TY - JOUR T1 - Cholesteryl hemiesters alter lysosome structure and function and induce proinflammatory cytokine production in macrophages JF - Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids Y1 - 2017 A1 - Domingues, N. A1 - Estronca, L.M.B.B. A1 - Silva, J. A1 - Encarnação, M.R. A1 - Mateus, R. A1 - Silva, D. A1 - Santarino, I.B. A1 - Saraiva, M. A1 - Soares, M.I.L. A1 - Pinho e Melo, T.M.V.D. A1 - Jacinto, A. A1 - Vaz, W.L.C. A1 - Vieira, O.V. VL - 1862 UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84999089924&doi=10.1016%2fj.bbalip.2016.10.009&partnerID=40&md5=d0ff554708121503d020d50261bd055d IS - 2 N1 - Cited By :1Export Date: 19 March 2018 ER - TY - JOUR T1 - Differential expression of Cathepsin E in transthyretin amyloidosis: From neuropathology to the immune system JF - Journal of Neuroinflammation Y1 - 2017 A1 - Gonçalves, N.P. A1 - Moreira, J. A1 - Martins, D. A1 - Vieira, P. A1 - Obici, L. A1 - Merlini, G. A1 - Saraiva, M. A1 - Saraiva, M.J. VL - 14 UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85020206626&doi=10.1186%2fs12974-017-0891-9&partnerID=40&md5=b9f1e2ecd68f694c037715a33142d46c IS - 1 N1 - Export Date: 19 March 2018 ER - TY - JOUR T1 - Experimental study of tuberculosis: From animal models to complex cell systems and organoids JF - PLoS Pathogens Y1 - 2017 A1 - Fonseca, K.L. A1 - Rodrigues, P.N.S. A1 - Olsson, I.A.S. A1 - Saraiva, M. VL - 13 UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028681914&doi=10.1371%2fjournal.ppat.1006421&partnerID=40&md5=0071bb23a707c62f74890b89a81e2ef0 IS - 8 N1 - Cited By :1Export Date: 19 March 2018 ER - TY - JOUR T1 - IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity JF - Journal of Allergy and Clinical Immunology Y1 - 2017 A1 - Cunha, C. A1 - Gonçalves, S.M. A1 - Duarte-Oliveira, C. A1 - Leite, L. A1 - Lagrou, K. A1 - Marques, A. A1 - Lupiañez, C.B. A1 - Mesquita, I. A1 - Gaifem, J. A1 - Barbosa, A.M. A1 - Pinho Vaz, C. A1 - Branca, R. A1 - Campilho, F. A1 - Freitas, F. A1 - Ligeiro, D. A1 - Lass-Flörl, C. A1 - Löffler, J. A1 - Jurado, M. A1 - Saraiva, M. A1 - Kurzai, O. A1 - Rodrigues, F. A1 - Castro, A.G. A1 - Silvestre, R. A1 - Sainz, J. A1 - Maertens, J.A. A1 - Torrado, E. A1 - Jacobsen, I.D. A1 - Lacerda, J.F. A1 - Campos, Jr, A. A1 - Carvalho, A. VL - 140 UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019152778&doi=10.1016%2fj.jaci.2017.02.034&partnerID=40&md5=a854e39ec89e42f6bffed2d1e01cb966 IS - 3 N1 - Cited By :2Export Date: 19 March 2018 ER - TY - JOUR T1 - Interferon-β regulates the production of IL-10 by toll-like receptor-activated microglia JF - GLIA Y1 - 2017 A1 - Lobo-Silva, D. A1 - Carriche, G.M. A1 - Castro, A.G. A1 - Roque, S. A1 - Saraiva, M. VL - 65 UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021258982&doi=10.1002%2fglia.23172&partnerID=40&md5=7c712afbbfe1da8607e85b05fb3c71de IS - 9 N1 - Export Date: 19 March 2018 ER - TY - JOUR T1 - Balancing the immune response in the brain: IL-10 and its regulation JF - Journal of Neuroinflammation Y1 - 2016 A1 - Lobo-Silva, D. A1 - Carriche, G.M. A1 - Castro, A.G. A1 - Roque, S. A1 - Saraiva, M. VL - 13 UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84997106994&doi=10.1186%2fs12974-016-0763-8&partnerID=40&md5=1404ad30874932d8832e69dd63cd155c IS - 1 N1 - Cited By :18Export Date: 19 March 2018 ER - TY - JOUR T1 - Differential production of Type I IFN Determines the Reciprocal Levels of IL-10 and proinflammatory cytokines produced by C57BL/6 and BALB/c