M.J. and Coelho, M.} } @article {3550, title = {Iodine atoms: A new molecular feature for the design of potent transthyretin fibrillogenesis inhibitors}, journal = {PLoS ONE}, volume = {4}, year = {2009}, note = {Cited By (since 1996): 3Export Date: 18 March 2013Source: ScopusArt. No.: e4124}, month = {2009///}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-76549107471\&partnerID=40\&md5=3c50b3f528228e1cdcbdf338d86ca8ca}, author = {Mairal, T. and Nieto, J. and Pinto, M. and Almeida, M.R. and Gales, L. and Ballesteros, A. and Barluenga, J. and P{\'e}rez, J.J. and V{\'a}zquez, J.T. and Centeno, N.B. and Saraiva, M.J. and Damas, A.M. and Planas, A. and Arsequell, G. and Valencia, G.} } @article {3538, title = {Iodine atoms: a new molecular feature for the design of potent transthyretin fibrillogenesis inhibitors.}, journal = {PLoS ONE}, volume = {4}, year = {2009}, note = {Cited By (since 1996): 11Export Date: 18 March 2013Source: Scopus}, month = {2009///}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-59249100931\&partnerID=40\&md5=f198d6ea26cef74066becb41f537c7cd}, author = {Mairal, T. and Nieto, J. and Pinto, M. and Almeida, M.R. and Gales, L. and Ballesteros, A. and Barluenga, J. and P{\'e}rez, J.J. and V{\'a}zquez, J.T. and Centeno, N.B. and Saraiva, M.J. and Damas, A.M. and Planas, A. and Arsequell, G. and Valencia, G.} } @article {3446, title = {Isatin derivatives, a novel class of transthyretin fibrillogenesis inhibitors}, journal = {Bioorganic and Medicinal Chemistry Letters}, volume = {19}, year = {2009}, note = {Cited By (since 1996): 10Export Date: 18 March 2013Source: Scopus}, month = {2009///}, pages = {5270 - 5273}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-68549085257\&partnerID=40\&md5=b4cf7ffd46ddb61e0d802b209c39334d}, author = {Gonz{\'a}lez, A. and Quirante, J. and Nieto, J. and Almeida, M.R. and Saraiva, M.J. and Planas, A. and Arsequell, G. and Valencia, G.} } @article {3520, title = {Transthyretin internalization by sensory neurons is megalin mediated and necessary for its neuritogenic activity}, journal = {Journal of Neuroscience}, volume = {29}, year = {2009}, note = {Cited By (since 1996): 16Export Date: 18 March 2013Source: Scopus}, month = {2009///}, pages = {3220 - 3232}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-63849199799\&partnerID=40\&md5=83963e483535453d953104df3c18aa7f}, author = {Fleming, C.E. and Mar, F.M. and Franquinho, F. and Saraiva, M.J. and Sousa, M.M.} } @article {3622, title = {5α-dihydrotestosterone up-regulates transthyretin levels in mice and rat choroid plexus via an androgen receptor independent pathway}, journal = {Brain Research}, volume = {1229}, year = {2008}, note = {Cited By (since 1996): 9Export Date: 18 March 2013Source: Scopus}, month = {2008///}, pages = {18 - 26}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-49849091809\&partnerID=40\&md5=5ef9298fe6436cc5656fc496a2e39043}, author = {Quintela, T. and Alves, C.H. and Gon{\c c}alves, I. and Baltazar, G. and Saraiva, M.J. and Santos, C.R.A.} } @article {3697, title = {Activation of the heat shock response in familial amyloidotic polyneuropathy}, journal = {Journal of Neuropathology and Experimental Neurology}, volume = {67}, year = {2008}, note = {Cited By (since 1996): 8Export Date: 18 March 2013Source: Scopus}, month = {2008///}, pages = {449 - 455}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-43249124993\&partnerID=40\&md5=6b03a31f0fda714bddf1e2f71eac4878}, author = {Santos, S.D. and Magalh{\~a}es, J. and Saraiva, M.J.