Force spectroscopy reveals the presence of structurally modified dimers in transthyretin amyloid annular oligomers - Pires, R.H.; Saraiva, M.J.; Damas, A.M.; Kellermayer, M.S.Z. (Journal of Molecular Recognition, 2017)

On growth rate hysteresis and catastrophic crystal growth - Ferreira, C.; Rocha, F.A.; Damas, A.M.; Martins, P.M. (Journal of Crystal Growth, 2013)

Distinct Annular Oligomers Captured along the Assembly and Disassembly Pathways of Transthyretin Amyloid Protofibrils - Pires, R.H.; Karsai, Á.; Saraiva, M.J.; Damas, A.M.; Kellermayer, M.S.Z. (PLoS ONE, 2012)

A generic crystallization-like model that describes the kinetics of amyloid fibril formation - Crespo, R.; Rocha, F.A.; Damas, A.M.; Martins, P.M. (Journal of Biological Chemistry, 2012)

Transthyretin is a metallopeptidase with an inducible active site - Liz, M.A.; Leite, S. C.; Juliano, L.; Saraiva, M.J.; Damas, A.M.; Bur, D.; Sousa, M.M. (Biochemical Journal, 2012)

Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein - Noborna, F.; O'Callaghan, P.; Hermansson, E.; Zhang, X.; Ancsin, J.B.; Damas, A.M.; Dacklin, I.; Presto, J.; Johansson, J.; Saraiva, M.J.; Lundgren, E.; Kisilevsky, R.; et al. (Proceedings of the National Academy of Sciences of the United States of America, 2011)

Prenylated derivatives of baicalein and 3,7-dihydroxyflavone: Synthesis and study of their effects on tumor cell lines growth, cell cycle and apoptosis - Neves, M.P.; Cidade, H.; Pinto, M.; Silva, A.M.S.; Gales, L.; Damas, A.M.; Lima, R.T.; Vasconcelos, M.H.; Nascimento, M.D.S.J. (European Journal of Medicinal Chemistry, 2011)

Small temperature oscillations promote protein crystallization - Ferreira, C.; Crespo, R.; Martins, P.M.; Gales, L.; Rocha, F.; Damas, A.M. (CrystEngComm, 2011)

Solution structure of the soluble receptor for advanced glycation end products (sRAGE) - Sárkány, Z.; Ikonen, T.P.; Ferreira-Da-Silva, F.; Saraiva, M.J.; Svergun, D.; Damas, A.M. (Journal of Biological Chemistry, 2011)

Structural insights into a zinc-dependent pathway leading to Leu55Pro transthyretin amyloid fibrils - Castro-Rodrigues, A.F.; Gales, L.; Saraiva, M.J.; Damas, A.M. (Acta Crystallographica Section D: Biological Crystallography, 2011)

Structure and assembly-disassembly properties of wild-type transthyretin amyloid protofibrils observed with atomic force microscopy - Pires, R.H.; Saraiva, M.J.; Damas, A.M.; Kellermayer, M.S.Z. (Journal of Molecular Recognition, 2011)

Unsteady-state inhibition of crystal growth caused by solution impurities - Martins, P.M.; Rocha, F.; Damas, A.M.; Rein, P. (CrystEngComm, 2011)

Dipeptide crystals as excellent permselective materials: Sequential exclusion of argon, nitrogen, and oxygen - Afonso, R.V.; Durão, J.; Mendes, A.; Damas, A.M.; Gales, L. (Angewandte Chemie - International Edition, 2010)

Experimental and computational studies on the structural and thermodynamic properties of two sulfur heterocyclic keto compounds - Freitas, V.L.S.; Gomes, J.R.B.; Gales, L.; Damas, A.M.; Ribeiro Da Silva, M.D.M.C. (Journal of Chemical and Engineering Data, 2010)

