Chroman-4-one derivatives targeting pteridine reductase 1 and showing anti-parasitic activity - Di Pisa, F.; Landi, G.; Dello Iacono, L.; Pozzi, C.; Borsari, C.; Ferrari, S.; Santucci, M.; Santarém, N.; Cordeiro-da-Silva, A.; Moraes, C.B.; Alcantara, L.M.; Fontana, V.; et al. (Molecules, 2017)

In vivo imaging of pathogen homing to the host tissues - Tavares, J.; Costa, D.M.; Teixeira, A.R.; Cordeiro-da-Silva, A.; Amino, R. (Methods, 2017)

Infection of hematopoietic stem cells by Leishmania infantum increases erythropoiesis and alters the phenotypic and functional profiles of progeny - Carvalho-Gontijo, R.; Moreira, D.R.; Resende, M.; Costa-Silva, M.F.; Peruhype-Magalhães, V.; Ribeiro, C.M.F.; Ribeiro, D.D.; Silvestre, R.; Cordeiro-da-Silva, A.; Martins-Filho, O.A.; Teixeira-Carvalho, A. (Cellular Immunology, 2017)

Leishmania infantum exoproducts inhibit human invariant NKT cell expansion and activation - Belo, R.; Santarém, N.; Pereira, C.; Pérez-Cabezas, B.; Macedo, F.; Leite-de-Moraes, M.; Cordeiro-da-Silva, A. (Frontiers in Immunology, 2017)

Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds - Borsari, C.; Santarém, N.; Torrado, J.; Olías, A.I.; Corral, M.J.; Baptista, C.; Gul, S.; Wolf, M.; Kuzikov, M.; Ellinger, B.; Witt, G.; Gribbon, P.; et al. (European Journal of Medicinal Chemistry, 2017)

Pre-clinical antigenicity studies of an innovative multivalent vaccine for human visceral leishmaniasis - Cecílio, P.; Pérez-Cabezas, B.; Fernandez, L.; Moreno, J.; Carrillo, E.; Requena, J.M.; Fichera, E.; Reed, S.G.; Coler, R.N.; Kamhawi, S.; Oliveira, F.; Valenzuela, J.G.; et al. (PLoS Neglected Tropical Diseases, 2017)

Activity of bisnaphthalimidopropyl derivatives against trypanosoma brucei - Graça, N.A.G.; Gaspar, L.; Costa, D.M.; Loureiro, I.; Thoo-Lin, P.K.; Ramos, I.; Roura, M.; Pruvost, A.; Pemberton, I.K.; Loukil, H.; Macdougall, J.; Tavares, J.; et al. (Antimicrobial Agents and Chemotherapy, 2016)

AMP-activated protein kinase as a target for pathogens: Friends or foes? - Moreira, D.; Silvestre, R.; Cordeiro-da-Silva, A.; Estaquier, J.; Foretz, M.; Viollet, B. (Current Drug Targets, 2016)

AMPK in Pathogens - Mesquita, I.; Moreira, D.; Sampaio-Marques, B.; Laforge, M.; Cordeiro-da-Silva, A.; Ludovico, P.; Estaquier, J.; Silvestre, R. (EXS, 2016)

Development and validation of HPLC method with fluorometric detection for quantification of bisnaphthalimidopropyldiaminooctane in animal tissues following administration in polymeric nanoparticles - Segundo, M.A.; Abreu, V.L.R.G.; Osório, M.V.; Nogueira, S.; Lin, P.K.T.; Cordeiro-da-Silva, A.; Lima, S.A.C. (Journal of Pharmaceutical and Biomedical Analysis, 2016)

Disclosing the essentiality of ribose-5-phosphate isomerase B in Trypanosomatids - Faria, J.; Loureiro, I.; Santarém, N.; Ceclio, P.; Macedo-Ribeiro, S.; Tavares, J.; Cordeiro-da-Silva, A. (Scientific Reports, 2016)

Interleukin-27 early impacts Leishmania infantum infection in mice and correlates with active visceral disease in humans - Pérez-Cabezas, B.; Cecílio, P.; Robalo, A.L.; Silvestre, R.; Carrillo, E.; Moreno, J.; San Martín, J.V.; Vasconcellos, R.; Cordeiro-da-Silva, A. (Frontiers in Immunology, 2016)

Leishmania infantum Asparagine Synthetase A Is Dispensable for Parasites Survival and Infectivity - Faria, J.; Loureiro, I.; Santarém, N.; Macedo-Ribeiro, S.; Tavares, J.; Cordeiro-da-Silva, A. (PLoS Neglected Tropical Diseases, 2016)