} } @article {3645, title = {Amyloidogenic properties of transthyretin-like protein (TLP) from Escherichia coli}, journal = {FEBS Letters}, volume = {582}, year = {2008}, note = {Cited By (since 1996): 3Export Date: 18 March 2013Source: Scopus}, month = {2008///}, pages = {2893 - 2898}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-48749127539\&partnerID=40\&md5=226fe223f9cd17ff866d8d30fde172aa}, author = {Santos, S.D. and Costa, R. and Teixeira, P.F. and Gottesman, M. and Cardoso, I. and Saraiva, M.J.} } @article {3627, title = {Anti-apoptotic treatment reduces transthyretin deposition in a transgenic mouse model of Familial Amyloidotic Polyneuropathy}, journal = {Biochimica et Biophysica Acta - Molecular Basis of Disease}, volume = {1782}, year = {2008}, note = {Cited By (since 1996): 15Export Date: 18 March 2013Source: Scopus}, month = {2008///}, pages = {517 - 522}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-49349097870\&partnerID=40\&md5=0504bdb8449a5ce447da5feb06674ee6}, author = {Macedo, B. and Batista, A.R. and Ferreira, N. and Almeida, M.R. and Saraiva, M.J.} } @article {3630, title = {Extracellular matrix markers for disease progression and follow-up of therapies in familial amyloid polyneuropathy V30M TTR-related}, journal = {Disease Markers}, volume = {25}, year = {2008}, note = {Cited By (since 1996): 5Export Date: 18 March 2013Source: Scopus}, month = {2008///}, pages = {37 - 47}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-50249169221\&partnerID=40\&md5=81e51d4cb7675f693c1aa8a82ba14b67}, author = {Cardoso, I. and Brito, M. and Saraiva, M.J.} } @article {3734, title = {Iodination of salicylic acid improves its binding to transthyretin}, journal = {Biochimica et Biophysica Acta - Proteins and Proteomics}, volume = {1784}, year = {2008}, note = {Cited By (since 1996): 6Export Date: 18 March 2013Source: Scopus}, month = {2008///}, pages = {512 - 517}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-43049162388\&partnerID=40\&md5=ef1bf96239ccea9c357c15a1c430e7d9}, author = {Gales, L. and Almeida, M.R. and Arsequell, G. and Valencia, G. and Saraiva, M.J. and Damas, A.M.} } @article {3728, title = {Transthyretin binding to A-Beta peptide - Impact on A-Beta fibrillogenesis and toxicity}, journal = {FEBS Letters}, volume = {582}, year = {2008}, note = {Cited By (since 1996): 35Export Date: 18 March 2013Source: Scopus}, month = {2008///}, pages = {936 - 942}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-40149086952\&partnerID=40\&md5=b0d6992afb840ae8f064de549718a3a7}, author = {Costa, R. and Gon{\c c}alves, A. and Saraiva, M.J. and Cardoso, I.} } @article {3581, title = {Transthyretin is not expressed by dorsal root ganglia cells}, journal = {Experimental Neurology}, volume = {214}, year = {2008}, note = {Cited By (since 1996): 6Export Date: 18 March 2013Source: Scopus}, month = {2008///}, pages = {362 - 365}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-56349106019\&partnerID=40\&md5=85691d0172fa5dd81d01158a2968961c}, author = {Sousa, M.M. and Saraiva, M.J.} } @article {3649, title = {Transthyretin protects against A-beta peptide toxicity by proteolytic cleavage of the peptide: A mechanism sensitive to the kunitz protease inhibitor}, journal = {PLoS ONE}, volume = {3}, year = {2008}, note = {Cited By (since 1996): 28Export Date: 18 March 2013Source: ScopusArt. No.: e2899}, month = {2008///}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-51449096179\&partnerID=40\&md5=3e177d160640c25dd736e373e8674d7b}, author = {Costa, R. and Ferreira-Da-Silva, F. and Saraiva, M.J. and Cardoso, I.} } @article {3862, title = {Accelerated Aβ deposition in APPswe/PS1ΔE9 mice with hemizygous deletions of TTR (transthyretin)}, journal = {Journal of Neuroscience}, volume = {27}, year = {2007}, note = {Cited By (since 1996): 51Export Date: 18 March 2013Source: Scopus}, month = {2007///}, pages = {7006 - 7010}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-34347364708\&partnerID=40\&md5=fe6c961bd198393502e3effe5fbcedff}, author = {Se, H.C. and Leight, S.N. and Lee, V.M.