%0 Journal Article %J Biochimica et Biophysica Acta - Gene Regulatory Mechanisms %D 2017 %T Expression of Rac1 alternative 3′ UTRs is a cell specific mechanism with a function in dendrite outgrowth in cortical neurons %A Braz, S.O. %A Cruz, A. %A Lobo, A. %A Bravo, J. %A Moreira-Ribeiro, J. %A Pereira-Castro, I. %A Freitas, J. %A Relvas, J.B. %A Summavielle, T. %A Moreira, A. %B Biochimica et Biophysica Acta - Gene Regulatory Mechanisms %V 1860 %P 685 - 694 %8 2017 %G eng %U https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018940086&doi=10.1016%2fj.bbagrm.2017.03.002&partnerID=40&md5=497c8b1050eb2fdb6581e5c08b1def3d %N 6 %0 Journal Article %J Laboratory Animals %D 2017 %T Ketamine alone or combined with midazolam or dexmedetomidine does not affect anxiety-like behaviours and memory in adult wistar rats %A Magalhães, A. %A Valentim, A. %A Venâncio, C. %A Pereira, M. %A Melo, P. %A Summavielle, T. %A Antunes, L. %B Laboratory Animals %V 51 %P 147 - 159 %8 2017 %G eng %U https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018396469&doi=10.1177%2f0023677216652380&partnerID=40&md5=568cf19b87c443932408ce7edd0b9114 %N 2 %0 Journal Article %J Molecular Neurobiology %D 2016 %T Acetyl-L-Carnitine Prevents Methamphetamine-Induced Structural Damage on Endothelial Cells via ILK-Related MMP-9 Activity %A Fernandes, S. %A Salta, S. %A Bravo, J. %A Silva, A.P. %A Summavielle, T. %B Molecular Neurobiology %V 53 %P 408 - 422 %8 2016 %G eng %U https://www.scopus.com/inward/record.uri?eid=2-s2.0-84953357442&doi=10.1007%2fs12035-014-8973-5&partnerID=40&md5=c7a500b7d02fdfde5360ce4b1290dac9 %N 1 %0 Journal Article %J PLoS ONE %D 2016 %T Bone injury and repair trigger central and peripheral NPY neuronal pathways %A Alves, C.J. %A Alencastre, I.S. %A Neto, E. %A Ribas, J. %A Ferreira, S. %A Vasconcelos, D.M. %A Sousa, D.M. %A Summavielle, T. %A Lamghari, M. %B PLoS ONE %V 11 %8 2016 %G eng %U https://www.scopus.com/inward/record.uri?eid=2-s2.0-84993996075&doi=10.1371%2fjournal.pone.0165465&partnerID=40&md5=e720ae31dd9e9a62df027838849730c0 %N 11 %0 Journal Article %J Anesthesia and Analgesia %D 2016 %T In Response %A Summavielle, T. %A Venâncio, C. %A Antunes, L. %B Anesthesia and Analgesia %V 122 %P 918 - 920 %8 2016 %G eng %U https://www.scopus.com/inward/record.uri?eid=2-s2.0-84959042892&doi=10.1213%2fANE.0000000000001001&partnerID=40&md5=497eae88eb82cc9889399d62ca4eb148 %N 3 %0 Journal Article %J Cellular and Molecular Life Sciences %D 2016 %T Methylphenidate-triggered ROS generation promotes caveolae-mediated transcytosis via Rac1 signaling and c-Src-dependent caveolin-1 phosphorylation in human brain endothelial cells %A Coelho-Santos, V. %A Socodato, R. %A Portugal, C. %A Leitão, R.A. %A Rito, M. %A Barbosa, M. %A Couraud, P.-O. %A Romero, I.A. %A Weksler, B. %A Minshall, R.D. %A Fontes-Ribeiro, C. %A Summavielle, T. %A Relvas, J.B. %A Silva, A.P. %B Cellular and Molecular Life Sciences %V 73 %P 4701 - 4716 %8 2016 %G eng %U https://www.scopus.com/inward/record.uri?eid=2-s2.0-84976878471&doi=10.1007%2fs00018-016-2301-3&partnerID=40&md5=81271ade7b838b8d0b3523089c18ffaf %N 24 %0 Journal Article %J Anesthesia and Analgesia %D 2015 %T Acute ketamine impairs mitochondrial function and promotes superoxide dismutase activity in the rat brain %A Venâncio, C. %A Félix, L. %A Almeida, V. %A