macrophages JF - Journal of Immunology Y1 - 2016 A1 - Howes, A. A1 - Taubert, C. A1 - Blankley, S. A1 - Spink, N. A1 - Wu, X. A1 - Graham, C.M. A1 - Zhao, J. A1 - Saraiva, M. A1 - Ricciardi-Castagnoli, P. A1 - Bancroft, G.J. A1 - O'Garra, A. VL - 197 UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84989939029&doi=10.4049%2fjimmunol.1501923&partnerID=40&md5=be062d803f4451e86effaa3931fce598 IS - 7 N1 - Cited By :9Export Date: 19 March 2018 ER - TY - JOUR T1 - A prediction rule to stratify mortality risk of patients with pulmonary tuberculosis JF - PLoS ONE Y1 - 2016 A1 - Bastos, H.N. A1 - Osório, N.S. A1 - Castro, A.G. A1 - Ramos, A. A1 - Carvalho, T. A1 - Meira, L. A1 - Araujo, D. A1 - Almeida, L. A1 - Boaventura, R. A1 - Fragata, P. A1 - Chaves, C. A1 - Costa, P. A1 - Portela, M. A1 - Ferreira, I. A1 - Magalhães, S.P. A1 - Rodrigues, F. A1 - Sarmento-Castro, R. A1 - Duarte, R. A1 - Guimarães, J.T. A1 - Saraiva, M. VL - 11 UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-84992386220&doi=10.1371%2fjournal.pone.0162797&partnerID=40&md5=189c5c76fc07b391d464bbc9f99f9c3a IS - 9 N1 - Cited By :2Export Date: 19 March 2018 ER - TY - JOUR T1 - Type i IFN inhibits alternative macrophage activation during mycobacterium tuberculosis infection and leads to enhanced protection in the absence of IFN-γ signaling JF - Journal of Immunology Y1 - 2016 A1 - Moreira-Teixeira, L. A1 - Sousa, J. A1 - McNab, F.W. A1 - Torrado, E. A1 - Cardoso, F. A1 - Machado, H. A1 - Castro, F. A1 - Cardoso, V. A1 - Gaifem, J. A1 - Wu, X. A1 - Appelberg, R. A1 - Castro, A.G. A1 - O'Garra, A. A1 - Saraiva, M. 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VL - 33 UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84919360521&partnerID=40&md5=7dc924fd77e380179495ca40f31bc4b7 IS - 1 N1 - Cited By :3Export Date: 12 January 2016 ER - TY - JOUR T1 - Corticosteroid-Induced Immunosuppression Ultimately Does Not Compromise the Efficacy of Antibiotherapy in Murine Mycobacterium ulcerans Infection JF - PLoS Neglected Tropical Diseases Y1 - 2012 A1 - Martins, T.G. A1 - Trigo, G. A1 - Fraga, A.G. A1 - Gama, J. B. A1 - Longatto-Filho, A. A1 - Saraiva, M. A1 - Silva, M.T. A1 - Castro, A.G. A1 - Pedrosa, J. VL - 6 UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84870754979&partnerID=40&md5=50acbdcfe603f787009744c75cb5e8f9 IS - 11 N1 - Export Date: 18 March 2013Source: ScopusArt. No.: e1925 ER - TY - JOUR T1 - Local and regional re-establishment of cellular immunity during curative antibiotherapy of murine mycobacterium ulcerans infection JF - PLoS ONE Y1 - 2012 A1 - Martins, T.G. A1 - Gama, J. B. A1 - Fraga, A.G. A1 - Saraiva, M. A1 - Silva, M.T. A1 - Castro, A.G. A1 - Pedrosa, J. VL - 7 UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84857676432&partnerID=40&md5=b71da77afac13b9a538a88d53f190592 IS - 2 N1 - Cited By (since 1996): 1Export Date: 18 March 2013Source: ScopusArt. No.: e32740 ER - TY - JOUR T1 - Mycobacterium ulcerans triggers T-cell immunity followed by local and regional but not systemic immunosuppression JF - Infection and Immunity Y1 - 2011 A1 - Fraga, A.G. A1 - Cruz, A. A1 - Martins, T.G. A1 - Torrado, E. A1 - Saraiva, M. A1 - Pereira, D.R. A1 - Meyers, W.M. A1 - Portaels, F. A1 - Silva, M.T. A1 - Castro, A.G. A1 - Pedrosal, J. VL - 79 UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-78650893587&partnerID=40&md5=8ee9a2efd46efaba0b7cb7f42d9b83df IS - 1 N1 - Cited By (since 1996): 6Export Date: 18 March 2013Source: Scopus ER -