Exploring the power of yeast to model aging and age-related neurodegenerative disorders - Oliveira, A.V.; Vilaça, R.; Santos, C.N.; Costa, V.; Menezes, R. (Biogerontology, 2017)

The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes - Lemos, V.; de Oliveira, R.M.; Naia, L.; Szegö, E.; Ramos, E.; Pinho, S.; Magro, F.; Cavadas, C.; Cristina Rego, A.; Costa, V.; Outeiro, T.F.; Gomes, P. (Human Molecular Genetics, 2017)

Ceramide signaling targets the PP2A-like protein phosphatase Sit4p to impair vacuolar function, vesicular trafficking and autophagy in Isc1p deficient cells - Teixeira, V.; Medeiros, T.C.; Vilaça, R.; Ferreira, J.; Moradas-Ferreira, P.; Costa, V. (Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 2016)

The ceramide-activated protein phosphatase Sit4p controls lifespan, mitochondrial function and cell cycle progression by regulating hexokinase 2 phosphorylation - Barbosa, A.D.; Pereira, C.; Osorio, H.; Moradas-Ferreira, P.; Costa, V. (Cell Cycle, 2016)

Production of orotic acid by a Klura3δ mutant of Kluyveromyces lactis - Carvalho, N.; Coelho, E.; Gales, L.; Costa, V.; Teixeira, J.A.; Moradas-Ferreira, P. (Journal of Bioscience and Bioengineering, 2016)

Unraveling the role of the Target of Rapamycin signaling in sphingolipid metabolism - Teixeira, V.; Costa, V. (Progress in Lipid Research, 2016)

Ceramide signalling impinges on Sit4p and Hog1p to promote mitochondrial fission and mitophagy in Isc1p-deficient cells - Teixeira, V.; Medeiros, T.C.; Vilaça, R.; Pereira, A.T.; Chaves, S. R.; Côrte-Real, M.; Moradas-Ferreira, P.; Costa, V. (Cellular Signalling, 2015)

Effect of myricetin, pyrogallol, and phloroglucinol on yeast resistance to oxidative stress - Mendes, V.; Vilaça, R.; de Freitas, V.; Ferreira, P.M.; Mateus, N.; Costa, V. (Oxidative Medicine and Cellular Longevity, 2015)

LiZIP3 is a cellular zinc transporter that mediates the tightly regulated import of zinc in Leishmania infantum parasites - Carvalho, S.; Barreira da Silva, R.; Shawki, A.; Castro, H.; Lamy, M.; Eide, D.; Costa, V.; Mackenzie, B.; Tomás, A.M. (Molecular Microbiology, 2015)

A yeast model of the Parkinson's disease-associated protein Parkin - Pereira, C.; Costa, V.; Martins, L.M.; Saraiva, L. (Experimental Cell Research, 2015)

Effect of diflubenzuron on the development of Pinus pinaster seedlings inoculated with the ectomycorrhizal fungus Pisolithus tinctorius - Ramos, M. A.; Sousa, N. R.; Franco, A.R.; Costa, V.; Oliveira, R.S.; Castro, P.M.L. (Environmental Science and Pollution Research, 2013)

Using yeast to uncover the regulation of protein kinase Cδ by ceramide - Bessa, C.; Pereira, C.; Leão, M.; Maciel, C.; Gomes, S.; Gonçalves, J.; Corte-Real, M.; Costa, V.; Saraiva, L. (FEMS Yeast Research, 2013)

Activation of the Hog1p kinase in Isc1p-deficient yeast cells is associated with mitochondrial dysfunction, oxidative stress sensitivity and premature aging - Barbosa, A.D.; Graça, J.; Mendes, V.; Chaves, S. R.; Amorim, M.A.; Mendes, M.V.; Moradas-Ferreira, P.; Côrte-Real, M.; Costa, V. (Mechanisms of Ageing and Development, 2012)

Quercetin Protects Saccharomyces cerevisiae against Oxidative Stress by Inducing Trehalose Biosynthesis and the Cell Wall Integrity Pathway - Vilaça, R.; Mendes, V.; Mendes, M.V.; Carreto, L.; Amorim, M.A.; de Freitas, V.; Moradas-Ferreira, P.; Mateus, N.; Costa, V. (PLoS ONE, 2012)

Requirement of glutathione for Sod1 activation during lifespan extension - Mannarino, S.C.; Vilela, L.F.; Brasil, A.A.; Aranha, J.N.; Moradas-Ferreira, P.; Pereira, M.D.; Costa, V.; Eleutherio, E.C.A. (Yeast, 2011)

Role for Sit4p-dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p-deficient cells - Barbosa, A.D.; Osório, H.; Sims, K.J.; Almeida, T.; Alves, M.; Bielawski, J.; Amorim, M.A.; Moradas-Ferreira, P.; Hannun, Y.A.; Costa, V. (Molecular Microbiology, 2011)

Heme as a source of iron to Leishmania infantum amastigotes - Carvalho, S.; Cruz, T.; Santarém, N.; Castro, H.; Costa, V.; Tomás, A.M. (Acta Tropica, 2009)

Glutathione is necessary to ensure benefits of calorie restriction during ageing in Saccharomyces cerevisiae - Mannarino, S.C.; Amorim, M.A.; Pereira, M.D.; Moradas-Ferreira, P.; Panek, A.D.; Costa, V.; Eleutherio, E.C.A. (Mechanisms of Ageing and Development, 2008)

Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and apoptosis - Almeida, T.; Marques, M.; Mojzita, D.; Amorim, M.A.; Silva, R.D.; Almeida, B.; Rodrigues, P.; Ludovico, P.; Hohmann, S.; Moradas-Ferreira, P.; Côrte-Real, M.; Costa, V. (Molecular Biology of the Cell, 2008)

Protein oxidation, repair mechanisms and proteolysis in Saccharomyces cerevisiae - Costa, V.; Quintanilha, A.; Moradas-Ferreira, P. (IUBMB Life, 2007)

Quercetin increases oxidative stress resistance and longevity in Saccharomyces cerevisiae - Belinha, I.; Amorim, M.A.; Rodrigues, P.; de Freitas, V.; Moradas-Ferreira, P.; Mateus, N.; Costa, V. (Journal of Agricultural and Food Chemistry, 2007)

The Pep4p vacuolar proteinase contributes to the turnover of oxidized proteins but PEP4 overexpression is not sufficient to increase chronological lifespan in Saccharomyces cerevisiae - Marques, M.; Mojzita, D.; Amorim, M.A.; Almeida, T.; Hohmann, S.; Moradas-Ferreira, P.; Costa, V. (Microbiology, 2006)

Overexpressed Sod1p acts either to reduce or to increase the lifespans and stress resistance of yeast, depending on whether it is Cu2+-deficient or an active Cu,Zn-superoxide dismutase - Harris, N.; Bachler, M.; Costa, V.; Mollapour, M.; Moradas-Ferreira, P.; Piper, P.W. (Aging Cell, 2005)