FH8 - A small EF-hand protein from Fasciola hepatica - Fraga, H.; Faria, T.Q.; Pinto, F.; Almeida, A.; Brito, R.M.M.; Damas, A.M. (FEBS Journal, 2010)

Functional characterization of Arabidopsis thaliana transthyretin-like protein - Pessoa, J.; Sárkány, Z.; Ferreira-Da-Silva, F.; Martins, S.; Almeida, M.R.; Li, J.; Damas, A.M. (BMC Plant Biology, 2010)

Potential use of ultrasound to promote protein crystallization - Crespo, R.; Martins, P.M.; Gales, L.; Rocha, F.; Damas, A.M. (Journal of Applied Crystallography, 2010)

1-Hydr-oxy-3-(3-methyl-but-2-en-yloxy)xanthone - Gales, L.; Castanheiro, R.A.P.; Pinto, M.M.M.; Damas, A.M. (Acta Crystallographica Section E: Structure Reports Online, 2009)

Bromoalkoxyxanthones as promising antitumor agents: Synthesis, crystal structure and effect on human tumor cell lines - Sousa, E.; Paiva, A.; Nazareth, N.; Gales, L.; Damas, A.M.; Nascimento, M.S.J.; Pinto, M. (European Journal of Medicinal Chemistry, 2009)

Iodine atoms: a new molecular feature for the design of potent transthyretin fibrillogenesis inhibitors. - Mairal, T.; Nieto, J.; Pinto, M.; Almeida, M.R.; Gales, L.; Ballesteros, A.; Barluenga, J.; Pérez, J.J.; Vázquez, J.T.; Centeno, N.B.; Saraiva, M.J.; Damas, A.M.; et al. (PLoS ONE, 2009)

Iodine atoms: A new molecular feature for the design of potent transthyretin fibrillogenesis inhibitors - Mairal, T.; Nieto, J.; Pinto, M.; Almeida, M.R.; Gales, L.; Ballesteros, A.; Barluenga, J.; Pérez, J.J.; Vázquez, J.T.; Centeno, N.B.; Saraiva, M.J.; Damas, A.M.; et al. (PLoS ONE, 2009)

Unsteady-state transfer of impurities during crystal growth of sucrose in sugarcane solutions - Martins, P.M.; Ferreira, A.; Polanco, S.; Rocha, F.; Damas, A.M.; Rein, P. (Journal of Crystal Growth, 2009)

Iodination of salicylic acid improves its binding to transthyretin - Gales, L.; Almeida, M.R.; Arsequell, G.; Valencia, G.; Saraiva, M.J.; Damas, A.M. (Biochimica et Biophysica Acta - Proteins and Proteomics, 2008)

Rationalizing protein crystallization screenings through water equilibration theory and protein solubility data - Martins, P.M.; Pessoa, J.; Sàrkàny, Z.; Rocha, F.; Damas, A.M. (Crystal Growth and Design, 2008)

Understanding water equilibration fundamentals as a step for rational protein crystallization - Martins, P.M.; Rocha, F.; Damas, A.M. (PLoS ONE, 2008)

Dihydroxyxanthones prenylated derivatives: Synthesis, structure elucidation, and growth inhibitory activity on human tumor cell lines with improvement of selectivity for MCF-7 - Castanheiro, R.A.P.; Pinto, M.M.M.; Silva, A.M.S.; Cravo, S.M.M.; Gales, L.; Damas, A.M.; Nazareth, N.; Nascimento, M.S.J.; Eaton, G. (Bioorganic and Medicinal Chemistry, 2007)

Energetic and structural characterization of 2-R-3-methylquinoxaline-1,4- dioxides (R = benzoyl or tert-butoxycarbonyl): Experimental and computational studies - Gomes, J.R.B.; Sousa, E.A.; Gonçalves, J.M.; Gales, L.; Damas, A.M.; Gomes, P.; Pandey, S.; Acree Jr., W.E.; Da Silva, M.D.M.C.R. (Journal of Physical Organic Chemistry, 2007)