Coutinho, J. %A Antunes, L. %A Peixoto, F. %A Summavielle, T. %B Anesthesia and Analgesia %V 120 %P 320 - 328 %8 2015 %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-84922337300&partnerID=40&md5=66dfbfba4414d4835d8c6a64d3ae47b5 %N 2 %0 Journal Article %J RSC Advances %D 2015 %T Biology-oriented development of novel lipophilic antioxidants with neuroprotective activity %A Silva, T. %A Bravo, J. %A Summavielle, T. %A Remião, F. %A Pérez, C. %A Gil, C. %A Martínez, A. %A Borges, F. %B RSC Advances %V 5 %P 15800 - 15811 %8 2015 %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-84922828018&partnerID=40&md5=a6366f72d8c4f3ea25614aff7c596b17 %N 21 %0 Journal Article %J MedChemComm %D 2015 %T Exploring cinnamic acid scaffold: development of promising neuroprotective lipophilic antioxidants %A Chavarria, D. %A Silva, T. %A Martins, D. %A Bravo, J. %A Summavielle, T. %A Garrido, J. %A Borges, F. %B MedChemComm %V 6 %P 1043 - 1053 %8 2015 %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-84935895324&partnerID=40&md5=ad247dd80c40723624417a1d9d599e47 %N 6 %0 Journal Article %J Toxicology Letters %D 2015 %T Methamphetamine promotes α-tubulin deacetylation in endothelial cells: The protective role of acetyl-l-carnitine %A Fernandes, S. %A Salta, S. %A Summavielle, T. %B Toxicology Letters %V 234 %P 131 - 138 %8 2015 %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-84923364136&partnerID=40&md5=6976054fcfdef28a06ef77049d993b99 %N 2 %0 Journal Article %J Life Sciences %D 2013 %T Chronic ketamine administration impairs mitochondrial complex i in the rat liver %A Venâncio, C. %A Antunes, L. %A Félix, L. %A Rodrigues, P. %A Summavielle, T. %A Peixoto, F. %B Life Sciences %V 93 %P 464 - 470 %8 2013 %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-84884202630&partnerID=40&md5=49ecbdf53d56fa1eb802d09527740c4e %N 12-14 %0 Journal Article %J Addiction Biology %D 2012 %T Adolescent pre-exposure to ethanol and 3,4-methylenedioxymethylamphetamine (MDMA) increases conditioned rewarding effects of MDMA and drug-induced reinstatement %A Ribeiro Do Couto, B. %A Daza-Losada, M. %A Rodríguez-Arias, M. %A Nadal, R. %A Guerri, C. %A Summavielle, T. %A Miñarro, J. %A Aguilar, M. A. %B Addiction Biology %V 17 %P 588 - 600 %8 2012/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-84860240599&partnerID=40&md5=d4c3cd9c174173d4011ad4e6f980de44 %N 3 %0 Journal Article %J NeuroToxicology %D 2012 %T Methamphetamine mimics the neurochemical profile of aging in rats and impairs recognition memory %A Melo, P. %A Magalhães, A. %A Alves, C.J. %A Tavares, M.A. %A de Sousa, L. %A Summavielle, T. %A Moradas-Ferreira, P. %B NeuroToxicology %V 33 %P 491 - 499 %8 2012/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-84861188767&partnerID=40&md5=9c50ef658007fb37150c8b2d6d235d29 %N 3 %0 Journal Article %J Neuropharmacology %D 2012 %T Neuropeptide y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures %A Baptista, S. %A Bento, A.R. %A Gonalves, J. %A Bernardino, L. %A Summavielle, T. %A Lobo, A. %A Fontes-Ribeiro, C. %A Malva, J.O. %A Agasse, F. %A Silva, A.P. %B Neuropharmacology %V 62 %P 2412 - 2422 %8 2012/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-84859111071&partnerID=40&md5=9a21ed4866bb61cdfefda5275553e1bb %N 7 %0 Journal Article %J Current Neuropharmacology %D 2011 %T Impaired