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Pereira, C., Costa, V., Martins, L. M., & Saraiva, L. (2015). A yeast model of the Parkinson's disease-associated protein Parkin. Experimental Cell Research, 333(1), 73 - 79.

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Leino, H., Shunmugam, S., Isojärvi, J., Oliveira, P., et al. (2014). Characterization of ten H2 producing cyanobacteria isolated from the Baltic Sea and Finnish lakes. International Journal of Hydrogen Energy, 39(17), 8983 - 8991.

Ribeiro, P. O., Tomé, Â. R., Silva, H. B., Cunha, R. A., & Antunes, L. M. (2014). Clinically relevant concentrations of ketamine mainly affect long-term potentiation rather than basal excitatory synaptic transmission and do not change paired-pulse facilitation in mouse hippocampal slices. Brain Research, 1560, 10 - 17.

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Horta, R., Aguiar, P., Monteiro, D., Silva, A., & Amarante, J. M. (2014). A facegram for spatial-temporal analysis of facial excursion: Applicability in the microsurgical reanimation of long-standing paralysis and pretransplantation. Journal of Cranio-Maxillofacial Surgery.

Horta, R., Aguiar, P., Silva, P., Monteiro, D., & Amarante, J. M. (2014). Facial disfigurement: Restoration of facial dynamics in a patient with concomitant facial paralysis and blindness. Journal of Reconstructive Microsurgery, 30(3), 207 - 210.

Crespo, T. C., Silva, B., Marques, L., Marcelino, E., et al. (2014). Genetic and biochemical markers in patients with Alzheimer's disease support a concerted systemic iron homeostasis dysregulation. Neurobiology of Aging, 35(4), 777 - 785.

Gonçalves, N. P., Teixeira-Coelho, M., & Saraiva, M. J. (2014). The inflammatory response to sciatic nerve injury in a familial amyloidotic polyneuropathy mouse model. Experimental Neurology, 257, 76 - 87.

Nischwitz, S., Faber, H., Sämann, P. G., Domingues, H. S., et al. (2014). Interferon ?-1a reduces increased interleukin-16 levels in multiple sclerosis patients. Acta Neurologica Scandinavica, 130(1), 46 - 52.

Rothaug, M., Zunke, F., Mazzulli, J. R., Schweizer, M., et al. (2014). LIMP-2 expression is critical for Î²-glucocerebrosidase activity and Î±-synuclein clearance. Proceedings of the National Academy of Sciences of the United States of America, 111(43), 15573 - 15578.

Santos-Antunes, J., Magro, F., & Macedo, G. (2014). Listeria monocytogenes bacteremia and CMV colitis in a patient with Ulcerative Colitis. Journal of Crohn's and Colitis, 8(3), 254 - 255.

Esteves, T., Durr, A., Mundwiller, E., Loureiro, J. L., et al. (2014). Loss of association of REEP2 with membranes leads to hereditary spastic paraplegia. American Journal of Human Genetics, 94(2), 268 - 277.

Sillero, N., Reis, M., Vieira, C. P., Vieira, J., & Morales-Hojas, R. (2014). Niche evolution and thermal adaptation in the temperate species Drosophila americana. Journal of Evolutionary Biology.

Da Silva, T. F., Eira, J., Lopes, A. T., Malheiro, A. R., et al. (2014). Peripheral nervous system plasmalogens regulate Schwann cell differentiation and myelination. Journal of Clinical Investigation, 124(6), 2560 - 2570.

Luz, L. L., Szucs, P., & Safronov, B. V. (2014). Peripherally driven low-threshold inhibitory inputs to lamina I local-circuit and projection neurones: A new circuit for gating pain responses. Journal of Physiology, 592(7), 1519 - 1534.

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Sousa, M., Szucs, P., Lima, D., & Aguiar, P. (2014). The pronociceptive dorsal reticular nucleus contains mostly tonic neurons and shows a high prevalence of spontaneous activity in block preparation. Journal of Neurophysiology, 111(7), 1507 - 1518.

Ferreirinha, P., Dias, J., Correia, A., Pérez-Cabezas, B., et al. (2014). Protective effect of intranasal immunization with Neospora caninum membrane antigens against murine neosporosis established through the gastrointestinal tract. Immunology, 141(2), 256 - 267.

Nazareth, T., Teodósio, R., Porto, G., Gonçalves, L., et al. (2014). Strengthening the perception-assessment tools for dengue prevention: A cross-sectional survey in a temperate region Madeira, Portugal. BMC Public Health, 14(1).

da VG, G., de M, M. A., A, M. S., R, L., et al. (2014). T Cell Activation Regulates CD6 Alternative Splicing by Transcription Dynamics and SRSF1. J Immunol, 193(1).

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Vieira, M., & Saraiva, M. J. (2014). Transthyretin: A multifaceted protein. Biomolecular Concepts, 5(1), 45 - 54.

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Morais-De-Sá, E., & Sunkel, C. (2013). Adherens junctions determine the apical position of the midbody during follicular epithelial cell division. EMBO Reports, 14(8), 696 - 703.

Miranda, C. O., Brites, P., Sousa, M. M., & Teixeira, C. A. (2013). Advances and pitfalls of cell therapy in metabolic leukodystrophies. Cell Transplantation, 22(2), 189 - 204.

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Silva, D. S., Pereira, L. M. G., Moreira, A. R., Ferreira-Da-Silva, F., et al. (2013). The Apoptogenic Toxin AIP56 Is a Metalloprotease A-B Toxin that Cleaves NF-?b P65. PLoS Pathogens, 9(2).

Erzincanli, B., & Sahin, M. (2013). An arbitrary Lagrangian-Eulerian formulation for solving moving boundary problems with large displacements and rotations. Journal of Computational Physics, 255, 660 - 679.

Pereira, S. B., Mota, R., Santos, C. L., De Philippis, R., & Tamagnini, P. (2013). Assembly and export of extracellular polymeric substances (EPS) in cyanobacteria. A phylogenomic approach. Advances in Botanical Research (Vol. 65, pp. 235 - 279).

Mathieu, J., Cauvin, C., Moch, C., Radford, S., et al. (2013). Aurora B and Cyclin B have opposite effects on the timing of cytokinesis abscission in drosophila germ cells and in vertebrate somatic cells. Developmental Cell, 26(3), 250 - 265.

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Huber, R. C., Kolb, A. F., Lillico, S., Carlisle, A., et al. (2013). Behaviour of postnatally growth-impaired mice during malnutrition and after partial weight recovery. Nutritional Neuroscience, 16(3), 125 - 134.

Lima, M., Silva, K., Amaral, I., Magalhães, A., & de Sousa, L. (2013). Beyond behavioural observations: A deeper view through the sensory reactions of children with profound intellectual and multiple disabilities. Child: Care, Health and Development, 39(3), 422 - 431.

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Eamvijarn, A., Gomes, N. M., Dethoup, T., Buaruang, J., et al. (2013). Bioactive meroditerpenes and indole alkaloids from the soil fungus Neosartorya fischeri (KUFC 6344), and the marine-derived fungi Neosartorya laciniosa (KUFC 7896) and Neosartorya tsunodae (KUFC 9213). Tetrahedron, 69(40), 8583 - 8591.

Do Sameiro-Faria, M., Ribeiro, S., Rocha-Pereira, P., Fernandes, J., et al. (2013). Body mass index and resistance to recombinant human erythropoietin therapy in maintenance hemodialysis patients. Renal Failure, 35(10), 1392 - 1398.

Ramos, E. M., Latourelle, J. C., Gillis, T., Mysore, J. S., et al. (2013). Candidate glutamatergic and dopaminergic pathway gene variants do not influence Huntington's disease motor onset. Neurogenetics, 14(3-4), 173 - 179.

Francisco, T., Rodrigues, T. A., Freitas, M. O., Grou, C. P., et al. (2013). A cargo-centered perspective on the PEX5 receptor-mediated peroxisomal protein import pathway. Journal of Biological Chemistry, 288(40), 29151 - 29159.

Barros, J., Damásio, J., Tuna, A., Alves, I., et al. (2013). Cerebellar ataxia, hemiplegic migraine, and related phenotypes due to a CACNA1A missense mutation: 12-year follow-up of a large portuguese family. JAMA Neurology, 70(2), 235 - 240.

Venâncio, C., Antunes, L., Félix, L., Rodrigues, P., et al. (2013). Chronic ketamine administration impairs mitochondrial complex i in the rat liver. Life Sciences, 93(12-14), 464 - 470.

Kohlova, M., Ribeiro, S., Do Sameiro-Faria, M., Rocha-Pereira, P., et al. (2013). Circulating cell-free DNA levels in hemodialysis patients and its association with inflammation, iron metabolism, and rhEPO doses. Hemodialysis International, 17(4), 664 - 667.

Silva, F. S. G., Oliveira, H., Moreiras, A., Fernandes, J. C., et al. (2013). Cytotoxic and genotoxic effects of acitretin, alone or in combination with psoralen-ultraviolet A or narrow-band ultraviolet B-therapy in psoriatic patients. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 753(1), 42 - 47.

Sousa, S., Cardoso, L., Reed, S. G., Reis, A. B., et al. (2013). Development of a Fluorescent Based Immunosensor for the Serodiagnosis of Canine Leishmaniasis Combining Immunomagnetic Separation and Flow Cytometry. PLoS Neglected Tropical Diseases, 7(8).

Monjardino, P., Rocha, S., Tavares, A. C., Fernandes, R., et al. (2013). Development of flange and reticulate wall ingrowths in maize (Zea mays L.) endosperm transfer cells. Protoplasma, 250(2), 495 - 503.

Ferreira, N., Santos, S. A. O., Domingues, M. R. M., Saraiva, M. J., & Almeida, M. R. (2013). Dietary curcumin counteracts extracellular transthyretin deposition: Insights on the mechanism of amyloid inhibition. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1832(1), 39 - 45.

Laforge, M., Limou, S., Harper, F., Casartelli, N., et al. (2013). DRAM Triggers Lysosomal Membrane Permeabilization and Cell Death in CD4+ T Cells Infected with HIV. PLoS Pathogens, 9(5).

Fonseca, N. A., Morales-Hojas, R., Reis, M., Rocha, H., et al. (2013). Drosophila americana as a model species for comparative studies on the molecular basis of phenotypic variation. Genome Biology and Evolution, 5(4), 661 - 679.

Conde, C., Osswald, M., Barbosa, J., Moutinho-Santos, T., et al. (2013). Drosophila Polo regulates the spindle assembly checkpoint through Mps1-dependent BubR1 phosphorylation. EMBO Journal, 32(12), 1761 - 1777.

Ramos, M. A., Sousa, N. R., Franco, A. R., Costa, V., et al. (2013). Effect of diflubenzuron on the development of Pinus pinaster seedlings inoculated with the ectomycorrhizal fungus Pisolithus tinctorius. Environmental Science and Pollution Research, 20(1), 582 - 590.

Amaral, C., Varela, C., Azevedo, M., da Silva, E. T., et al. (2013). Effects of steroidal aromatase inhibitors on sensitive and resistant breast cancer cells: Aromatase inhibition and autophagy. Journal of Steroid Biochemistry and Molecular Biology.

Amaral, I. F., Neiva, I., Ferreira Da Silva, F., Sousa, S. R., et al. (2013). Endothelialization of chitosan porous conduits via immobilization of a recombinant fibronectin fragment (rhFNIII7-10). Acta Biomaterialia, 9(3), 5643 - 5652.

Braunlin, E., Rosenfeld, H., Kampmann, C., Johnson, J., et al. (2013). Enzyme replacement therapy for mucopolysaccharidosis VI: Long-term cardiac effects of galsulfase (Naglazyme®) therapy. Journal of Inherited Metabolic Disease, 36(2), 385 - 394.