-Y. and Li, T. and Wong, P.C. and Johnson, J.A. and Saraiva, M.J. and Sisodia, S.S.} } @article {3788, title = {ApoA-I cleaved by transthyretin has reduced ability to promote cholesterol efflux and increased amyloidogenicity}, journal = {Journal of Lipid Research}, volume = {48}, year = {2007}, note = {Cited By (since 1996): 31Export Date: 18 March 2013Source: Scopus}, month = {2007///}, pages = {2385 - 2395}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-35848967214\&partnerID=40\&md5=1f602c3eef034920c7b5e648c0d9cb36}, author = {Liz, M.A. and Gomes, C.M. and Saraiva, M.J. and Sousa, M.M.} } @article {3789, title = {Biomarkers in the assessment of therapies for familial amyloidotic polyneuropathy}, journal = {Molecular Medicine}, volume = {13}, year = {2007}, note = {Cited By (since 1996): 13Export Date: 18 March 2013Source: Scopus}, month = {2007///}, pages = {584 - 591}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-36849096153\&partnerID=40\&md5=c97d9b2e7a6637ff3cf8e866249b362a}, author = {Macedo, B. and Batista, A.R. and Do Amaral, J.B. and Saraiva, M.J.} } @article {3785, title = {Comparative in vitro and ex vivo activities of selected inhibitors of transthyretin aggregation: Relevance in drug design}, journal = {Biochemical Journal}, volume = {408}, year = {2007}, note = {Cited By (since 1996): 13Export Date: 18 March 2013Source: Scopus}, month = {2007///}, pages = {131 - 138}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-36348960658\&partnerID=40\&md5=a11be6d9183785b213d1ee7ad796276b}, author = {Cardoso, I. and Almeida, M.R. and Ferreira, N. and Arsequell, G. and Valencia, G. and Saraiva, M.J.} } @article {3877, title = {Genetic microheterogeneity of human transthyretin detected by IEF}, journal = {Electrophoresis}, volume = {28}, year = {2007}, note = {Cited By (since 1996): 15Export Date: 18 March 2013Source: Scopus}, month = {2007///}, pages = {2053 - 2064}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-34447271771\&partnerID=40\&md5=3783cb1408f7c43a1a52d1b746ae3392}, author = {Altland, K. and Benson, M.D. and Costello, C.E. and Ferlini, A. and Hazenberg, B.P.C. and Hund, E. and Kristen, A.V. and Linke, R.P. and Merlini, G. and Salvi, F. and Saraiva, M.J. and Singer, R. and Skinner, M. and Winter, P.} } @article {3808, title = {Impairment of the ubiquitin-proteasome system associated with extracellular transthyretin aggregates in familial amyloidotic polyneuropathy}, journal = {Journal of Pathology}, volume = {213}, year = {2007}, note = {Cited By (since 1996): 7Export Date: 18 March 2013Source: Scopus}, month = {2007///}, pages = {200 - 209}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-35348937731\&partnerID=40\&md5=482f98b830ce45b3f8b85a4e22658985}, author = {Santos, S.D. and Cardoso, I. and Magalh{\~a}es, J. and Saraiva, M.J.} } @article {3831, title = {A primer of amyloid nomenclature}, journal = {Amyloid}, volume = {14}, year = {2007}, note = {Cited By (since 1996): 137Export Date: 18 March 2013Source: Scopus}, month = {2007///}, pages = {179 - 183}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-34547913439\&partnerID=40\&md5=8c948b61d2a53517054e2a820457338e}, author = {Westermark, P. and Benson, M.D. and Buxbaum, J.N. and Cohen, A.S. and Frangione, B. and Ikeda, S.-I. and Masters, C.L. and Merlini, G. and Saraiva, M.J. and Sipe, J.D.