Poly-N-acetylglucosamine production by Staphylococcus epidermidis cells increases their in vivo proinflammatory effect - Ferreirinha, P.; Pérez-Cabezas, B.; Correia, A.; Miyazawa, B.; França, Â.; Carvalhais, V.; Faustino, A.; Cordeiro-da-Silva, A.; Teixeira, L.; Pier, G.B.; Cerca, N.; Vilanova, M. (Infection and Immunity, 2016)

Profiling of flavonol derivatives for the development of antitrypanosomatidic drugs - Borsari, C.; Lucian, R.; Pozzi, C.; Poehner, I.; Henrich, S.; Trande, M.; Cordeiro-da-Silva, A.; Santarém, N.; Baptista, C.; Tait, A.; Di Pisa, F.; Iacono, L.D.; et al. (Journal of Medicinal Chemistry, 2016)

Regulation of immunity during visceral Leishmania infection - Rodrigues, V.; Cordeiro-da-Silva, A.; Laforge, M.; Silvestre, R.; Estaquier, J. (Parasites and Vectors, 2016)

Drug discovery for human African trypanosomiasis: Identification of novel scaffolds by the newly developed HTS SYBR green assay for trypanosoma brucei - Faria, J.; Moraes, C.B.; Song, R.; Pascoalino, B.S.; Lee, N.; Siqueira-Neto, J.L.; Cruz, D.J.M.; Parkinson, T.; Ioset, J.-R.; Cordeiro-da-Silva, A.; Freitas-Junior, L.H. (Journal of Biomolecular Screening, 2015)

Enantiomers of nifurtimox do not exhibit stereoselective anti-Trypanosoma cruzi activity, toxicity, or pharmacokinetic properties - Moraes, C.B.; White, K.L.; Braillard, S.; Perez, C.; Goo, J.; Gaspar, L.; Shackleford, D.M.; Cordeiro-da-Silva, A.; Thompson, R.C.A.; Freitas-Junior, L.; Charman, S.A.; Chatelain, E. (Antimicrobial Agents and Chemotherapy, 2015)

Surface functionalization of polymeric nanospheres modulates macrophage activation: Relevance in Leishmaniasis therapy - Barros, D.; Lima, S.A.C.; Cordeiro-da-Silva, A. (Nanomedicine, 2015)

Exoproteome dynamics in Leishmania infantum - Santarém, N.; Racine, G.; Silvestre, R.; Cordeiro-da-Silva, A.; Ouellette, M. (Journal of Proteomics, 2013)

Prevalence of antibodies to Leishmania infantum and Toxoplasma gondii in horses from the north of Portugal - Lopes, A.P.; Sousa, S.; Dubey, J.; Ribeiro, A.J.; Silvestre, R.; Cotovio, M.; Schallig, H.D.F.H.; Cardoso, L.; Cordeiro-da-Silva, A. (Parasites and Vectors, 2013)

TLR2-induced IL-10 production impairs neutrophil recruitment to infected tissues during neonatal bacterial sepsis - Andrade, E.B.; Alves, J.; Madureira, P.; Oliveira, L.; Ribeiro, A.; Cordeiro-da-Silva, A.; Correia-Neves, M.; Trieu-Cuot, P.; Ferreira, P. (Journal of Immunology, 2013)

Ultrasonication of insulin-loaded microgel particles produced by internal gelation: Impact on particle's size and insulin bioactivity - Santos, A.C.; Cunha, J.; Veiga, F.; Cordeiro-da-Silva, A.; Ribeiro, A.J. (Carbohydrate Polymers, 2013)

Anti-leishmanial activity of the bisnaphthalimidopropyl derivatives - Tavares, J.; Ouaissi, A.; Silva, A.M.; Lin, P.K.T.; Roy, N.; Cordeiro-da-Silva, A. (Parasitology International, 2012)

Characterization of Leishmania infantum thiol-dependent reductase 1 and evaluation of its potential to induce immune protection - Silva, A.M.; Tavares, J.; Silvestre, R.; Ouaissi, A.; Coombs, G. H.; Cordeiro-da-Silva, A. (Parasite Immunology, 2012)

Human periprostatic white adipose tissue is rich in stromal progenitor cells and a potential source of prostate tumor stroma - Ribeiro, R.; Monteiro, C.; Silvestre, R.; Castela, A.; Coutinho, H.; Fraga, A.; Príncipe, P.; Lobato, C.; Costa, C.; Cordeiro-da-Silva, A.; Lopes, J. M.; Lopes, C.; et al. (Experimental Biology and Medicine, 2012)