Magro, F., Santos-Antunes, J., Albuquerque, A., Vilas-Boas, F., et al. (2013). Epstein-barr virus in inflammatory bowel disease-correlation with different therapeutic regimens. Inflammatory Bowel Diseases, 19(8), 1710 - 1716.

Horta, R., Monteiro, D., Silva, A., Amarante, J. M., & Aguiar, P. (2013). Erratum: Evaluation of a facial transplant candidate with a facegram: A baseline analysis (Plastic and Reconstructive Surgery (2013) 132 (479e-480)). Plastic and Reconstructive Surgery, 132(4), 1040 - 1041.

Silva, T., Adão, R., Nazmi, K., Bolscher, J. G. M., et al. (2013). Erratum: Structural diversity and mode of action on lipid membranes of three lactoferrin candidacidal peptides (Biochimica et Biophysica Acta - Biomembranes (2013) 1828 (1329-1339)). Biochimica et Biophysica Acta - Biomembranes, 1828(11), 2796.

Earnshaw, W. C., Allshire, R. C., Black, B. E., Bloom, K., et al. (2013). Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Research, 21(2), 101 - 106.

Magro, F., Langner, C., Driessen, A., Ensari, A., et al. (2013). European consensus on the histopathology of inflammatory bowel disease. Journal of Crohn's and Colitis, 7(10), 827 - 851.

Aguiar, P., Horta, R., Monteiro, D., Silva, A., & Amarante, J. M. (2013). Evaluation of a facial transplant candidate with a facegram: A baseline analysis. Plastic and Reconstructive Surgery, 132(3), 479e - 480e.

Guedes, A. C., Gião, M. S., Seabra, R., Ferreira, A. C. S., et al. (2013). Evaluation of the antioxidant activity of cell extracts from microalgae. Marine Drugs, 11(4), 1256 - 1270.

Santarém, N., Racine, G., Silvestre, R., Cordeiro-da-Silva, A., & Ouellette, M. (2013). Exoproteome dynamics in Leishmania infantum. Journal of Proteomics, 84, 106 - 118.

Coimbra, S., Oliveira, H., Figueiredo, A., Rocha-Pereira, P., & Santos-Silva, A. (2013). Factors associated with the length of remission of psoriasis vulgaris. Clinical Drug Investigation, 33(11), 855 - 860.

Vilhena, H., Martinez-Díaz, V. L., Cardoso, L., Vieira, L., et al. (2013). Feline vector-borne pathogens in the north and centre of Portugal. Parasites and Vectors, 6(1).

Misumi, Y., Ando, Y., Gonçalves, N. P., & Saraiva, M. J. (2013). Fibroblasts endocytose and degrade transthyretin aggregates in transthyretin-related amyloidosis. Laboratory Investigation, 93(8), 911 - 920.

Mendes, A., Sousa, L., & Paneque, M. (2013). From constraints to opportunities? Provision of psychosocial support in Portuguese oncogenetic counseling services. Journal of Genetic Counseling, 22(6), 771 - 783.

Silva, M. S., Ferreira, A. E. N., Gomes, R., Tomás, A. M., et al. (2013). Glyoxalase Enzymes in Trypanosomatids. In Trypanosomatid Diseases: Molecular Routes to Drug Discovery (pp. 153 - 166).

Coelho, S. C., Rocha, S., Juzenas, P., Sampaio, P., et al. (2013). Gold nanoparticle delivery-enhanced proteasome inhibitor effect in adenocarcinoma cells. Expert Opinion on Drug Delivery, 10(10), 1345 - 1352.

Silva-Gomes, S., Appelberg, R., Larsen, R., Soares, M. P., & Gomes, M. S. (2013). Heme catabolism by heme oxygenase-1 confers host resistance to Mycobacterium infection. Infection and Immunity, 81(7), 2536 - 2545.

Batista, A. R., Sena-Esteves, M., & Saraiva, M. J. (2013). Hepatic production of transthyretin L12P leads to intracellular lysosomal aggregates in a new somatic transgenic mouse model. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1832(8), 1183 - 1193.

Morinha, F., Travassos, P., Seixas, F., Santos, N., et al. (2013). High-resolution melting analysis for bird sexing: A successful approach to molecular sex identification using different biological samples. Molecular Ecology Resources, 13(3), 473 - 483.

Petrakis, I., Mavroeidi, V., Stylianou, K., Andronikidi, E., et al. (2013). Hsf-1 affects podocyte markers NPHS1, NPHS2 and WT1 in a transgenic mouse model of TTRVal30Met-related amyloidosis. Amyloid, 20(3), 164 - 172.

Petrakis, I., Mavroeidi, V., Stylianou, K., Efthymiou, G., et al. (2013). Human TTRV30M localization within podocytes in a transgenic mouse model of transthyretin related amyloidosis: Does the environment play a role?. Transgenic Research, 22(1), 101 - 116.

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Pellegrino, R. M., Coutinho, M., D'Ascola, D., Lopes, A. M., et al. (2012). Two novel mutations in the tmprss6 gene associated with iron-refractory iron-deficiency anaemia (irida) and partial expression in the heterozygous form. British Journal of Haematology, 158(5), 668 - 672.

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Santos, C. L., Correia-Neves, M., Moradas-Ferreira, P., & Mendes, M. V. (2012). A Walk into the LuxR Regulators of Actinobacteria: Phylogenomic Distribution and Functional Diversity. PLoS ONE, 7(10).

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Bettencourt, C., Raposo, M., Kazachkova, N., Cymbron, T., et al. (2011). The APOE ? 2 allele increases the risk of earlier age at onset in Machado-Joseph disease. Archives of Neurology, 68(12), 1580 - 1583.

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Ribeiro, M. M. B., Pinto, A. R. T., Domingues, M. M., Serrano, I., et al. (2011). Chemical conjugation of the neuropeptide kyotorphin and ibuprofen enhances brain targeting and analgesia. Molecular Pharmaceutics, 8(5), 1929 - 1940.

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Magalhães, J., & Saraiva, M. J. (2011). Clusterin overexpression and its possible protective role in transthyretin deposition in familial amyloidotic polyneuropathy. Journal of Neuropathology and Experimental Neurology, 70(12), 1097 - 1106.

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Lopes, V. R., Schmidtke, M., Helena Fernandes, M., Martins, R., & Vasconcelos, V. (2011). Cytotoxicity in L929 fibroblasts and inhibition of herpes simplex virus type 1 Kupka by estuarine cyanobacteria extracts. Toxicology in Vitro, 25(4), 944 - 950.

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Emmel, V. E., Alonso, I., Jardim, L. B., Saraiva-Pereira, M. L., & Sequeiros, J. (2011). Does DNA methylation in the promoter region of the ATXN3 gene modify age at onset in MJD (SCA3) patients?. Clinical Genetics, 79(1), 100 - 102.

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Cardoso-Cruz, H., Sameshima, K., Lima, D., & Galhardo, V. (2011). Dynamics of circadian thalamocortical flow of information during a peripheral neuropathic pain condition. Frontiers in Integrative Neuroscience, 5.

Barata, L., Sousa Silva, M., Schuldt, L., Ferreira, A. E. N., et al. (2011). Enlightening the molecular basis of trypanothione specificity in trypanosomatids: Mutagenesis of Leishmania infantum glyoxalase II. Experimental Parasitology, 129(4), 402 - 408.

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Oliveira, R., Botelho, F., Silva, P., Resende, A., et al. (2011). Exploratory study assessing efficacy and complications of TVT-O, TVT-Secur, and Mini-Arc: Results at 12-month follow-up. European Urology, 59(6), 940 - 944.

Empadinhas, N., Pereira, P. J. B., Albuquerque, L., Costa, J., et al. (2011). Functional and structural characterization of a novel mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity. Molecular Microbiology, 79(1), 76 - 93.

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Oliveira, S. M., Ribeiro, C. A., Cardoso, I., & Saraiva, M. J. (2011). Gender-dependent transthyretin modulation of brain amyloid-? Levels: Evidence from a mouse model of alzheimer's disease. Journal of Alzheimer's Disease, 27(2), 429 - 439.

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Martin, D., Pantoja, C., Fernández-Miñán, A., Valdes-Quezada, C., et al. (2011). Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes. Nature Structural and Molecular Biology, 18(6), 708 - 714.

Melo, P. M., Silva, L. S., Ribeiro, I., Seabra, A. R., & Carvalho, H. G. (2011). Glutamine synthetase is a molecular target of nitric oxide in root nodules of Medicago truncatula and is regulated by tyrosine nitration. Plant Physiology, 157(3), 1505 - 1517.

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Ferreres, F., Figueiredo, R., Bettencourt, S., Carqueijeiro, I., et al. (2011). Identification of phenolic compounds in isolated vacuoles of the medicinal plant Catharanthus roseus and their interaction with vacuolar class III peroxidase: An H 2O 2 affair?. Journal of Experimental Botany, 62(8), 2841 - 2854.

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Coimbra, S., Oliveira, H., Reis, F., Belo, L., et al. (2010). Interleukin (IL)-22, IL-17, IL-23, IL-8, vascular endothelial growth factor and tumour necrosis factor-? levels in patients with psoriasis before, during and after psoralen-ultraviolet A and narrowband ultraviolet B therapy. British Journal of Dermatology, 163(6), 1282 - 1290.

Reis, O., Sousa, S., Camejo, A., Villiers, V., et al. (2010). LapB, a novel Listeria monocytogenes LPXTG surface adhesin, required for entry into eukaryotic cells and virulence. Journal of Infectious Diseases, 202(4), 551 - 562.

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Cardoso, L., Lopes, A. P., Sherry, K., Schallig, H., & Solano-Gallego, L. (2010). Low seroprevalence of Leishmania infantum infection in cats from northern Portugal based on DAT and ELISA. Veterinary Parasitology, 174(1-2), 37 - 42.

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Seabra, A. R., Vieira, C. P., Cullimore, J. V., & Carvalho, H. G. (2010). Medicago truncatula contains a second gene encoding a plastid located glutamine synthetase exclusively expressed in developing seeds. BMC Plant Biology, 10.

Schäfer, M. A., Mazzi, D., Klappert, K., Kauranen, H., et al. (2010). A microsatellite linkage map for Drosophila montana shows large variation in recombination rates, and a courtship song trait maps to an area of low recombination. Journal of Evolutionary Biology, 23(3), 518 - 527.

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Santos, C., Fregel, R., Cabrera, V. M., González, A. M., et al. (2010). Mitochondrial DNA patterns in the macaronesia Islands: Variation within and among archipelagos. American Journal of Physical Anthropology, 141(4), 610 - 619.

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Reis, M. I. R., Costa-Ramos, C., do Vale, A., & dos Santos, N. M. S. (2010). Molecular cloning of sea bass (Dicentrarchus labrax L.) caspase-8 gene and its involvement in Photobacterium damselae ssp. piscicida triggered apoptosis. Fish and Shellfish Immunology, 29(1), 58 - 65.

Santos, M., Summavielle, T., Teixeira-Castro, A., Silva-Fernandes, A., et al. (2010). Monoamine deficits in the brain of methyl-CpG binding protein 2 null mice suggest the involvement of the cerebral cortex in early stages of Rett syndrome. Neuroscience, 170(2), 453 - 467.

Luz, L. L., Szucs, P., Pinho, R., & Safronov, B. V. (2010). Monosynaptic excitatory inputs to spinal lamina I anterolateral-tract-projecting neurons from neighbouring lamina I neurons. Journal of Physiology, 588(22), 4489 - 4505.

Pinto, V., Szucs, P., Lima, D., & Safronov, B. V. (2010). Multisegmental A?- and C-fiber input to neurons in lamina I and the lateral spinal nucleus. Journal of Neuroscience, 30(6), 2384 - 2395.

Franquinho, F., Liz, M. A., Nunes, A. F., Neto, E., et al. (2010). Neuropeptide y and osteoblast differentiation - The balance between the neuro-osteogenic network and local control: Review Article. FEBS Journal, 277(18), 3664 - 3674.