} } @article {3956, title = {Structural basis for the protective role of sulfite against transthyretin amyloid formation}, journal = {Biochimica et Biophysica Acta - Proteins and Proteomics}, volume = {1774}, year = {2007}, note = {Cited By (since 1996): 6Export Date: 18 March 2013Source: Scopus}, month = {2007///}, pages = {59 - 64}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-33846117955\&partnerID=40\&md5=17fca5b67bb79c6b143645e3a7a127db}, author = {Gales, L. and Saraiva, M.J. and Damas, A.M.} } @article {3894, title = {Transthyretin and Alzheimer{\textquoteright}s disease: Where in the brain?}, journal = {Neurobiology of Aging}, volume = {28}, year = {2007}, note = {Cited By (since 1996): 44Export Date: 18 March 2013Source: Scopus}, month = {2007///}, pages = {713 - 718}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-33847345982\&partnerID=40\&md5=25b127ef65fc87b0b083cafb1e7abf78}, author = {Sousa, J.C. and Cardoso, I. and Marques, F. and Saraiva, M.J. and Palha, J.A.} } @article {3811, title = {Transthyretin enhances nerve regeneration}, journal = {Journal of Neurochemistry}, volume = {103}, year = {2007}, note = {Cited By (since 1996): 32Export Date: 18 March 2013Source: Scopus}, month = {2007///}, pages = {831 - 839}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-34848818080\&partnerID=40\&md5=35aebeab8665985741e3fa5c178045b4}, author = {Fleming, C.E. and Saraiva, M.J. and Sousa, M.M.} } @article {3812, title = {Transthyretin: No association between serum levels or gene variants and schizophrenia}, journal = {Journal of Psychiatric Research}, volume = {41}, year = {2007}, note = {Cited By (since 1996): 5Export Date: 18 March 2013Source: Scopus}, month = {2007///}, pages = {667 - 672}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-33947663895\&partnerID=40\&md5=9856da904a660f965a6e0bbb048a6d74}, author = {Ruano, D. and Macedo, A. and Soares, M.J. and Valente, J. and Azevedo, M.H. and Hutz, M.H. and Gama, C.S. and Lobato, M.I. and Belmonte-de-Abreu, P. and Goodman, A.B. and Pato, C. and Saraiva, M.J. and Heutink, P. and Palha, J.A.} } @article {4066, title = {Activation of ERK1/2 MAP kinases in familial amyloidotic polyneuropathy}, journal = {Journal of Neurochemistry}, volume = {97}, year = {2006}, note = {Cited By (since 1996): 22Export Date: 18 March 2013Source: Scopus}, month = {2006///}, pages = {151 - 161}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-33644951055\&partnerID=40\&md5=a80dca988de81f6c4ce57f2b0b9cec7d}, author = {Monteiro, F.A. and Sousa, M.M. and Cardoso, I. and Do Amaral, J.B. and Guimar{\~a}es, A. and Saraiva, M.J.} } @article {4059, title = {The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin}, journal = {Acta Crystallographica Section D: Biological Crystallography}, volume = {62}, year = {2006}, note = {Cited By (since 1996): 7Export Date: 18 March 2013Source: Scopus}, month = {2006///}, pages = {512 - 519}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-33646538797\&partnerID=40\&md5=338596bd3e63c2c24bf943c16da8c833}, author = {Morais-De-S{\'a}, E. and Neto-Silva, R.M. and Pereira, P.J.B. and Saraiva, M.J. and Damas, A.M.} } @article {4087, title = {Doxycycline disrupts transthyretin amyloid: Evidence from studies in a FAP transgenic mice model}, journal = {FASEB Journal}, volume = {20}, year = {2006}, note = {Cited By (since 1996): 33Export Date: 18 March 2013Source: Scopus}, month = {2006///}, pages = {234 - 239}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-33644919388\&partnerID=40\&md5=95aeaf885f334f0968f8be8124190c1f}, author = {Cardoso, I. and Saraiva, M.J.} } @article {4009, title = {Endoplasmic reticulum stress associated with extracellular aggregates: Evidence from transthyretin deposition in familial amyloid polyneuropathy}, journal = {Journal of Biological Chemistry}, volume = {281}, year = {2006}, note = {Cited By (since 1996): 28Export Date: 18 March 2013Source: Scopus}, month = {2006///}, pages = {21998 - 22003}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-33746814859\&partnerID=40\&md5=1527690776df3238c8ef0c9af77029a3}, author = {Teixeira, P.F. and Cerca, F. and Santos, S.D. and Saraiva, M.J.