spatial memory after ketamine administration in chronic low doses %A Venâncio, C. %A Magalhães, A. %A Antunes, L. %A Summavielle, T. %B Current Neuropharmacology %V 9 %P 251 - 255 %8 2011/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-79953036071&partnerID=40&md5=8a78505e05ec9225b32deafac93cb809 %N 1 %0 Journal Article %J Neuroscience %D 2010 %T Monoamine deficits in the brain of methyl-CpG binding protein 2 null mice suggest the involvement of the cerebral cortex in early stages of Rett syndrome %A Santos, M. %A Summavielle, T. %A Teixeira-Castro, A. %A Silva-Fernandes, A. %A Duarte-Silva, S. %A Marques, F. %A Martins, L. %A Dierssen, M. %A Oliveira, P. %A Sousa, N. %A MacIel, P. %B Neuroscience %V 170 %P 453 - 467 %8 2010/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-77956186732&partnerID=40&md5=ad8748ce63b7d0622c34c41bb804d822 %N 2 %0 Journal Article %J Neuroscience %D 2009 %T Acetyl-l-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain %A Alves, E. %A Binienda, Z. %A Carvalho, F. %A Alves, C.J. %A Fernandes, E. %A de Lourdes Bastos, M. %A Tavares, M.A. %A Summavielle, T. %B Neuroscience %V 158 %P 514 - 523 %8 2009/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-58149463913&partnerID=40&md5=6810fd8973ec6d1ef28edfcd53372d46 %N 2 %0 Journal Article %J Addiction Biology %D 2009 %T Ecstasy-induced oxidative stress to adolescent rat brain mitochondria in vivo: Influence of monoamine oxidase type A %A Alves, E. %A Summavielle, T. %A Alves, C.J. %A Custódio, J.B.A. %A Fernandes, E. %A de Lourdes Bastos, M. %A Tavares, M.A. %A Carvalho, F. %B Addiction Biology %V 14 %P 185 - 193 %8 2009/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-61849137910&partnerID=40&md5=acf6481aa19f18e5d4e176381aadf2ee %N 2 %0 Book %B Annals of the New York Academy of Sciences %D 2008 %T Exploratory behavior in rats postnatally exposed to cocaine and housed in an enriched environment %A Magalhães, A. %A Melo, P. %A Alves, C.J. %A Tavares, M.A. %A de Sousa, L. %A Summavielle, T. %B Annals of the New York Academy of Sciences %V 1139 %P 358 - 365 %8 2008/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-53549102243&partnerID=40&md5=11117e3088faca502f734ca72b2cd134 %0 Book %B Annals of the New York Academy of Sciences %D 2008 %T Hormonal, neurochemical, and behavioral response to a forced swim test in adolescent rats throughout cocaine withdrawal %A Alves, C.J. %A Magalhães, A. %A Summavielle, T. %A Melo, P. %A de Sousa, L. %A Tavares, M.A. %A Monteiro, P.R.R. %B Annals of the New York Academy of Sciences %V 1139 %P 366 - 373 %8 2008/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-53549107231&partnerID=40&md5=0d815f63d81aa34bb11e35fd96763351 %0 Journal Article %J Journal of Neuroscience %D 2007 %T Monoamine oxidase-B mediates ecstasy-induced neurotoxic effects to adolescent rat brain mitochondria %A Alves, E. %A Summavielle, T. %A Alves, C.J. %A Gomes-da-Silva, J. %A Barata, J.C. %A Fernandes, E. %A Bastos, M.D.L. %A Tavares, M.A. %A Carvalho, F. %B Journal of Neuroscience %V 27 %P 10203 - 10210 %8 2007/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-34548842751&partnerID=40&md5=8295b49602a0a44f030a5b162beaa762 %N 38 %0 Journal Article %J Neuroscience %D 2007 %T Neurodevelopment milestone abnormalities in rats exposed to stress in early life %A Mesquita, A.R. %A