Nunes, A. F., Liz, M. A., Franquinho, F., Teixeira, L., et al. (2010). Neuropeptide y expression and function during osteoblast differentiation - Insights from transthyretin knockout mice. FEBS Journal, 277(1), 263 - 275.

Pereira, R., Costa, E., Gonçalves, M., Miranda, V., et al. (2010). Neutrophil and monocyte activation in chronic kidney disease patients under hemodialysis and its relationship with resistance to recombinant human erythropoietin and to the hemodialysis procedure. Hemodialysis International, 14(3), 295 - 301.

Silva, M. T. (2010). Neutrophils and macrophages work in concert as inducers and effectors of adaptive immunity against extracellular and intracellular microbial pathogens. Journal of Leukocyte Biology, 87(5), 805 - 813.

Aguiar, P., Sousa, M., & Lima, D. (2010). NMDA channels together with L-type calcium currents and calcium-activated nonspecific cationic currents are sufficient to generate windup in WDR neurons. Journal of Neurophysiology, 104(2), 1155 - 1166.

Dutra, I. F., Bettencourt, B. F., Fialho, R. N., Couto, A. R., et al. (2010). Novel fast reverse transcriptase PCR assay for molecular detection of human influenza A (H1N1) virus. Journal of Clinical Microbiology, 48(5), 1985 - 1986.

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Özçelik, M., Cotter, L., Jacob, C., Pereira, J. A., et al. (2010). Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves. Journal of Neuroscience, 30(11), 4120 - 4131.

Silveira, A. P., Gonçalves, J., Sequeira, T., Ribeiro, C., et al. (2010). Patient reported outcomes in head and neck cancer: Selecting instruments for quality of life integration in clinical protocols. Head and Neck Oncology, 2(1).

Pereira, D. M., Ferreres, F., Oliveira, J. M. A., Gaspar, L., et al. (2010). Pharmacological effects of Catharanthus roseus root alkaloids in acetylcholinesterase inhibition and cholinergic neurotransmission. Phytomedicine, 17(8-9), 646 - 652.

Ferreira-Gomes, J., Adães, S., Sarkander, J., & Castro-Lopes, J. M. (2010). Phenotypic alterations of neurons that innervate osteoarthritic joints in rats. Arthritis and Rheumatism, 62(12), 3677 - 3685.

Santos, J. S., Fonseca, N. A., Vieira, C. P., Vieira, J., & Casares, F. (2010). Phylogeny of the teashirt-related zinc finger (tshz) gene family and analysis of the developmental expression of tshz2 and tshz3b in the zebrafish. Developmental Dynamics, 239(3), 1010 - 1018.

Teixeira, L., Botelho, A. S., Mesquita, S. D., Correia, A., et al. (2010). Plasmacytoid and conventional dendritic cells are early producers of IL-12 in Neospora caninum-infected mice. Immunology and Cell Biology, 88(1), 79 - 86.

Paiva-Martins, F., Fernandes, J., Santos, V., Silva, L., et al. (2010). Powerful protective role of 3,4-dihydroxyphenylethanol-elenolic acid dialdehyde against erythrocyte oxidative-Lnduced hemolysis. Journal of Agricultural and Food Chemistry, 58(1), 135 - 140.

Santos, R., Oliveira, J., Vieira, E., Coelho, T., et al. (2010). Private dysferlin exon skipping mutation (c.5492G > A) with a founder effect reveals further alternative splicing involving exons 49-51. Journal of Human Genetics, 55(8), 546 - 549.

Saraiva, A. M., Cardoso, I., Saraiva, M. J., Tauer, K., et al. (2010). Randomization of Amyloid-?-Peptide(1-42) Conformation by Sulfonated and Sulfated Nanoparticles Reduces Aggregation and Cytotoxicity. Macromolecular Bioscience, 10(10), 1152 - 1163.

Teixeira, A. M., Garrido, P., Santos, P., Alves, R., et al. (2010). Recombinant human erythropoietin treatment protects the cardio-renal axis in a model of moderate chronic renal failure. Renal Failure, 32(9), 1073 - 1080.

Ferrer, L., Baneth, G., Bourdeau, P., Koutinas, A., et al. (2010). Response to the letter: "Some remarks about the LeishVet directions for the treatment of canine leishmaniosis". Veterinary Parasitology, 169(3-4), 418 - 420.

Ferreres, F., Pereira, D. M., Valentão, P., Oliveira, J. M. A., et al. (2010). Simple and reproducible HPLC-DAD-ESI-MS/MS analysis of alkaloids in Catharanthus roseus roots. Journal of Pharmaceutical and Biomedical Analysis, 51(1), 65 - 69.

Cardoso, I., Martins, D., Ribeiro, T., Merlini, G., & Saraiva, M. J. (2010). Synergy of combined Doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: Studies in FAP mouse models. Journal of Translational Medicine, 8.

Pinto, R., Lopes, T., Frias, B., Silva, A., et al. (2010). Trigonal injection of botulinum toxin A in patients with refractory bladder pain syndrome/interstitial cystitis. Journal of Urology, 184(4), 1364 - 1365.

Pinto, R., Lopes, T., Frias, B., Silva, A., et al. (2010). Trigonal injection of botulinum toxin A in patients with refractory bladder pain syndrome/interstitial cystitis. European Urology, 58(3), 360 - 365.

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Silva, M. T. (2010). When two is better than one: Macrophages and neutrophils work in concert in innate immunity as complementary and cooperative partners of a myeloid phagocyte system. Journal of Leukocyte Biology, 87(1), 93 - 106.

Magalhães, J., Santos, S. D., & Saraiva, M. J. (2010). ?B-crystallin (HspB5) in familial amyloidotic polyneuropathy. International Journal of Experimental Pathology, 91(6), 515 - 521.

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Alves, E., Binienda, Z., Carvalho, F., Alves, C. J., et al. (2009). Acetyl-l-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain. Neuroscience, 158(2), 514 - 523.

Queirós, F., Fontes, N., Silva, P., Almeida, D., et al. (2009). Activity of tonoplast proton pumps and Na +/H + exchange in potato cell cultures is modulated by salt. Journal of Experimental Botany, 60(4), 1363 - 1374.

Szucs, P., Pinto, V., & Safronov, B. V. (2009). Advanced technique of infrared LED imaging of unstained cells and intracellular structures in isolated spinal cord, brainstem, ganglia and cerebellum. Journal of Neuroscience Methods, 177(2), 369 - 380.

Spínola, C., Bruges-Armas, J., Pereira, C., Brehm, A., & Spínola, H. (2009). Alpha-1-antitrypsin deficiency in Madeira (Portugal): The highest prevalence in the world. Respiratory Medicine, 103(10), 1498 - 1502.

Almeida, T., Alonso, I., Martins, S., Ramos, E. M., et al. (2009). Ancestral origin of the ATTCT repeat expansion in spinocerebellar ataxia type 10 (SCA10). PLoS ONE, 4(2).

Vilela, S. M. F., Santos, D. J. S. L., Félix, L., Almeida, J. M., et al. (2009). Are fentanyl and remifentanil safe opioids for rat brain mitochondrial bioenergetics?. Mitochondrion, 9(4), 247 - 253.

Anheim, M., Monga, B., Fleury, M., Charles, P., et al. (2009). Ataxia with oculomotor apraxia type 2: Clinical, biological and genotype/phenotype correlation study of a cohort of 90 patients. Brain, 132(10), 2688 - 2698.

Silva, A., Pereira, J., Oliveira, C. R., Relvas, J. B., & Rego, A. C. (2009). BDNF and extracellular matrix regulate differentiation of mice neurosphere-derived cells into a GABAergic neuronal phenotype. Journal of Neuroscience Research, 87(9), 1986 - 1996.

Ferreira, N., Cardoso, I., Domingues, M. R., Vitorino, R., et al. (2009). Binding of epigallocatechin-3-gallate to transthyretin modulates its amyloidogenicity. FEBS Letters, 583(22), 3569 - 3576.

Sousa, E., Paiva, A., Nazareth, N., Gales, L., et al. (2009). Bromoalkoxyxanthones as promising antitumor agents: Synthesis, crystal structure and effect on human tumor cell lines. European Journal of Medicinal Chemistry, 44(9), 3830 - 3835.

Portaels, F., Silva, M. T., & Meyers, W. M. (2009). Buruli ulcer. Clinics in Dermatology, 27(3), 291 - 305.

Oliveira, M. J., Costa, A. M., Costa, A. C., Ferreira, R. M., et al. (2009). CagA associates with c-met, E-cadherin, and p120catenin in a multiproteic complex that suppresses helicobacter pylori-induced cell-invasive phenotype. Journal of Infectious Diseases, 200(5), 745 - 755.

Vieira-Coelho, M. A., Serrão, M. P., Afonso, J., Pinto, C. E., & Moura, E. (2009). Catecholamine synthesis and metabolism in the central nervous system of mice lacking ? 2-adrenoceptor subtypes: RESEARCH PAPER. British Journal of Pharmacology, 158(3), 726 - 737.

Fleming, C. E., Mar, F. M., Franquinho, F., & Sousa, M. M. (2009). Chapter 17 Transthyretin. An Enhancer of Nerve Regeneration. International Review of Neurobiology (Vol. 87, pp. 337 - 346).

Kim, S., Silva, C., Zille, A., Lopez, C., et al. (2009). Characterisation of enzymatically oxidised lignosulfonates and their application on lignocellulosic fabrics. Polymer International, 58(8), 863 - 868.

Pye, S. R., Tobias, J., Silman, A. J., Reeve, J., & O'Neill, T. W. (2009). Childhood fractures do not predict future fractures: Results from the European prospective osteoporosis study. Journal of Bone and Mineral Research, 24(7), 1314 - 1318.

Coimbra, S., Oliveira, H., Reis, F., Belo, L., et al. (2009). Circulating levels of adiponectin, oxidized LDL and C-reactive protein in Portuguese patients with psoriasis vulgaris, according to body mass index, severity and duration of the disease. Journal of Dermatological Science, 55(3), 202 - 204.

Pittman, A. M., Naranjo, S., Webb, E., Broderick, P., et al. (2009). The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression. Genome Research, 19(6), 987 - 993.

Flórido, M., Borges, M., Rodrigues, P., Vale-Costa, S., et al. (2009). Constitutive expression of Bcl-2 in the haematopoietic compartment alters the metabolism of iron and increases resistance to mycobacterial infection. Clinical and Experimental Immunology, 156(1), 61 - 68.

Silvestre, R., Silva, A. M., Cordeiro-da-Silva, A., & Ouaissi, A. (2009). The contribution of Toll-like receptor 2 to the innate recognition of a Leishmania infantum silent information regulator 2 protein. Immunology, 128(4), 484 - 499.

Sousa, S. I. V., Martins, F. G., Pereira, M. C., Alvim-Ferraz, M. C. M., et al. (2009). Corrigendum to "Influence of atmospheric ozone, PM10 and meteorological factors on the concentration of airborne pollen and fungal spore" [Atmos. Environ. 42 (2008) 7452-7464] (DOI:10.1016/j.atmosenv.2008.06.004). Atmospheric Environment, 43(13), 2228.

Saraiva, A., Ramos, M. F., Barandela, T., Sousa, J. A., & Rodrigues, P. N. (2009). Cryptosporidium sp. (Apicomplexa) from cultured turbot Psetta maxima. Bulletin of the European Association of Fish Pathologists, 29(1), 34 - 36.

Seabra, A. R., Carvalho, H., & Pereira, P. J. B. (2009). Crystallization and preliminary crystallographic characterization of glutamine synthetase from Medicago truncatula. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 65(12), 1309 - 1312.

Pinto, M. P., Grou, C. P., Fransen, M., Sá-Miranda, C., & Azevedo, J. E. (2009). The cytosolic domain of PEX3, a protein involved in the biogenesis of peroxisomes, binds membrane lipids. Biochimica et Biophysica Acta - Molecular Cell Research, 1793(11), 1669 - 1675.