Impact of continuous axenic cultivation in Leishmania infantum virulence - Moreira, D.; Santarém, N.; Loureiro, I.; Tavares, J.; Silva, A.M.; Amorim, A.M.; Ouaissi, A.; Cordeiro-da-Silva, A.; Silvestre, R. (PLoS Neglected Tropical Diseases, 2012)

Modulation of mammalian apoptotic pathways by intracellular protozoan parasites - Rodrigues, V.; Cordeiro-da-Silva, A.; Laforge, M.; Ouaissi, A.; Silvestre, R.; Estaquier, J. (Cellular Microbiology, 2012)

Solid lipid nanoparticles as intracellular drug transporters: An investigation of the uptake mechanism and pathway - Martins, S.; Costa-Lima, S.; Carneiro, T.; Cordeiro-da-Silva, A.; Souto, E.B.; Ferreira, D. C. (International Journal of Pharmaceutics, 2012)

In vitro study of P-glycoprotein induction as an antidotal pathway to prevent cytotoxicity in Caco-2 cells - Silva, R.; Carmo, H.; Dinis-Oliveira, R.; Cordeiro-da-Silva, A.; Lima, S.C.; Carvalho, F.; de Lourdes Bastos, M.; Remião, F. (Archives of Toxicology, 2011)

The Leishmania nicotinamidase is essential for NAD + production and parasite proliferation - Gazanion, E.; Garcia, D.; Silvestre, R.; Gérard, C.; Guichou, J.F.; Labesse, G.; Seveno, M.; Cordeiro-da-Silva, A.; Ouaissi, A.; Sereno, D.; Vergnes, B. (Molecular Microbiology, 2011)

P-glycoprotein activity in human Caucasian male lymphocytes does not follow its increased expression during aging - Vilas-Boas, V.; Silva, R.; Gaio, A.R.; Martins, A.M.; Lima, S.C.; Cordeiro-da-Silva, A.; de Lourdes Bastos, M.; Remião, F. (Cytometry Part A, 2011)

Proinflammatory environment dictates the IL-17-producing capacity of human invariant NKT cells - Moreira-Teixeira, L.; Resende, M.; Coffre, M.; Devergne, O.; Herbeuval, J.-P.; Hermine, O.; Schneider, E.; Rogge, L.; Ruemmele, F.M.; Dy, M.; Cordeiro-da-Silva, A.; Leite-de-Moraes, M.C. (Journal of Immunology, 2011)

Application of an improved enzyme-linked immunosorbent assay method for serological diagnosis of canine leishmaniasis - Santarém, N.; Silvestre, R.; Cardoso, L.; Schallig, H.; Reed, S.G.; Cordeiro-da-Silva, A. (Journal of Clinical Microbiology, 2010)

In vitro and in vivo anticancer activity of a novel nano-sized formulation based on self-assembling polymers against pancreatic cancer - Lin, P.K.T.; Hoskins, C.; Ouaissi, M.; Lima, S.C.; Cheng, W.P.; Loureirio, I.; Mas, E.; Lombardo, D.; Cordeiro-da-Silva, A.; Ouaissi, A. (Pharmaceutical Research, 2010)

Bisnaphthalimidopropyl derivatives as inhibitors of Leishmania SIR2 related protein 1 - Tavares, J.; Ouaissi, A.; Lin, P.K.T.; Loureiro, I.; Kaur, S.; Roy, N.; Cordeiro-da-Silva, A. (ChemMedChem, 2009)

The contribution of Toll-like receptor 2 to the innate recognition of a Leishmania infantum silent information regulator 2 protein - Silvestre, R.; Silva, A.M.; Cordeiro-da-Silva, A.; Ouaissi, A. (Immunology, 2009)

Evaluation of Leishmania species reactivity in human serologic diagnosis of leishmaniasis - Silvestre, R.; Santarém, N.; Teixeira, L.; Cunha, J.; Schallig, H.; Cordeiro-da-Silva, A. (American Journal of Tropical Medicine and Hygiene, 2009)

Recognition of Leishmania parasites by innate immunity - Silvestre, R.; Santarém, N.; Tavares, J.; Silva, A.M.; Cordeiro-da-Silva, A. (Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry, 2009)

Alginate coated chitosan nanoparticles are an effective subcutaneous adjuvant for hepatitis B surface antigen - Borges, O.; Silva, M.; de Sousa, A.; Borchard, G.; Junginger, H.E.; Cordeiro-da-Silva, A. (International Immunopharmacology, 2008)