Merodrimanes and other constituents from Talaromyces thailandiasis - Dethoup, T.; Manoch, L.; Kijjoa, A.; Pinto, M.; Gales, L.; Damas, A.M.; Silva, A.M.S.; Eaton, G.; Herz, W. (Journal of Natural Products, 2007)

Structural basis for the protective role of sulfite against transthyretin amyloid formation - Gales, L.; Saraiva, M.J.; Damas, A.M. (Biochimica et Biophysica Acta - Proteins and Proteomics, 2007)

The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin - Morais-De-Sá, E.; Neto-Silva, R.M.; Pereira, P.J.B.; Saraiva, M.J.; Damas, A.M. (Acta Crystallographica Section D: Biological Crystallography, 2006)

The crystal and solution structures of glyceraldehyde-3-phosphate dehydrogenase reveal different quaternary structures - Ferreira-Da-Silva, F.; Pereira, P.J.B.; Gales, L.; Roessle, M.; Svergun, D.I.; Moradas-Ferreira, P.; Damas, A.M. (Journal of Biological Chemistry, 2006)

3,4-Dihydroxy-9H-xanthen-9-one trihydrate - Gales, L.; Sousa, M.E.; Pinto, M.M.M.; Damas, A.M. (Acta Crystallographica Section E: Structure Reports Online, 2005)

The binding of xanthone derivatives to transthyretin - Maia, F.; Almeida, M.D.R.; Gales, L.; Kijjoa, A.; Pinto, M.M.M.; Saraiva, M.J.; Damas, A.M. (Biochemical Pharmacology, 2005)

Human transthyretin in complex with iododiflunisal: Structural features associated with a potent amyloid inhibitor - Gales, L.; Macedo-Ribeiro, S.; Arsequell, G.; Valencia, G.; Saraiva, M.J.; Damas, A.M. (Biochemical Journal, 2005)

Small transthyretin (TTR) ligands as possible therapeutic agents in TTR amyloidoses - Almeida, M.R.; Gales, L.; Damas, A.M.; Cardoso, I.; Saraiva, M.J. (Current Drug Targets: CNS and Neurological Disorders, 2005)

Towards a structural understanding of the fibrillization pathway in Machado-Joseph's disease: Trapping early oligomers of non-expanded ataxin-3 - Gales, L.; Cortes, L.; Almeida, C.; Melo, C.V.; Costa, M.D.C.; MacIel, P.; Clarke, D.T.; Damas, A.M.; Macedo-Ribeiro, S. (Journal of Molecular Biology, 2005)

Xanthones - A structural perspective - Gales, L.; Damas, A.M. (Current Medicinal Chemistry, 2005)

X-ray crystallographic studies of two transthyretin variants: Further insights into amyloidogenesis - Neto-Silva, R.M.; Macedo-Ribeiro, S.; Pereira, P.J.B.; Coll, M.; Saraiva, M.J.; Damas, A.M. (Acta Crystallographica Section D: Biological Crystallography, 2005)

Bioactive friedolanostanes and 11(10→8)-abeolanostanes from the bark of Garcinia speciosa - Vieira, L.M.M.; Kijjoa, A.; Wilairat, R.; Nascimento, M.S.J.; Gales, L.; Damas, A.M.; Silva, A.M.S.; Mondranondra, I.-O.; Herz, W. (Journal of Natural Products, 2004)

The crystal structure of transthyretin in complex with diethylstilbestrol: A promising template for the design of amyloid inhibitors - Morais-De-Sá, E.; Pereira, P.J.B.; Saraiva, M.J.; Damas, A.M. (Journal of Biological Chemistry, 2004)

Lanostanes and friedolanostanes from the bark of Garcinia speciosa - Vieira, L.M.M.; Kijjoa, A.; Silva, A.M.S.; Mondranondra, I.-O.; Kengthong, S.; Gales, L.; Damas, A.M.; Herz, W. (Phytochemistry, 2004)