Romao, S., Castro, H., Sousa, C., Carvalho, S., & Tomás, A. M. (2009). The cytosolic tryparedoxin of Leishmania infantum is essential for parasite survival. International Journal for Parasitology, 39(6), 703 - 711.

Song, R., Duarte, T. L., Almeida, G. M., Farmer, P. B., et al. (2009). Cytotoxicity and gene expression profiling of two hydroxylated polybrominated diphenyl ethers in human H295R adrenocortical carcinoma cells. Toxicology Letters, 185(1), 23 - 31.

Rocha, S., Cardoso, I., Börner, H., Pereira, M. C., et al. (2009). Design and biological activity of ?-sheet breaker peptide conjugates. Biochemical and Biophysical Research Communications, 380(2), 397 - 401.

Patch, C., Sequeiros, J., & Cornel, M. C. (2009). Direct to consumer genetic tests. European Journal of Human Genetics, 17(9), 1111.

Solano-Gallego, L., Koutinas, A., Miró, G., Cardoso, L., et al. (2009). Directions for the diagnosis, clinical staging, treatment and prevention of canine leishmaniosis. Veterinary Parasitology, 165(1-2), 1 - 18.

Albuquerque, P., Mendes, M. V., Santos, C. L., Moradas-Ferreira, P., & Tavares, F. (2009). DNA signature-based approaches for bacterial detection and identification. Science of the Total Environment, 407(12), 3641 - 3651.

Reis, R., Feijão, T., Gouveia, S., Pereira, A. J., et al. (2009). Dynein and Mast/Orbit/CLASP have antagonistic roles in regulating kinetochore-microtubule plus-end dynamics. Journal of Cell Science, 122(14), 2543 - 2553.

Alves, E., Summavielle, T., Alves, C. J., Custódio, J. B. A., et al. (2009). Ecstasy-induced oxidative stress to adolescent rat brain mitochondria in vivo: Influence of monoamine oxidase type A. Addiction Biology, 14(2), 185 - 193.

Moura, E., Afonso, J., Serrão, M. P., & Vieira-Coelho, M. A. (2009). Effect of clonidine on tyrosine hydroxylase activity in the adrenal medulla and brain of spontaneously hypertensive rats. Basic and Clinical Pharmacology and Toxicology, 104(2), 113 - 121.

Costa, E., Rocha, S., Rocha-Pereira, P., Reis, F., et al. (2009). Effect of hemodialysis procedure in prohepcidin serum levels in regular hemodialysis patients. Clinical Nephrology, 71(2), 233 - 235.

Paiva-Martins, F., Fernandes, J., Rocha, S., Nascimento, H., et al. (2009). Effects of olive oil polyphenols on erythrocyte oxidative damage. Molecular Nutrition and Food Research, 53(5), 609 - 616.

Catarino, C., Rebelo, I., Belo, L., Rocha-Pereira, P., et al. (2009). Erythrocyte changes in preeclampsia: Relationship between maternal and cord blood erythrocyte damage. Journal of Perinatal Medicine, 37(1), 19 - 27.

Temudo, T., Rios, M., Prior, C., Carrilho, I., et al. (2009). Evaluation of CSF neurotransmitters and folate in 25 patients with Rett disorder and effects of treatment. Brain and Development, 31(1), 46 - 51.

Silvestre, R., Santarém, N., Teixeira, L., Cunha, J., et al. (2009). Evaluation of Leishmania species reactivity in human serologic diagnosis of leishmaniasis. American Journal of Tropical Medicine and Hygiene, 81(2), 202 - 208.

Teixeira de Lemos, E., Reis, F., Baptista, S., Pinto, R., et al. (2009). Exercise training decreases proinflammatory profile in Zucker diabetic (type 2) fatty rats. Nutrition, 25(3), 330 - 339.

Lemos, C., Castro, M. - J., Barros, J., Sequeiros, J., et al. (2009). Familial clustering of migraine: Further evidence from a portuguese study. Headache, 49(3), 404 - 411.

Catarino, C., Rebelo, I., Belo, L., Rocha, S., et al. (2009). Fetal and maternal angiogenic/anti-angiogenic factors in normal and preeclamptic pregnancy. Growth Factors, 27(6), 345 - 351.

Oliveira, A. P., Valentão, P., Pereira, J. A., Silva, B. M., et al. (2009). Ficus carica L.: Metabolic and biological screening. Food and Chemical Toxicology, 47(11), 2841 - 2846.

Castro, M. - J., Stam, A. H., Lemos, C., De Vries, B., et al. (2009). First mutation in the voltage-gated NaV1.1 subunit gene SCN1A with co-occurring familial hemiplegic migraine and epilepsy. Cephalalgia, 29(3), 308 - 313.

Santos, C., Alvarez, L., Aluja, M. P., Bruges-Armas, J., & Lima, M. (2009). Genetic structure of the Azores Islands: a study using 15 autosomal short tandem repeat loci. Collegium antropologicum, 33(4), 991 - 999.

Carvalho, S., Cruz, T., Santarém, N., Castro, H., et al. (2009). Heme as a source of iron to Leishmania infantum amastigotes. Acta Tropica, 109(2), 131 - 135.

Costa, E., Swinkels, D. W., Laarakkers, C. M., Rocha-Pereira, P., et al. (2009). Hepcidin serum levels and resistance to recombinant human erythropoietin therapy in haemodialysis patients. Acta Haematologica, 122(4), 226 - 229.

GutiéRrez, J., López Núñez-Flores, M. J., Gómez-Ros, L. V., Novo Uzal, E., et al. (2009). Hormonal regulation of the basic peroxidase isoenzyme from Zinnia elegans. Planta, 230(4), 767 - 778.

Pina, S., Barandela, T., Santos, M. J., Russell-Pinto, F., & Rodrigues, P. (2009). Identification and description of bucephalus minimus (Digenea: Bucephalidae) life cycle in Portugal: Morphological, histopathological, and molecular data. Journal of Parasitology, 95(2), 353 - 359.

Seabra, R., Santos, A., Pereira, S., Moradas-Ferreira, P., & Tamagnini, P. (2009). Immunolocalization of the uptake hydrogenase in the marine cyanobacterium Lyngbya majuscula CCAP 1446/4 and two Nostoc strains. FEMS Microbiology Letters, 292(1), 57 - 62.

Simões, J., Madureira, P., Nunes, F. M., Domingues, M. R., et al. (2009). Immunostimulatory properties of coffee mannans. Molecular Nutrition and Food Research, 53(8), 1036 - 1043.

Camejo, A., Buchrieser, C., Couvé, E., Carvalho, F., et al. (2009). In vivo transcriptional profiling of Listeria monocytogenes and mutagenesis identify new virulence factors involved in infection. PLoS Pathogens, 5(5).

Nunes, C. S., Ferreira, D. A., Antunes, L., Lobo, F., et al. (2009). Individual effect-site concentrations of propofol at return of consciousness are related to the concentrations at loss of consciousness and age in neurosurgical patients. Journal of Clinical Anesthesia, 21(1), 3 - 8.

Pereira, J. A., Benninger, Y., Baumann, R., Gonçalves, A. F., et al. (2009). Integrin-linked kinase is required for radial sorting of axons and schwann cell remyelination in the peripheral nervous system. Journal of Cell Biology, 185(1), 147 - 161.

Guimarães, M., Oliveira, R., Pinto, R., Soares, A., et al. (2009). Intermediate-term results, up to 4 years, of a bone-anchored male perineal sling for treating male stress urinary incontinence after prostate surgery. BJU International, 103(4), 500 - 504.

Almeida, L., Vaz-Da-Silva, M., Coelho, R., Albino-Teixeira, A., & Soares-Da-Silva, P. (2009). Interpersonal values of healthy subjects who volunteer for phase I clinical trials. Pharmaceutical Medicine, 23(5-6), 299 - 303.

Silva, J., Pinto, R., Carvalho, T., Botelho, F., et al. (2009). Intraprostatic Botulinum Toxin Type A injection in patients with benign prostatic enlargement: Duration of the effect of a single treatment. BMC Urology, 9(1).

Mairal, T., Nieto, J., Pinto, M., Almeida, M. R., et al. (2009). Iodine atoms: a new molecular feature for the design of potent transthyretin fibrillogenesis inhibitors. PLoS ONE, 4(1).

Mairal, T., Nieto, J., Pinto, M., Almeida, M. R., et al. (2009). Iodine atoms: A new molecular feature for the design of potent transthyretin fibrillogenesis inhibitors. PLoS ONE, 4(1).

González, A., Quirante, J., Nieto, J., Almeida, M. R., et al. (2009). Isatin derivatives, a novel class of transthyretin fibrillogenesis inhibitors. Bioorganic and Medicinal Chemistry Letters, 19(17), 5270 - 5273.

Rocha, S., Costa, E., Coimbra, S., Nascimento, H., et al. (2009). Linkage of cytosolic peroxiredoxin 2 to erythrocyte membrane imposed by hydrogen peroxide-induced oxidative stress. Blood Cells, Molecules, and Diseases, 43(1), 68 - 73.

Nascimento, H., Silva, L. L., Lourenço, P., Vieira, E., et al. (2009). Lipoprotein(a) levels in obese portuguese children and adolescents: Contribution of the pentanucleotide repeat (TTTTA)n polymorphism in the apolipoprotein(a) gene. Archives of Pediatrics and Adolescent Medicine, 163(4), 393 - 394.

Alencastre, I. S., Rodrigues, T. A., Grou, C. P., Fransen, M., et al. (2009). Mapping the cargo protein membrane translocation step into the PEX5 cycling pathway. Journal of Biological Chemistry, 284(40), 27243 - 27251.

Silva, J., Pinto, R., Carvallho, T., Coelho, A., et al. (2009). Mechanisms of Prostate Atrophy after Glandular Botulinum Neurotoxin Type A Injection: An Experimental Study in the Rat. European Urology, 56(1), 134 - 141.

Franciscon, E., Zille, A., Fantinatti-Garboggini, F., Silva, I. S., et al. (2009). Microaerophilic-aerobic sequential decolourization/biodegradation of textile azo dyes by a facultative Klebsiella sp. strain VN-31. Process Biochemistry, 44(4), 446 - 452.

Gonçalves, C. M., Castro, M. A. A., Henriques, T., Oliveira, M. I., et al. (2009). Molecular cloning and analysis of SSc5D, a new member of the scavenger receptor cysteine-rich superfamily. Molecular Immunology, 46(13), 2585 - 2596.

Maffini, S., Maia, A. R. R., Manning, A. L., Maliga, Z., et al. (2009). Motor-Independent Targeting of CLASPs to Kinetochores by CENP-E Promotes Microtubule Turnover and Poleward Flux. Current Biology, 19(18), 1566 - 1572.

Rodrigues, L. G., Ferraz, M. J., Rodrigues, D., Pais-Vieira, M., et al. (2009). Neurophysiological, behavioral and morphological abnormalities in the Fabry knockout mice. Neurobiology of Disease, 33(1), 48 - 56.

Oliveira-Maia, A. J., Stapleton-Kotloski, J. R., Lyall, V., Phan, T. - H. T., et al. (2009). Nicotine activates TRPM5-dependent and independent taste pathways. Proceedings of the National Academy of Sciences of the United States of America, 106(5), 1596 - 1601.

Loureiro, J. L., Miller-Fleming, L., Thieleke-Matos, C., Magalhães, P., et al. (2009). Novel SPG3A and SPG4 mutations in dominant spastic paraplegia families. Acta Neurologica Scandinavica, 119(2), 113 - 118.

Teixeira, L., Sousa, D. M., Nunes, A. F., Sousa, M. M., et al. (2009). NPY revealed as a critical modulator of osteoblast function in vitro: New insights into the role of Y1 and Y2 receptors. Journal of Cellular Biochemistry, 107(5), 908 - 916.