} } @article {4095, title = {Immunization in familial amyloidotic polyneuropathy: Counteracting deposition by immunization with a Y78F TTR mutant}, journal = {Laboratory Investigation}, volume = {86}, year = {2006}, note = {Cited By (since 1996): 23Export Date: 18 March 2013Source: Scopus}, month = {2006///}, pages = {23 - 31}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-32844473029\&partnerID=40\&md5=59870e65ae8c707030fc2fabbbb1ad2a}, author = {Terazaki, H. and Ando, Y. and Fernandes, R. and Yamamura, K.-I. and Maeda, S. and Saraiva, M.J.} } @article {4036, title = {In vitro inhibition of transthyretin aggregate-induced cytotoxicity by full and peptide derived forms of the soluble receptor for advanced glycation end products (RAGE)}, journal = {FEBS Letters}, volume = {580}, year = {2006}, note = {Cited By (since 1996): 11Export Date: 18 March 2013Source: Scopus}, month = {2006///}, pages = {3451 - 3456}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-33646925693\&partnerID=40\&md5=2846be0696b1b600db21d05b697a5047}, author = {Monteiro, F.A. and Cardoso, I. and Sousa, M.M. and Saraiva, M.J.} } @article {4099, title = {Transthyretin knockouts are a new mouse model for increased neuropeptide Y}, journal = {FASEB Journal}, volume = {20}, year = {2006}, note = {Cited By (since 1996): 30Export Date: 18 March 2013Source: Scopus}, month = {2006///}, pages = {166 - 168}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-30744463914\&partnerID=40\&md5=e0c56af329be5a5556f91a1d4065f2a0}, author = {Nunes, A.F. and Saraiva, M.J. and Sousa, M.M.} } @article {4203, title = {Amyloid: Toward terminology clarification: Report from the Nomenclature Committee of the International Society Of Amyloidosis}, journal = {Amyloid}, volume = {12}, year = {2005}, note = {Cited By (since 1996): 162Export Date: 18 March 2013Source: Scopus}, month = {2005///}, pages = {1 - 4}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-21244471488\&partnerID=40\&md5=e85f0145e3c5c04c572c9472e754ef48}, author = {Westermark, P. and Benson, M.D. and Buxbaum, J.N. and Cohen, A.S. and Frangione, B. and Ikeda, S.-I. and Masters, C.L. and Merlini, G. and Saraiva, M.J. and Sipe, J.D.} } @article {4101, title = {The binding of xanthone derivatives to transthyretin}, journal = {Biochemical Pharmacology}, volume = {70}, year = {2005}, note = {Cited By (since 1996): 17Export Date: 18 March 2013Source: Scopus}, month = {2005///}, pages = {1861 - 1869}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-27744528447\&partnerID=40\&md5=7c93acb645a047686e7d0f1ce0f0b9d2}, author = {Maia, F. and Almeida, M.D.R. and Gales, L. and Kijjoa, A. and Pinto, M.M.M. and Saraiva, M.J. and Damas, A.M.} } @article {4178, title = {Human transthyretin in complex with iododiflunisal: Structural features associated with a potent amyloid inhibitor}, journal = {Biochemical Journal}, volume = {388}, year = {2005}, note = {Cited By (since 1996): 23Export Date: 18 March 2013Source: Scopus}, month = {2005///}, pages = {615 - 621}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-20544432502\&partnerID=40\&md5=fb1f280ed65d3acbafe190a6c6616e93}, author = {Gales, L. and Macedo-Ribeiro, S. and Arsequell, G. and Valencia, G. and Saraiva, M.J. and Damas, A.M.} } @article {4142, title = {Small transthyretin (TTR) ligands as possible therapeutic agents in TTR amyloidoses}, journal = {Current Drug Targets: CNS and Neurological Disorders}, volume = {4}, year = {2005}, note = {Cited By (since 1996): 22Export Date: 18 March 2013Source: Scopus}, month = {2005///}, pages = {587 - 596}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-26844484754\&partnerID=40\&md5=af4ca78d8342a69428684780d78b9e87}, author = {Almeida, M.R. and Gales, L. and Damas, A.M. and Cardoso, I. and Saraiva, M.J.