Pêgo, J.M. %A Summavielle, T. %A MacIel, P. %A Almeida, O.F.X. %A Sousa, N. %B Neuroscience %V 147 %P 1022 - 1033 %8 2007/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-34547102233&partnerID=40&md5=4ba7f87346216b09c5276bc485388b50 %N 4 %0 Journal Article %J Human and Experimental Toxicology %D 2007 %T Postnatal exposure to cocaine in rats housed in an enriched environment: Effects on social interactions %A Magalhães, A. %A Summavielle, T. %A Tavares, M.A. %A de Sousa, L. %B Human and Experimental Toxicology %V 26 %P 303 - 309 %8 2007/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-34248345906&partnerID=40&md5=6db885507cf551cd23ff668d370191a8 %N 4 %0 Book %B Annals of the New York Academy of Sciences %D 2006 %T MDMA in adolescent male rats: Decreased serotonin in the amygdala and behavioral effects in the elevated plus-maze test %A Faria, R. %A Magalhães, A. %A Monteiro, P.R.R. %A Gomes-da-Silva, J. %A Tavares, M.A. %A Summavielle, T. %B Annals of the New York Academy of Sciences %V 1074 %P 643 - 649 %8 2006/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-33749555776&partnerID=40&md5=b1830a0899cadc4874c77a04bfbfd66c %0 Book %B Annals of the New York Academy of Sciences %D 2006 %T Prenatal exposure to cocaine and enriched environment: Effects on social interactions %A Magalhães, A. %A Summavielle, T. %A Melo, P. %A Rosa, R. %A Tavares, M.A. %A de Sousa, L. %B Annals of the New York Academy of Sciences %V 1074 %P 620 - 631 %8 2006/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-33749542491&partnerID=40&md5=300152d48ec8b54545813b8493e436c2 %0 Journal Article %J Environmental Toxicology and Pharmacology %D 2005 %T Prenatal cocaine exposure: Effects on locomotor activity in rat offspring %A Magalhães, A. %A Summavielle, T. %A Melo, P. %A Tavares, M.A. %A de Sousa, L. %B Environmental Toxicology and Pharmacology %V 19 %P 767 - 773 %8 2005/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-17044425030&partnerID=40&md5=5dea35b1e9102b442981a689b0423f44 %N 3 %0 Book %B Annals of the New York Academy of Sciences %D 2004 %T Abnormal immunoreactivity to serotonin in cerebellar purkinje cells after neonatal cocaine exposure %A Summavielle, T. %A Alves, C.J. %A Monteiro, P.R.R. %A Tavares, M.A. %B Annals of the New York Academy of Sciences %V 1025 %P 630 - 637 %8 2004/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-10444279249&partnerID=40&md5=838f8e97480ae090fe27c4241bec0e81 %0 Book %B Annals of the New York Academy of Sciences %D 2004 %T Effects of neonatal exposure to methamphetamine: Catecholamine levels in brain areas of the developing rat %A Gomes-da-Silva, J. %A De Miguel, R. %A Fernández-Ruiz, J. %A Summavielle, T. %A Tavares, M.A. %B Annals of the New York Academy of Sciences %V 1025 %P 602 - 611 %8 2004/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-10444268132&partnerID=40&md5=f2558f78b733645acd71adeb7cdef50b %0 Book %B Annals of the New York Academy of Sciences %D 2004 %T Effects of postnatal cocaine exposure and environmental enrichment on rat behavior in a forced swim test %A Magalhães, A. %A Summavielle, T. %A Tavares, M.A. %A de Sousa, L. %B Annals of the New York Academy of Sciences %V 1025 %P 619 - 629 %8 2004/// %G eng %U http://www.scopus.com/inward/record.url?eid=2-s2.0-10444275641&partnerID=40&md5=b9a404ada86742d31c648c752629fd24