Dinis, M., Tavares, D., Veiga-Malta, I., Fonseca, A. J. M. M., et al. (2009). Oral therapeutic vaccination with Streptococcus sobrinus recombinant enolase confers protection against dental caries in rats. Journal of Infectious Diseases, 199(1), 116 - 123.

Seixas, D., Galhardo, V., Sá, M. J., Guimarães, J., & Lima, D. (2009). Pain in multiple sclerosis: Characterization of a Portuguese population of 85 patients. Dor na esclerose múltipla: Caracterização de uma população Portuguesa de 85 doentesActa Medica Portuguesa, 22(3), 233 - 240.

Magalhães-Sant'Ana, M., Sanøe, P., & Olsson, I. A. S. (2009). Painful dilemmas: The ethics of animal-based pain research. Animal Welfare, 18(1), 49 - 63.

Fonseca, N. A., Srinivasan, A., Silva, F., & Camacho, R. (2009). Parallel ILP for distributed-memory architectures. Machine Learning, 74(3), 257 - 279.

Silva, M. T., Portaels, F., & Pedrosa, J. (2009). Pathogenetic mechanisms of the intracellular parasite Mycobacterium ulcerans leading to Buruli ulcer. The Lancet Infectious Diseases, 9(11), 699 - 710.

Grou, C. P., Carvalho, A. F., Pinto, M. P., Alencastre, I. S., et al. (2009). The peroxisomal protein import machinery - A case report of transient ubiquitination with a new flavor. Cellular and Molecular Life Sciences, 66(2), 254 - 262.

Almeida, L., Vaz-Da-Silva, M., Falcão, A., Soares, E., et al. (2009). Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers. Molecular Nutrition and Food Research, 53(SUPPL. 1), S7 - S15.

Beetz, N., Harrison, M. D., Brede, M., Zong, X., et al. (2009). Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice. Journal of Clinical Investigation, 119(12), 3597 - 3612.

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Silvestre, R., Santarém, N., Tavares, J., Silva, A. M., & Cordeiro-da-Silva, A. (2009). Recognition of Leishmania parasites by innate immunity. Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, 9(2), 106 - 127.

Ferreira, D., Stal, L. J., Moradas-Ferreira, P., Mendes, M. V., & Tamagnini, P. (2009). The relation between N2 fixation and H2 metabolism in the marine filamentous nonheterocystous cyanobacterium lyngbya aestuarii CCY 9616. Journal of Phycology, 45(4), 898 - 905.

Cruz, F., Silva, J., Pinto, R., Carvallho, T., et al. (2009). Reply to Tomasz Drewa, Zbigniew Wolski and Janusz Tyloch's Letter to the Editor re: João Silva, Rui Pinto, Tiago Carvallho, et al. Mechanisms of Prostate Atrophy after Glandular Botulinum Neurotoxin Type A Injection: An Experimental Study in the Rat. Eur. European Urology, 56(5), e28 - e29.

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Fialho, R. N., Martins, L., Pinheiro, J. P., Bettencourt, B. F., et al. (2009). Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis. Human Immunology, 70(11), 915 - 920.

Paneque, M., Lemos, C., Sousa, A., Velázquez, L., et al. (2009). Role of the disease in the psychological impact of pre-symptomatic testing for SCA2 and FAP ATTRV30M: Experience with the disease, kinship and gender of the transmitting parent. Journal of Genetic Counseling, 18(5), 483 - 493.

Martins, T., Maia, A. F., Steffensen, S., & Sunkel, C. E. (2009). Sgt1, a co-chaperone of Hsp90 stabilizes Polo and is required for centrosome organization. EMBO Journal, 28(3), 234 - 247.

Martins, T., & Sunke, C. E. (2009). Sgt1 plays polo during cell division. Cell Cycle, 8(8), 1110 - 1111.

Oliveira, R., Silva, A., Pinto, R., Silva, J., et al. (2009). Short-term assessment of a tension-free vaginal tape for treating female stress urinary incontinence. BJU International, 104(2), 225 - 228.

Marques, J. M., Alonso, I., Santos, C., Silveira, I., & Olsson, I. A. S. (2009). The spatial learning phenotype of heterozygous leaner mice is robust to systematic variation of the housing environment. Comparative Medicine, 59(2), 129 - 138.

Lince-Faria, M., Maffini, S., Orr, B., Ding, Y., et al. (2009). Spatiotemporal control of mitosis by the conserved spindle matrix protein megator. Journal of Cell Biology, 184(5), 647 - 657.

Fuchs, S., Herzog, D., Sumara, G., Büchmann-Møller, S., et al. (2009). Stage-Specific Control of Neural Crest Stem Cell Proliferation by the Small Rho GTPases Cdc42 and Rac1. Cell Stem Cell, 4(3), 236 - 247.

Liz, M. A., Fleming, C. E., Nunes, A. F., Almeida, M. R., et al. (2009). Substrate specificity of transthyretin: Identification of natural substrates in the nervous system. Biochemical Journal, 419(2), 467 - 474.

Matos, L., Stevenson, D., Gomes, F., Silva-carvalho, J. L., & Almeida, H. (2009). Superoxide dismutase expression in human cumulus oophorus cells. Molecular Human Reproduction, 15(7), 411 - 419.

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Santos, S. F. A., Luz, L. L., Szucs, P., Lima, D., et al. (2009). Transmission efficacy and plasticity in glutamatergic synapses formed by excitatory interneurons of the substantia gelatinosa in the rat spinal cord. PLoS ONE, 4(11).

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Fleming, C. E., Mar, F. M., Franquinho, F., Saraiva, M. J., & Sousa, M. M. (2009). Transthyretin internalization by sensory neurons is megalin mediated and necessary for its neuritogenic activity. Journal of Neuroscience, 29(10), 3220 - 3232.

Nunes, A. F., Montero, M., Franquinho, F., Santos, S. D., et al. (2009). Transthyretin knockout mice display decreased susceptibility to AMPA-induced neurodegeneration. Neurochemistry International, 55(7), 454 - 457.

Fleming, C. E., Nunes, A. F., & Sousa, M. M. (2009). Transthyretin: More than meets the eye. Progress in Neurobiology, 89(3), 266 - 276.

Do Amaral, B., Coelho, T., Sousa, A., & Guimarães, A. (2009). Usefulness of labial salivary gland biopsy in familial amyloid polyneuropathy Portuguese type. Amyloid, 16(4), 232 - 238.

Caldeira, J., Pereira, P. S., Suriano, G., & Casares, F. (2009). Using fruitflies to help understand the molecular mechanisms of human hereditary diffuse gastric cancer. International Journal of Developmental Biology, 53(8-10), 1557 - 1561.

Guedes De Pinho, P., Gonçalves, R. F., Valentão, P., Pereira, D. M., et al. (2009). Volatile composition of Catharanthus roseus (L.) G. Don using solid-phase microextraction and gas chromatography/mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 49(3), 674 - 685.

Bouissou, A., Vérollet, C., Sousa, A., Sampaio, P., et al. (2009). ?-Tubulin ring complexes regulate microtubule plus end dynamics. Journal of Cell Biology, 187(3), 327 - 334.

Marinho, J., Pedro, M., Pinto, D. C. G. A., Silva, A. M. S., et al. (2008). 4?-Methoxy-2-styrylchromone a novel microtubule-stabilizing antimitotic agent. Biochemical Pharmacology, 75(4), 826 - 835.

Quintela, T., Alves, C. H., Gonçalves, I., Baltazar, G., et al. (2008). 5?-dihydrotestosterone up-regulates transthyretin levels in mice and rat choroid plexus via an androgen receptor independent pathway. Brain Research, 1229, 18 - 26.

Díaz-Peña, R., Blanco-Gelaz, M. A., Suárez-Álvarez, B., Martínez-Borra, J., et al. (2008). Activating KIR genes are associated with ankylosing spondylitis in Asian populations. Human Immunology, 69(7), 437 - 442.

Santos, S. D., Magalhães, J., & Saraiva, M. J. (2008). Activation of the heat shock response in familial amyloidotic polyneuropathy. Journal of Neuropathology and Experimental Neurology, 67(5), 449 - 455.

Almeida, L., Coelho, R., Albino-Teixeira, A., & Soares-Da-Silva, P. (2008). Adverse non-drug-related complaints by healthy volunteers in Phase I studies compared to the healthy general population. International Journal of Clinical Pharmacology and Therapeutics, 46(11), 574 - 583.

Borges, O., Silva, M., de Sousa, A., Borchard, G., et al. (2008). Alginate coated chitosan nanoparticles are an effective subcutaneous adjuvant for hepatitis B surface antigen. International Immunopharmacology, 8(13-14), 1773 - 1780.

Costa, E., Rocha, S., Rocha-Pereira, P., Castro, E., et al. (2008). Altered erythrocyte membrane protein composition in chronic kidney disease stage 5 patients under haemodialysis and recombinant human erythropoietin therapy. Blood Purification, 26(3), 267 - 273.

Santos, S. D., Costa, R., Teixeira, P. F., Gottesman, M., et al. (2008). Amyloidogenic properties of transthyretin-like protein (TLP) from Escherichia coli. FEBS Letters, 582(19), 2893 - 2898.

Sabugosa-Madeira, B., Ribeiro, H., Cunha, M., & Abreu, I. (2008). Anemophilous and entomophilous pollen flows of Castanea sativa in the Northeast of Portugal. Acta Horticulturae (Vol. 784, pp. 133 - 136).

Olsson, I. A. S., Hansen, A. K., & Sandøe, P. (2008). Animal welfare and the refinement of neuroscience research methods - A case study of Huntington's disease models. Laboratory Animals, 42(3), 277 - 283.

Balreira, A., MacEdo, M. F., Girão, C., Rodrigues, L. G., et al. (2008). Anomalies in conventional T and invariant natural killer T-cell populations in Fabry mice but not in Fabry patients. British Journal of Haematology, 143(4), 601 - 604.

Macedo, B., Batista, A. R., Ferreira, N., Almeida, M. R., & Saraiva, M. J. (2008). Anti-apoptotic treatment reduces transthyretin deposition in a transgenic mouse model of Familial Amyloidotic Polyneuropathy. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1782(9), 517 - 522.

Temudo, T., Freitas, P., Sequeiros, J., MacIel, P., & Oliveira, G. (2008). Atypical stereotypies and vocal ties in rett syndrome: An illustrative case. Movement Disorders, 23(4), 622 - 623.

Marques, S., Silva, E., Kraft, C., Carvalheira, J., et al. (2008). Bovine mastitis associated with Prototheca blaschkeae. Journal of Clinical Microbiology, 46(6), 1941 - 1945.

Ferro, A., Castro, M. - J., Lemos, C., Santos, M., et al. (2008). The C677T polymorphism in MTHFR is not associated with migraine in Portugal. Disease Markers, 25(2), 107 - 113.

Baneth, G., Koutinas, A. F., Solano-Gallego, L., Bourdeau, P., & Ferrer, L. (2008). Canine leishmaniosis - new concepts and insights on an expanding zoonosis: part one. Trends in Parasitology, 24(7), 324 - 330.

Silva, M. S., Barata, L., Ferreira, A. E. N., Romão, S., et al. (2008). Catalysis and structural properties of Leishmania infantum glyoxalase II: Trypanothione specificity and phylogeny. Biochemistry, 47(1), 195 - 204.

Costa, E., Rocha, S., Rocha-Pereira, P., Castro, E., et al. (2008). Changes in red blood cells membrane protein composition during hemodialysis procedure. Renal Failure, 30(10), 971 - 975.

Dutra, I., Santos, M. R., Soares, M., Couto, A. R., et al. (2008). Characterisation of human papillomavirus (HPV) genotypes in the Azorean population, Terceira island. Infectious Agents and Cancer, 3(1).