} } @article {4214, title = {Susceptibility and modifier genes in Portuguese transthyretin V30M amyloid polyneuropathy: Complexity in a single-gene disease}, journal = {Human Molecular Genetics}, volume = {14}, year = {2005}, note = {Cited By (since 1996): 49Export Date: 18 March 2013Source: Scopus}, month = {2005///}, pages = {543 - 553}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-14044275133\&partnerID=40\&md5=5f500d0e193d96fb0a5345b92d71b2ba}, author = {Soares, M.L. and Coelho, T. and Sousa, A. and Batalov, S. and Concei{\c c}{\~a}o, I. and Sales-Lu{\'\i}s, M.L. and Ritchie, M.D. and Williams, S.M. and Nievergelt, C.M. and Schork, N.J. and Saraiva, M.J. and Buxbaum, J.N.} } @article {4127, title = {Transthyretin is not necessary for thyroid hormone metabolism in conditions of increased hormone demand}, journal = {Journal of Endocrinology}, volume = {187}, year = {2005}, note = {Cited By (since 1996): 6Export Date: 18 March 2013Source: Scopus}, month = {2005///}, pages = {257 - 266}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-28044432318\&partnerID=40\&md5=43094d768ab19396e88f3beb3fa4ac3e}, author = {Sousa, J.C. and Morreale de Escobar, G. and Oliveira, P. and Saraiva, M.J. and Palha, J.A.} } @article {4233, title = {Up-regulation of the extracellular matrix remodeling genes, biglycan, neutrophil gelatinase-associated lipocalin, and matrix metalloproteinase-9 in familial amyloid polyneuropathy}, journal = {FASEB Journal}, volume = {19}, year = {2005}, note = {Cited By (since 1996): 23Export Date: 18 March 2013Source: Scopus}, month = {2005///}, pages = {124 - 126}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-11244280869\&partnerID=40\&md5=c12a25ef29d75356ace32fde2a907338}, author = {Sousa, M.M. and Do Amaral, J.B. and Guimar{\~a}es, A. and Saraiva, M.J.} } @article {4211, title = {X-ray crystallographic studies of two transthyretin variants: Further insights into amyloidogenesis}, journal = {Acta Crystallographica Section D: Biological Crystallography}, volume = {61}, year = {2005}, note = {Cited By (since 1996): 9Export Date: 18 March 2013Source: Scopus}, month = {2005///}, pages = {333 - 339}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-24044453447\&partnerID=40\&md5=17b3c85c5e78599513794d167c43a49e}, author = {Neto-Silva, R.M. and Macedo-Ribeiro, S. and Pereira, P.J.B. and Coll, M. and Saraiva, M.J. and Damas, A.M.} } @article {4315, title = {Common origin of the Val30Met mutation responsible for the amyloidogenic transthyretin type of familial amyloidotic polyneuropathy.}, journal = {Journal of medical genetics}, volume = {41}, year = {2004}, note = {Cited By (since 1996): 16Export Date: 18 March 2013Source: Scopus}, month = {2004///}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-2342614233\&partnerID=40\&md5=fb2e8747448af9b1e28fcf2650bb3b32}, author = {Ohmori, H. and Ando, Y. and Makita, Y. and Onouchi, Y. and Nakajima, T. and Saraiva, M.J. and Terazaki, H. and Suhr, O. and Sobue, G. and Nakamura, M. and Yamaizumi, M. and Munar-Ques, M. and Inoue, I. and Uchino, M. and Hata, A.} } @article {4239, title = {The crystal structure of transthyretin in complex with diethylstilbestrol: A promising template for the design of amyloid inhibitors}, journal = {Journal of Biological Chemistry}, volume = {279}, year = {2004}, note = {Cited By (since 1996): 25Export Date: 18 March 2013Source: Scopus}, month = {2004///}, pages = {53483 - 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