Benzodiazepine-mediated structural changes in the multidrug transporter P-glycoprotein: An intrinsic fluorescence quenching analysis - Lima, S.A.C.; Cordeiro-da-Silva, A.; de Castro, B.; Gameiro, P. (Journal of Membrane Biology, 2008)

Effect of nonsteroidal anti-inflammatory drugs on the cellular membrane fluidity - Sousa, C.; Nunes, C.; Lúcio, M.; Ferreira, H.; Lima, J.L.F.C.; Tavares, J.; Cordeiro-da-Silva, A.; Reis, S. (Journal of Pharmaceutical Sciences, 2008)

Flurazepam inhibits the P-glycoprotein transport function: An insight to revert multidrug-resistance phenotype - Lima, S.A.C.; Tavares, J.; Gameiro, P.; de Castro, B.; Cordeiro-da-Silva, A. (European Journal of Pharmacology, 2008)

Immune response by nasal delivery of hepatitis B surface antigen and codelivery of a CpG ODN in alginate coated chitosan nanoparticles - Borges, O.; Cordeiro-da-Silva, A.; Tavares, J.; Santarém, N.; de Sousa, A.; Borchard, G.; Junginger, H.E. (European Journal of Pharmaceutics and Biopharmaceutics, 2008)

The Leishmania infantum cytosolic SIR2-related protein 1 (LiSIR2RP1) is an NAD+-dependent deacetylase and ADP-ribosyltransferase - Tavares, J.; Ouaissi, A.; Santarém, N.; Sereno, D.; Vergnes, B.; Sampaio, P.; Cordeiro-da-Silva, A. (Biochemical Journal, 2008)

A Leishmania infantum cytosolic tryparedoxin activates B cells to secrete interleukin-10 and specific immunoglobulin - Menezes Cabral, S.; Leal Silvestre, R.; Moreira Santarém, N.; Costa Tavares, J.; Franco Silva, A.; Cordeiro-da-Silva, A. (Immunology, 2008)

Live attenuated Leishmania vaccines: A potential strategic alternative - Silvestre, R.; Cordeiro-da-Silva, A.; Ouaissi, A. (Archivum Immunologiae et Therapiae Experimentalis, 2008)

Serological evaluation of experimentally infected dogs by LicTXNPx-ELISA and amastigote-flow cytometry - Silvestre, R.; Santarém, N.; Cunha, J.; Cardoso, L.; Nieto, J.; Carrillo, E.; Moreno, J.; Cordeiro-da-Silva, A. (Veterinary Parasitology, 2008)

Substituted phenols as pollutants that affect membrane fluidity - Nunes, C.; Sousa, C.; Ferreira, H.; Lucio, M.; Lima, J.L.F.C.; Tavares, J.; Cordeiro-da-Silva, A.; Reis, S. (Journal of Environmental Biology, 2008)

Therapy and further development of anti-leishmanial drugs - da Costa Tavares, J.A.P.; Ouaissi, A.; Cordeiro-da-Silva, A. (Current Drug Therapy, 2008)

Anti-Leishmania humoral and cellular immune responses in naturally infected symptomatic and asymptomatic dogs - Cardoso, L.; Schallig, H.D.F.H.; Cordeiro-da-Silva, A.; Cabral, M.; Alunda, J.M.; Rodrigues, M. (Veterinary Immunology and Immunopathology, 2007)

Characterization of the anti-Leishmania effect induced by cisplatin, an anticancer drug - Tavares, J.; Ouaissi, M.; Ouaissi, A.; Cordeiro-da-Silva, A. (Acta Tropica, 2007)

Evaluation of the immune response following a short oral vaccination schedule with hepatitis B antigen encapsulated into alginate-coated chitosan nanoparticles - Borges, O.; Tavares, J.; de Sousa, A.; Borchard, G.; Junginger, H.E.; Cordeiro-da-Silva, A. (European Journal of Pharmaceutical Sciences, 2007)

Immune response regulation by Leishmania secreted and nonsecreted antigens - Santarém, N.; Silvestre, R.; Tavares, J.; Silva, M.; Cabral, S.; Maciel, J.; Cordeiro-da-Silva, A. (Journal of Biomedicine and Biotechnology, 2007)

Induction of lymphocytes activated marker CD69 following exposure to chitosan and alginate biopolymers - Borges, O.; Borchard, G.; de Sousa, A.; Junginger, H.E.; Cordeiro-da-Silva, A. (International Journal of Pharmaceutics, 2007)