Mota, A., Silva, P., Neves, D., Lemos, C., et al. (2008). Characterization of rat heart alkaline phosphatase isoenzymes and modulation of activity. Brazilian Journal of Medical and Biological Research, 41(7), 600 - 609.

Martins, S., Coutinho, P., Silveira, I., Giunti, P., et al. (2008). Cis-acting factors promoting the CAG intergenerational instability in Machado-Joseph disease. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 147(4), 439 - 446.

Melo, P., Pinazo-Durán, M. D., Salgado-Borges, J., & Tavares, M. A. (2008). Correlation of axon size and myelin occupancy in rats prenatally exposed to methamphetamine. Brain Research, 1222, 61 - 68.

Costa, E., Rocha, S., Rocha-Pereira, P., Castro, E., et al. (2008). Cross-talk between inflammation, coagulation/fibrinolysis and vascular access in hemodialysis patients. Journal of Vascular Access, 9(4), 248 - 253.

Sá-Moura, B., Albuquerque, L., Empadinhas, N., Da Costa, M. S., et al. (2008). Crystallization and preliminary crystallographic analysis of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 64(8), 760 - 763.

Libani, I. V., Guy, E. C., Melchiori, L., Schiro, R., et al. (2008). Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in ?-thalassemia. Blood, 112(3), 875 - 885.

Costa, E., Rocha, S., Rocha-Pereira, P., Reis, F., et al. (2008). DMT1 (NRAMP2/DCT1) Genetic Variability and Resistance to Recombinant Human Erythropoietin Therapy in Chronic Kidney Disease Patients under Haemodialysis. Acta Haematologica, 120(1), 11 - 13.

Coelho, P. A., Queiroz-Machado, J., Carmo, A. M., Moutinho-Pereira, S., et al. (2008). Dual role of topoisomerase II in centromere resolution and aurora B activity. PLoS Biology, 6(8), 1758 - 1777.

Coelho, P. A., Queiroz-Machado, J., Carmo, A. M., Moutinho-Pereira, S., et al. (2008). Dual role of topoisomerase II in centromere resolution and aurora B activity. PLoS biology, 6(8).

Marques, A. P. G. C., Oliveira, R. S., Samardjieva, K. A., Pissarra, J., et al. (2008). EDDS and EDTA-enhanced zinc accumulation by solanum nigrum inoculated with arbuscular mycorrhizal fungi grown in contaminated soil. Chemosphere, 70(6), 1002 - 1014.

Vaz-Da-Silva, M., Loureiro, A. I., Falcao, A., Nunes, T., et al. (2008). Effect of food on the pharmacokinetic profile of trans-resveratrol. International Journal of Clinical Pharmacology and Therapeutics, 46(11), 564 - 570.

Almeida, L., Falcão, A., Vaz-Da-Silva, M., Nunes, T., et al. (2008). Effect of nebicapone on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. European Journal of Clinical Pharmacology, 64(10), 961 - 966.

Sousa, C., Nunes, C., Lúcio, M., Ferreira, H., et al. (2008). Effect of nonsteroidal anti-inflammatory drugs on the cellular membrane fluidity. Journal of Pharmaceutical Sciences, 97(8), 3195 - 3206.

Fernandes, J. C., Eaton, P., Nascimento, H., Belo, L., et al. (2008). Effects of chitooligosaccharides on human red blood cell morphology and membrane protein structure. Biomacromolecules, 9(12), 3346 - 3352.

Valentim, A. M., Alves, H. C., Silva, A. M., Olsson, I. A. S., & Antunes, L. M. (2008). Effects of depth of isoflurane anaesthesia on a cognition task in mice. British Journal of Anaesthesia, 101(3), 434 - 435.

Silva, F., Nogueira, L. C., Gonçalves, C., Ferreira, A. A., et al. (2008). Electrophoretic and HPLC methods for comparative study of the protein fractions of malts, worts and beers produced from Scarlett and Prestige barley (Hordeum vulgare L.) varieties. Food Chemistry, 106(2), 820 - 829.

Salomé Gomes, M., Fernandes, S. S., Cordeiro, J. V., Gomes, S. S., et al. (2008). Engagement of Toll-like receptor 2 in mouse macrophages infected with Mycobacterium avium induces non-oxidative and TNF-independent anti-mycobacterial activity. European Journal of Immunology, 38(8), 2180 - 2189.

Seixas, D., & Ayres Basto, M. (2008). Ethics in fMRI studies: A review of the EMBASE and MEDLINE literature. Clinical Neuroradiology, 18(2), 79 - 87.

Javaher, P., Kääriäinen, H., Kristoffersson, U., Nippert, I., et al. (2008). EuroGentest: DNA-based testing for heritable disorders in Europe. Community Genetics, 11(2), 75 - 120.

Martins, P., Schmitt, F., Almeida, H., & Frazão, J. M. (2008). Evaluation of parathyroid gland angiogenesis in chronic kidney disease associated with secondary hyperparathyroidism. Nephrology Dialysis Transplantation, 23(9), 2889 - 2894.

Bettencourt, B. F., Santos, M. R., Fialho, R. N., Couto, A. R., et al. (2008). Evaluation of two methods for computational HLA haplotypes inference using a real dataset. BMC Bioinformatics, 9.

Seneca, S., Morris, M. A., Patton, S., Elles, R., & Sequeiros, J. (2008). Experience and outcome of 3 years of a European EQA scheme for genetic testing of the spinocerebellar ataxias. European Journal of Human Genetics, 16(8), 913 - 920.

Magalhães, A., Melo, P., Alves, C. J., Tavares, M. A., et al. (2008). Exploratory behavior in rats postnatally exposed to cocaine and housed in an enriched environment. Annals of the New York Academy of Sciences (Vol. 1139, pp. 358 - 365).

Cardoso, I., Brito, M., & Saraiva, M. J. (2008). Extracellular matrix markers for disease progression and follow-up of therapies in familial amyloid polyneuropathy V30M TTR-related. Disease Markers, 25(1), 37 - 47.

Catarino, C., Rebelo, I., Belo, L., Rocha-Pereira, P., et al. (2008). Fetal lipoprotein changes in pre-eclampsia. Acta Obstetricia et Gynecologica Scandinavica, 87(6), 628 - 634.

Portaels, F., Meyers, W. M., Ablordey, A., Castro, A. G., et al. (2008). First cultivation and characterization of Mycobacterium ulcerans from the environment. PLoS Neglected Tropical Diseases, 2(3).

dos Santos, N. M. S., do Vale, A., Reis, M. I. R., & Silva, M. T. (2008). Fish and apoptosis: Molecules and pathways. Current Pharmaceutical Design, 14(2), 148 - 169.

Silva, M. T., do Vale, A., & dos Santos, N. M. S. (2008). Fish and apoptosis: Studies in disease and pharmaceutical design. Current Pharmaceutical Design, 14(2), 170 - 183.

de Araujo, I. E., Oliveira-Maia, A. J., Sotnikova, T. D., Gainetdinov, R. R., et al. (2008). Food Reward in the Absence of Taste Receptor Signaling. Neuron, 57(6), 930 - 941.

Almeida, L., Kashdan, T. B., Coelho, R., Albino-Teixeira, A., & Soares-Da-Silva, P. (2008). Healthy subjects volunteering for phase I studies: Influence of curiosity, exploratory tendencies and perceived self-efficacy. International Journal of Clinical Pharmacology and Therapeutics, 46(3), 109 - 118.

Ouaïssi, M., Sielezneff, I., Silvestre, R., Sastre, B., et al. (2008). High histone deacetylase 7 (HDAC7) expression is significantly associated with adenocarcinomas of the pancreas. Annals of Surgical Oncology, 15(8), 2318 - 2328.

Ouaïssi, M., Cabral, S., Tavares, J., Cordeiro Da Silva, A., et al. (2008). Histone deacetylase (HDAC) encoding gene expression in pancreatic cancer cell lines and cell sensitivity to HDAC inhibitors. Cancer Biology and Therapy, 7(4), 523 - 531.

Spínola, C., Bruges-Armas, J., Brehm, A., & Spínola, H. (2008). HLA-A polymorphisms in four ethnic groups from Guinea-Bissau (West Africa) inferred from sequence-based typing. Tissue Antigens, 72(6), 593 - 598.

Alves, C. J., Magalhães, A., Summavielle, T., Melo, P., et al. (2008). Hormonal, neurochemical, and behavioral response to a forced swim test in adolescent rats throughout cocaine withdrawal. Annals of the New York Academy of Sciences (Vol. 1139, pp. 366 - 373).

Santos, C., Wanderley, H., Vedolin, L., Pena, S. D. J., et al. (2008). Huntington disease-like 2: The first patient with apparent European ancestry. Clinical Genetics, 73(5), 480 - 485.

Pinto, D., Duarte, M., Soares, S., Tropschug, M., & Videira, A. (2008). Identification of all FK506-binding proteins from Neurospora crassa. Fungal Genetics and Biology, 45(12), 1600 - 1607.

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Borges, O., Cordeiro-da-Silva, A., Tavares, J., Santarém, N., et al. (2008). Immune response by nasal delivery of hepatitis B surface antigen and codelivery of a CpG ODN in alginate coated chitosan nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics, 69(2), 405 - 416.

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Silva, J., Silva, C., Saraiva, L., Silva, A., et al. (2008). Intraprostatic Botulinum Toxin Type A Injection in Patients Unfit for Surgery Presenting with Refractory Urinary Retention and Benign Prostatic Enlargement. Effect on Prostate Volume and Micturition Resumption. European Urology, 53(1), 153 - 159.

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Almeida, T., Marques, M., Mojzita, D., Amorim, M. A., et al. (2008). Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and apoptosis. Molecular Biology of the Cell, 19(3), 865 - 876.

Macedo-Ribeiro, S., Almeida, C., Calisto, B. M., Friedrich, T., et al. (2008). Isolation, cloning and structural characterisation of boophilin, a multifunctional Kunitz-type proteinase inhibitor from the cattle tick. PLoS ONE, 3(2).

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Tavares, J., Ouaissi, A., Santarém, N., Sereno, D., et al. (2008). The Leishmania infantum cytosolic SIR2-related protein 1 (LiSIR2RP1) is an NAD+-dependent deacetylase and ADP-ribosyltransferase. Biochemical Journal, 415(3), 377 - 386.

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Alonso, I., Marques, J. M., Sousa, N., Sequeiros, J., et al. (2008). Motor and cognitive deficits in the heterozygous leaner mouse, a Cav2.1 voltage-gated Ca2+ channel mutant. Neurobiology of Aging, 29(11), 1733 - 1743.

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Pereira, P. J. B., Empadinhas, N., Albuquerque, L., Sá-Moura, B., et al. (2008). Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: Structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis. PLoS ONE, 3(11).

Amaral, M., Dias, A. G., Gomes, P. S., Lopes, M. A., et al. (2008). Nanocrystalline diamond: In vitro biocompatibility assessment by MG63 and human bone marrow cells cultures. Journal of Biomedical Materials Research - Part A, 87(1), 91 - 99.

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Cepa, M., Correia-da-Silva, G., da Silva, E., Roleira, F. M. F., et al. (2008). New steroidal aromatase inhibitors: Suppression of estrogen-dependent breast cancer cell proliferation and induction of cell death. BMC Cell Biology, 9.

Rajasekariah, G. - H. R., Cardoso, L., Dogcio, D. A., Martin, S. K., & Smithyman, A. M. (2008). A novel exo-antigen-based ELISA for the detection of canine leishmaniasis. American Journal of Tropical Medicine and Hygiene, 78(4), 616 - 623.

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Sousa, S. R., Lamghari, M., Sampaio, P., Moradas-Ferreira, P., & Barbosa, M. A. (2008). Osteoblast adhesion and morphology on TiO2 depends on the competitive preadsorption of albumin and fibronectin. Journal of Biomedical Materials Research - Part A, 84(2), 281 - 290.

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Pinto, M., Sousa, M., Lima, D., & Tavares, I. (2008). Participation of ?-opioid, GABAB, and NK1 receptors of major pain control medullary areas in pathways targeting the rat spinal cord: Implications for descending modulation of nociceptive transmission. Journal of Comparative Neurology, 510(2), 175 - 187.

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Almeida, L., Falcão, A., Vaz-Da-Silva, M., Coelho, R., et al. (2008). Personality characteristics of volunteers in phase 1 studies and likelihood of reporting adverse events. International Journal of Clinical Pharmacology and Therapeutics, 46(7), 340 - 348.

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Sims, A. - M., Timms, A. E., Bruges-Armas, J., Burgos-Vargas, R., et al. (2008). Prospective meta-analysis of interleukin 1 gene complex polymorphisms confirms associations with ankylosing spondylitis. Annals of the Rheumatic Diseases, 67(9), 1305 - 1309.

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Castro, M. - J., Nunes, B., De Vries, B., Lemos, C., et al. (2008). Two novel functional mutations in the Na+, K+ -ATPase ?2-subunit ATP1A2 gene in patients with familial hemiplegic migraine and associated neurological phenotypes. Clinical Genetics, 73(1), 37 - 43.

Sousa, S., Ajzenberg, D., Vilanova, M., Costa, J., & Dardé, M. - L. (2008). Use of GRA6-derived synthetic polymorphic peptides in an immunoenzymatic assay to serotype Toxoplasma gondii in human serum samples collected from three continents. Clinical and Vaccine Immunology, 15(9), 1380 - 1386.

Garrido, E. M. P. J., Garrido, J. M. P. J., Esteves, M., Santos-Silva, A., et al. (2008). Voltammetric and DFT studies on viloxazine: Analytical application to pharmaceuticals and biological fluids. Electroanalysis, 20(13), 1454 - 1462.

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Cardoso, L., Schallig, H. D. F. H., Cordeiro-da-Silva, A., Cabral, M., et al. (2007). Anti-Leishmania humoral and cellular immune responses in naturally infected symptomatic and asymptomatic dogs. Veterinary Immunology and Immunopathology, 117(1-2), 35 - 41.

Liz, M. A., Gomes, C. M., Saraiva, M. J., & Sousa, M. M. (2007). ApoA-I cleaved by transthyretin has reduced ability to promote cholesterol efflux and increased amyloidogenicity. Journal of Lipid Research, 48(11), 2385 - 2395.

Silva, M. T., Portaels, F., & Pedrosa, J. (2007). Aquatic insects and Mycobacterium ulcerans: An association relevant to buruli ulcer control?. PLoS Medicine, 4(2), 0229 - 0231.

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Amaral, I. F., Cordeiro, A. L., Sampaio, P., & Barbosa, M. A. (2007). Attachment, spreading and short-term proliferation of human osteoblastic cells cultured on chitosan films with different degrees of acetylation. Journal of Biomaterials Science, Polymer Edition, 18(4), 469 - 485.

Almeida, B., Sampaio-Marques, B., Carvalho, J., Silva, M. T., et al. (2007). An atypical active cell death process underlies the fungicidal activity of ciclopirox olamine against the yeast Saccharomyces cerevisiae. FEMS Yeast Research, 7(3), 404 - 412.

Macedo, B., Batista, A. R., Do Amaral, J. B., & Saraiva, M. J. (2007). Biomarkers in the assessment of therapies for familial amyloidotic polyneuropathy. Molecular Medicine, 13(11-12), 584 - 591.

Silva, C., Silva, J., Castro, H., Reis, F., et al. (2007). Bladder sensory desensitization decreases urinary urgency. BMC Urology, 7.

Sabugosa-Madeira, B., Abreu, I., Ribeiro, H., & Cunha, M. (2007). Bt transgenic maize pollen and the silent poisoning of the hive. Journal of Apicultural Research, 46(1), 57 - 58.

Maia, A. F., Lopes, C. S., & Sunkel, C. E. (2007). BubR1 and CENP-E have antagonistic effects upon the stability of microtubule-kinetochore attachments in Drosophila S2 cell mitosis. Cell Cycle, 6(11), 1367 - 1378.

Mendes, M. V., Recio, E., Antón, N., Guerra, S. M., et al. (2007). Cholesterol Oxidases Act as Signaling Proteins for the Biosynthesis of the Polyene Macrolide Pimaricin. Chemistry and Biology, 14(3), 279 - 290.

Marques, F., Sousa, J. C., Correia-Neves, M., Oliveira, P., et al. (2007). The choroid plexus response to peripheral inflammatory stimulus. Neuroscience, 144(2), 424 - 430.

Nascimento, D. S., Vale, A. D., Tomás, A. M., Zou, J., et al. (2007). Cloning, promoter analysis and expression in response to bacterial exposure of sea bass (Dicentrarchus labrax L.) interleukin-12 p40 and p35 subunits. Molecular Immunology, 44(9), 2277 - 2291.

Sanchez-Burgos, G., Mezquita-Vega, R. G., Escobedo-Ortegon, J., Ramirez-Sierra, M. J., et al. (2007). Comparative evaluation of therapeutic DNA vaccines against Trypanosoma cruzi in mice. FEMS Immunology and Medical Microbiology, 50(3), 333 - 341.

Cardoso, I., Almeida, M. R., Ferreira, N., Arsequell, G., et al. (2007). Comparative in vitro and ex vivo activities of selected inhibitors of transthyretin aggregation: Relevance in drug design. Biochemical Journal, 408(1), 131 - 138.

Oliveira, R. A., Heidmann, S., & Sunkel, C. E. (2007). Condensin I binds chromatin early in prophase and displays a highly dynamic association with Drosophila mitotic chromosomes. Chromosoma, 116(3), 259 - 274.

Boneca, I. G., Dussurget, O., Cabanes, D., Nahori, M. - A., et al. (2007). A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system. Proceedings of the National Academy of Sciences of the United States of America, 104(3), 997 - 1002.

Hansen, D., Macedo-Ribeiro, S., Veríssimo, P., Yoo Im, S., et al. (2007). Crystal structure of a novel cysteinless plant Kunitz-type protease inhibitor. Biochemical and Biophysical Research Communications, 360(4), 735 - 740.

do Vale, A., Costa-Ramos, C., Silva, D. S. P., Macedo, P. M., et al. (2007). Cytochemical and ultrastructural study of anoikis and secondary necrosis in enterocytes detached in vivo. Apoptosis, 12(6), 1069 - 1083.

Gobec, S., Plantan, I., Mravljak, J., ?vajger, U., et al. (2007). Design, synthesis, biochemical evaluation and antimycobacterial action of phosphonate inhibitors of antigen 85C, a crucial enzyme involved in biosynthesis of the mycobacterial cell wall. European Journal of Medicinal Chemistry, 42(1), 54 - 63.

Vieira, J., Morales-Hojas, R., Santos, R. A. M., & Vieira, C. P. (2007). Different positively selected sites at the gametophytic self-incompatibility pistil S-RNase gene in the Solanaceae and Rosaceae (Prunus, Pyrus, and Malus). Journal of Molecular Evolution, 65(2), 175 - 185.

Castanheiro, R. A. P., Pinto, M. M. M., Silva, A. M. S., Cravo, S. M. M., et al. (2007). Dihydroxyxanthones prenylated derivatives: Synthesis, structure elucidation, and growth inhibitory activity on human tumor cell lines with improvement of selectivity for MCF-7. Bioorganic and Medicinal Chemistry, 15(18), 6080 - 6088.

Spínola, H., Bruges-Armas, J., & Brehm, A. (2007). Discrepancies in HLA typing by PCR-SSOP and SBT techniques: A case study. Human Biology, 79(5), 537 - 543.

Malmanche, N., Owen, S., Gegick, S., Steffensen, S., et al. (2007). Drosophila BubR1 Is Essential for Meiotic Sister-Chromatid Cohesion and Maintenance of Synaptonemal Complex. Current Biology, 17(17), 1489 - 1497.

Sousa, A., Reis, R., Sampaio, P., & Sunkel, C. E. (2007). The Drosophila CLASP homologue, mast/orbit regulates the dynamic behaviour of interphase microtubules by promoting the pause state. Cell Motility and the Cytoskeleton, 64(8), 605 - 620.

Reis, F., Teixeira de Lemos, E., Almeida, L., Parada, B., et al. (2007). Dual Effect of Nitrate Therapy for Cyclosporine-Induced Hypertension on Vascular and Platelet Morphofunctional Markers; An Animal Model. Transplantation Proceedings, 39(8), 2501 - 2506.

Sousa, S. R., Manuela Brás, M., Moradas-Ferreira, P., & Barbosa, M. A. (2007). Dynamics of fibronectin adsorption on TiO 2 surfaces. Langmuir, 23(13), 7046 - 7054.

Ascensão, A., Ferreira, R., Marques, F., Oliveira, E., et al. (2007). Effect of off-road competitive motocross race on plasma oxidative stress and damage markers. British Journal of Sports Medicine, 41(2), 101 - 105.

Gomes, J. R. B., Sousa, E. A., Gonçalves, J. M., Gales, L., et al. (2007). Energetic and structural characterization of 2-R-3-methylquinoxaline-1,4- dioxides (R = benzoyl or tert-butoxycarbonyl): Experimental and computational studies. Journal of Physical Organic Chemistry, 20(7), 491 - 498.

Antoniou, A. N., Santos, S. G., Campbell, E. C., Lynch, S., et al. (2007). ERp57 interacts with conserved cysteine residues in the MHC class I peptide-binding groove. FEBS Letters, 581(10), 1988 - 1992.

Benninger, Y., Thurnherr, T., Pereira, J. A., Krause, S., et al. (2007). Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development. Journal of Cell Biology, 177(6), 1051 - 1061.

Olsson, I. A. S., Hansen, A. K., & Sandøe, P. (2007). Ethics and refinement in animal research [4]. Science, 317(5845), 1680.

Borges, O., Tavares, J., de Sousa, A., Borchard, G., et al. (2007). Evaluation of the immune response following a short oral vaccination schedule with hepatitis B antigen encapsulated into alginate-coated chitosan nanoparticles. European Journal of Pharmaceutical Sciences, 32(4-5), 278 - 290.

Torrado, E., Fraga, A. G., Castro, A. G., Stragier, P., et al. (2007). Evidence for an intramacrophage growth phase of Mycobacterium ulcerans. Infection and Immunity, 75(2), 977 - 987.

Santos, S. F. A., Rebelo, S., Derkach, V. A., & Safronov, B. V. (2007). Excitatory interneurons dominate sensory processing in the spinal substantia gelatinosa of rat. Journal of Physiology, 581(1), 241 - 254.

De Lemos, E. T., Reis, F., Baptista, S., Pinto, R., et al. (2007). Exercise training is associated with improved levels of C-reactive protein and adiponectin in ZDF (type 2) diabetic rats. Medical Science Monitor, 13(8), BR168 - BR174.

Munar-Qués, M., Masjuan, J., Coelho, T., Moreira, P., et al. (2007). Familial amyloid polyneuropathy associated with TTRSer50Arg mutation in two Iberian families presenting a novel single base change in the mutant gene. Amyloid, 14(2), 147 - 152.

Reis, M. I. R., do Vale, A., Pinto, C., Nascimento, D. S., et al. (2007). First molecular cloning and characterisation of caspase-9 gene in fish and its involvement in a gram negative septicaemia. Molecular Immunology, 44(7), 1765 - 1775.

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Dinis, P., Silva, J., Ribeiro, M. J., Avelino, A., et al. (2004). Bladder C-fiber desensitization induces a long-lasting improvement of BPH-associated storage LUTS: A pilot study. European Urology, 46(1), 88 - 94.

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Miranda, C. J., Makui, H., Andrews, N. C., & Santos, M. M. (2004). Contributions of ?2-microglobulin-dependent molecules and lymphocytes to iron regulation: Insights from HfeRag1-/- and ?2mRag1 -/- double knock-out mice. Blood, 103(7), 2847 - 2849.