Molecular karyotype analysis of Perkinsus atlanticus (Phylum Perkinsozoa) by pulsed field gel electrophoresis - Leonor Teles-Grilo, M.; Duarte, S.M; Tato-Costa, J.; Gaspar-Maia, A.; Oliveira, C.; Rocha, A.A; Marques, A.; Cordeiro-da-Silva, A.; Azevedo, C. (European Journal of Protistology, 2007)

Sensitivity of P-glycoprotein tryptophan residues to benzodiazepines and ATP interaction - Lima, S.A.C.; Cordeiro-da-Silva, A.; de Castro, B.; Gameiro, P. (Biophysical Chemistry, 2007)

SIR2-deficient Leishmania infantum induces a defined IFN-γ/IL-10 pattern that correlates with protection - Silvestre, R.; Cordeiro-da-Silva, A.; Santarém, N.; Vergnes, B.; Sereno, D.; Ouaissi, A. (Journal of Immunology, 2007)

Leishmania cytosolic silent information regulatory protein 2 deacetylase induces murine B-cell differentiation and in vivo production of specific antibodies - Silvestre, R.; Cordeiro-da-Silva, A.; Tavares, J.; Sereno, D.; Ouaissi, A. (Immunology, 2006)

Uptake studies in rat Peyer's patches, cytotoxicity and release studies of alginate coated chitosan nanoparticles for mucosal vaccination - Borges, O.; Cordeiro-da-Silva, A.; Romeijn, S.G.; Amidi, M.; de Sousa, A.; Borchard, G.; Junginger, H.E. (Journal of Controlled Release, 2006)

Antibodies against a Leishmania infantum peroxiredoxin as a possible marker for diagnosis of visceral leishmaniasis and for monitoring the efficacy of treatment - Santarém, N.; Tomás, A.; Ouaissi, A.; Tavares, J.; Ferreira, N.; Manso, A.; Campino, L.; Correia, J.M.; Cordeiro-da-Silva, A. (Immunology Letters, 2005)

Differential effects of polyamine derivative compounds against Leishmania infantum promastigotes and axenic amastigotes - Tavares, J.; Ouaissi, A.; Lin, P.K.T.; Tomás, A.; Cordeiro-da-Silva, A. (International Journal for Parasitology, 2005)

Effect of anti-inflammatory drugs on splenocyte membrane fluidity - Ferreira, H.; Lúcio, M.; Lima, J.L.F.C.; Cordeiro-da-Silva, A.; Tavares, J.; Reis, S. (Analytical Biochemistry, 2005)

A method for functional mouse MDR3 P-glycoprotein reconstitution in Escherichia coli lipids - Lima, S.A.C.; Cordeiro-da-Silva, A.; Gameiro, P.; de Castro, B. (Analytical Biochemistry, 2005)

Targeted disruption of cytosolic SIR2 deacetylase discloses its essential role in Leishmania survival and proliferation - Vergnes, B.; Sereno, D.; Tavares, J.; Cordeiro-da-Silva, A.; Vanhille, L.; Madjidian-Sereno, N.; Depoix, D.; Monte-Alegre, A.; Ouaissi, A. (Gene, 2005)

Effect of abietane diterpenes from Plectranthus grandidentatus on T- and B-lymphocyte proliferation - Cerqueira, F.; Cordeiro-da-Silva, A.; Gaspar-Marques, C.; Simões, F.; Pinto, M.M.M.; Nascimento, M.S.J. (Bioorganic and Medicinal Chemistry, 2004)

Host cell phenotypic variability induced by trypanosomatid-parasite- released immunomodulatory factors: Physiopathological implications - Ouaissi, A.; Ouaissi, M.; Tavares, J.; Cordeiro-da-Silva, A. (Journal of Biomedicine and Biotechnology, 2004)

Immunological alterations induced by polyamine derivatives on murine splenocytes and human mononuclear cells - Cordeiro-da-Silva, A.; Tavares, J.; Araújo, N.; Cerqueira, F.; Tomás, A.; Lin, P.K.T.; Ouaissi, A. (International Immunopharmacology, 2004)

Two linked genes of Leishmania infantum encode tryparedoxins localised to cytosol and mitochondrion - Castro, H.; Sousa, C.; Novais, M.; Santos, M.; Budde, H.; Cordeiro-da-Silva, A.; Flohé, L.; Tomás, A.M. (Molecular and Biochemical Parasitology, 2004)