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Oikemus, S. R., McGinnis, N., Queiroz-Machado, J., Tukachinsky, H., et al. (2004). Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect. Genes and Development, 18(15), 1850 - 1861.

Maiato, H., DeLuca, J., Salmon, E. D., & Earnshaw, W. C. (2004). The dynamic kinetochore-microtubule interface. Journal of Cell Science, 117(23), 5461 - 5477.

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Magalhães, A., Summavielle, T., Tavares, M. A., & de Sousa, L. (2004). Effects of postnatal cocaine exposure and environmental enrichment on rat behavior in a forced swim test. Annals of the New York Academy of Sciences (Vol. 1025, pp. 619 - 629).

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Castelo-Branco, P., Furger, A., Wollerton, M., Smith, C., et al. (2004). Erratum: Polypyrimidine tract binding protein modulates efficiency of polyadenylation (Molecular and Cellular Biology (2004) 24, 10 (4174-4183)). Molecular and Cellular Biology, 24(15), 6889.

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Miranda, C. J., Santos, M. M., Ohshima, K., Tessaro, M., et al. (2004). Frataxin overexpressing mice. FEBS Letters, 572(1-3), 281 - 288.

do Carmo Costa, M., Gomes-da-Silva, J., Miranda, C. J., Sequeiros, J., et al. (2004). Genomic structure, promoter activity, and developmental expression of the mouse homologue of the Machado-Joseph disease (MJD) gene. Genomics, 84(2), 361 - 373.

Santos, M., do Carmo Costa, M., Edite Rio, M., José Sá, M., et al. (2004). Genotypes at the APOE and SCA2 loci do not predict the course of multiple sclerosis in patients of Portuguese origin. Multiple Sclerosis, 10(2), 153 - 157.

Soares, M. L., Coelho, T., Sousa, A., Holmgren, G., et al. (2004). Haplotypes and DNA sequence variation within and surrounding the transthyretin gene: Genotype-phenotype correlations in familial amyloid polyneuropathy (V30M) in Portugal and Sweden. European Journal of Human Genetics, 12(3), 225 - 237.

Sherwin, C. M., & Olsson, I. A. S. (2004). Housing conditions affect self-administration of anxiolytic by laboratory mice. Animal Welfare, 13(1), 33 - 38.

Sousa, S. R., Moradas-Ferreira, P., Saramago, B., Viseu Melo, L., & Barbosa, M. A. (2004). Human serum albumin adsorption on TiO2 from single protein solutions and from plasma. Langmuir, 20(22), 9745 - 9754.

Osório, H., Moradas-Ferreira, P., Günther Sillero, M. A., & Sillero, A. (2004). In Saccharomyces cerevisiae, the effect of H2O2 on ATP, but not on glyceraldehyde-3-phosphate dehydrogenase, depends on the glucose concentration. Archives of Microbiology, 181(3), 231 - 236.

Rocha-Pereira, P., Santos-Silva, A., Rebelo, I., Figueiredo, A., et al. (2004). The inflammatory response in mild and in severe psoriasis. British Journal of Dermatology, 150(5), 917 - 928.

Melnick, I. V., Santos, S. F. A., Szokol, K., Szûcs, P., & Safronov, B. V. (2004). Ionic Basis of Tonic Firing in Spinal Substantia Gelatinosa Neurons of Rat. Journal of Neurophysiology, 91(2), 646 - 655.

Beirão, I., Lobato, L., Costa, P. M., Fonseca, I., et al. (2004). Kidney and anemia in familial amyloidosis type I. Kidney international, 66(5), 2004 - 2009.

Maiato, H., & Sunkel, C. E. (2004). Kinetochore-microtubule interactions during cell division. Chromosome Research, 12(6), 585 - 597.

Vieira, L. M. M., Kijjoa, A., Silva, A. M. S., Mondranondra, I. - O., et al. (2004). Lanostanes and friedolanostanes from the bark of Garcinia speciosa. Phytochemistry, 65(4), 393 - 398.

Belo, L., Caslake, M., Santos-Silva, A., Castro, E. M. B., et al. (2004). LDL size, total antioxidant status and oxidised LDL in normal human pregnancy: A longitudinal study. Atherosclerosis, 177(2), 391 - 399.

Melnick, I. V., Santos, S. F. A., & Safronov, B. V. (2004). Mechanism of spike frequency adaptation in substantia gelatinosa neurones of rat. Journal of Physiology, 559(2), 383 - 395.

Sarmento, A., Guilhermino, L., & Afonso, A. (2004). Mercury chloride effects on the function and cellular integrity of sea bass (Dicentrarchus labrax) head kidney macrophages. Fish and Shellfish Immunology, 17(5), 489 - 498.

Rodrigues, L. G., Tavares, M. A., Wood, J. P. M., Schmidt, K. - G., & Osborne, N. N. (2004). Methamphetamine exacerbates the toxic effect of kainic acid in the adult rat retina. Neurochemistry International, 45(8), 1133 - 1141.

Maiato, H., Sampaio, P., & Sunkel, C. E. (2004). Microtubule-associated proteins and their essential roles during mitosis. International Review of Cytology (Vol. 241, pp. 53 - 153).

Santos, S. G., Powis, S. J., & Arosa, F. A. (2004). Misfolding of major histocompatibility complex class I molecules in activated T cells allows cis-interactions with receptors and signaling molecules and is associated with tyrosine phosphorylation. Journal of Biological Chemistry, 279(51), 53062 - 53070.

Sarmento, A., Marques, F., Ellis, A. E., & Afonso, A. (2004). Modulation of the activity of sea bass (Dicentrarchus labrax) head-kidney macrophages by macrophage activating factor(s) and lipopolysaccharide. Fish and Shellfish Immunology, 16(2), 79 - 92.

Guimarães, C. P., Domingues, P., Aubourg, P., Fouquet, F., et al. (2004). Mouse liver PMP70 and ALDP: Homomeric interactions prevail in vivo. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1689(3), 235 - 243.

De Carvalho, M., Linke, R. P., Domingos, F., Evangelista, T., et al. (2004). Mutant fibrinogen A-?-chain associated with hereditary renal amyloidosis and peripheral neuropathy. Amyloid, 11(3), 200 - 207.

Costa-Rodrigues, J., Carvalho, A. F., Gouveia, A. M., Fransen, M., et al. (2004). The N terminus of the peroxisomal cycling receptor, Pex5p, is required for redirecting the peroxisome-associated peroxin back to the cytosol. Journal of Biological Chemistry, 279(45), 46573 - 46579.

Alonso, I., Barros, J., Tuna, A., Seixas, A., et al. (2004). A novel R1347Q mutation in the predicted voltage sensor segment of the P/Q-type calcium-channel ?1A-subunit in a family with progressive cerebellar ataxia and hemiplegic migraine [6]. Clinical Genetics, 65(1), 70 - 72.

Ruano, D., Macedo, A., Dourado, A., Soares, M. J., et al. (2004). NR4A2 and schizophrenia: Lack of association in a Portuguese/Brazilian study. American Journal of Medical Genetics - Neuropsychiatric Genetics, 128 B(1), 41 - 45.

Magalhães, J., Ascensão, A., Viscor, G., Soares, J., et al. (2004). Oxidative Stress in Humans during and after 4 Hours of Hypoxia at a Simulated Altitude of 5500 m. Aviation Space and Environmental Medicine, 75(1), 16 - 22.

Sottomayor, M., Lopes Cardoso, I., Pereira, L. G., & Ros Barceló, A. (2004). Peroxidase and the biosynthesis of terpenoid indole alkaloids in the medicinal plant Catharanthus roseus (L.) G. Don. Phytochemistry Reviews, 3(1-2), 159 - 171.

Castelo-Branco, P., Furger, A., Wollerton, M., Smith, C., et al. (2004). Polypyrimidine tract binding protein modulates efficiency of polyadenylation. Molecular and Cellular Biology, 24(10), 4174 - 4183.

Pinto, R., Caseiro, C., Lemos, M., Lopes, L., et al. (2004). Prevalence of lysosomal storage diseases in Portugal. European Journal of Human Genetics, 12(2), 87 - 92.

Azevedo, J. E., Costa-Rodrigues, J., Guimarães, C. P., Oliveira, M. E., & Sá-Miranda, C. (2004). Protein translocation across the peroxisomal membrane. Cell Biochemistry and Biophysics, 41(3), 451 - 468.

Fleming, M., Lêdo, S., Rocha, J. C., & Sequeiros, J. (2004). Pshycho-social impact of presymptomatic testing in Machado-Joseph disease. Impacto psicológico do teste pré-sintomático na doença de Machado-Joseph. Resultados preliminaresArquivos de Medicina, 18(1-2), 72 - 75+92.

Silva, E., Castro, A., Lopes, A., Rodrigues, A., et al. (2004). A recombinant antigen recognized by Fasciola hepatica-infected hosts. Journal of Parasitology, 90(4), 746 - 751.

Santos, C., Pereira, A., Pereira, S., & Teixeira, J. (2004). Regulation of glutamine synthetase expression in sunflower cells exposed to salt and osmotic stress. Scientia Horticulturae, 103(1), 101 - 111.

Pestana, M., Santos, J., Santos, A., Coroas, A., et al. (2004). Renal dopamine and salt sensitivity of blood pressure in IgA nephropathy. Kidney and Blood Pressure Research, 27(2), 78 - 87.

Almeida, M. R., Macedo, B., Cardoso, I., Alves, I., et al. (2004). Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative. Biochemical Journal, 381(2), 351 - 356.

Santos, S. F. A., Melnick, I. V., & Safronov, B. V. (2004). Selective postsynaptic inhibition of tonic-firing neurons in substantia gelatinosa by ?-opioid agonist. Anesthesiology, 101(5), 1177 - 1183.

Moreira, M. - C., Klur, S., Watanabe, M., Németh, A. H., et al. (2004). Senataxin, the ortholog of a yeast RNA helicase, is mutant in ataxia-ocular apraxia 2. Nature Genetics, 36(3), 225 - 227.

Cardoso, E. M., Duarte, M. A., Ribeiro, E., Rodrigues, P., et al. (2004). A study of some hepatic immunological markers, iron load and virus genotype in chronic hepatitis C. Journal of Hepatology, 41(2), 319 - 326.

Altland, K., Winter, P., Saraiva, M. J. M., & Suhr, O. (2004). Sulfite and base for the treatment of familial amyloidotic polyneuropathy: Two additive approaches to stabilize the conformation of human amyloidogenic transthyretin. Neurogenetics, 5(1), 61 - 67.

Dinis, M., Tavares, D., Fonseca, A. J. M. M., Faria, R., et al. (2004). Therapeutic vaccine against Streptococcus sobrinus-induced caries. Journal of Dental Research, 83(4), 354 - 358.

Liz, M. A., Faro, C. J., Saraiva, M. J., & Sousa, M. M. (2004). Transthyretin, a new cryptic protease. Journal of Biological Chemistry, 279(20), 21431 - 21438.

Carlos Sousa, J., Grandela, C., Fernández-Ruiz, J., De Miguel, R., et al. (2004). Transthyretin is involved in depression-like behaviour and exploratory activity. Journal of Neurochemistry, 88(5), 1052 - 1058.

Castro, H., Sousa, C., Novais, M., Santos, M., et al. (2004). Two linked genes of Leishmania infantum encode tryparedoxins localised to cytosol and mitochondrion. Molecular and Biochemical Parasitology, 136(2), 137 - 147.

Sousa, T., Morato, M., Fernandes, E., Carvalho, F., & Albino-Teixeira, A. (2004). Xanthine oxidase inhibition by 1,3-dipropyl-8-sulfophenyl-xanthine (DPSPX), an antagonist of adenosine receptors. Journal of Enzyme Inhibition and Medicinal Chemistry, 19(1), 11 - 15.