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Author Title [ Type(Desc)] Year
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Journal Article
Leal, S. S., Cristóvão, J. S., Biesemeier, A., Cardoso, I., & Gomes, C. M. (2015). Aberrant zinc binding to immature conformers of metal-free copper-zinc superoxide dismutase triggers amorphous aggregation. Metallomics, 7(2), 333 - 346.
Monteiro, F. A., Sousa, M. M., Cardoso, I., Do Amaral, J. B., et al. (2006). Activation of ERK1/2 MAP kinases in familial amyloidotic polyneuropathy. Journal of Neurochemistry, 97(1), 151 - 161.
Santos, S. D., Costa, R., Teixeira, P. F., Gottesman, M., et al. (2008). Amyloidogenic properties of transthyretin-like protein (TLP) from Escherichia coli. FEBS Letters, 582(19), 2893 - 2898.
Ferreira, N., Cardoso, I., Domingues, M. R., Vitorino, R., et al. (2009). Binding of epigallocatechin-3-gallate to transthyretin modulates its amyloidogenicity. FEBS Letters, 583(22), 3569 - 3576.
Leal, S. S., Cardoso, I., Valentine, J. S., & Gomes, C. M. (2013). Calcium ions promote superoxide dismutase 1 (SOD1) aggregation into non-fibrillar amyloid: A link to toxic effects of calcium overload in amyotrophic lateral sclerosis (ALS)?. Journal of Biological Chemistry, 288(35), 25219 - 25228.
Cardoso, I., Almeida, M. R., Ferreira, N., Arsequell, G., et al. (2007). Comparative in vitro and ex vivo activities of selected inhibitors of transthyretin aggregation: Relevance in drug design. Biochemical Journal, 408(1), 131 - 138.
Saraiva, A. M., Cardoso, I., Pereira, M. C., Coelho, M. A. N., et al. (2010). Controlling amyloid-β peptide(1-42) oligomerization and toxicity by fluorinated nanoparticles. ChemBioChem, 11(13), 1905 - 1913.
Rocha, S., Cardoso, I., Börner, H., Pereira, M. C., et al. (2009). Design and biological activity of β-sheet breaker peptide conjugates. Biochemical and Biophysical Research Communications, 380(2), 397 - 401.
Cardoso, I., & Saraiva, M. J. (2006). Doxycycline disrupts transthyretin amyloid: Evidence from studies in a FAP transgenic mice model. FASEB Journal, 20(2), 234 - 239.
Loureiro, J. A., Gomes, B., Fricker, G., Cardoso, I., et al. (2015). Dual ligand immunoliposomes for drug delivery to the brain. Colloids and Surfaces B: Biointerfaces, 134, 213 - 219.
Paiva, D., Martín-Molina, A., Cardoso, I., Quesada-Pérez, M., et al. (2013). The effect of a fluorinated cholesterol derivative on the stability and physical properties of cationic DNA vectors. Soft Matter, 9(2), 401 - 409.
Cardoso, I., Brito, M., & Saraiva, M. J. (2008). Extracellular matrix markers for disease progression and follow-up of therapies in familial amyloid polyneuropathy V30M TTR-related. Disease Markers, 25(1), 37 - 47.
Saraiva, M. J., Sousa, M. M., Cardoso, I., & Fernandes, R. (2004). Familial amyloidotic polyneuropathy: Protein aggregation in the peripheral nervous system. Journal of Molecular Neuroscience, 23(1-2), 35 - 40.
Oliveira, S. M., Ribeiro, C. A., Cardoso, I., & Saraiva, M. J. (2011). Gender-dependent transthyretin modulation of brain amyloid-β Levels: Evidence from a mouse model of alzheimer's disease. Journal of Alzheimer's Disease, 27(2), 429 - 439.
Martinho, A., Gonçalves, I., Cardoso, I., Almeida, M. R., et al. (2010). Human metallothioneins 2 and 3 differentially affect amyloid-beta binding by transthyretin. FEBS Journal, 277(16), 3427 - 3436.
Santos, S. D., Cardoso, I., Magalhães, J., & Saraiva, M. J. (2007). Impairment of the ubiquitin-proteasome system associated with extracellular transthyretin aggregates in familial amyloidotic polyneuropathy. Journal of Pathology, 213(2), 200 - 209.
Monteiro, F. A., Cardoso, I., Sousa, M. M., & Saraiva, M. J. (2006). In vitro inhibition of transthyretin aggregate-induced cytotoxicity by full and peptide derived forms of the soluble receptor for advanced glycation end products (RAGE). FEBS Letters, 580(14), 3451 - 3456.
Gimeno, A., Santos, L. M., Alemi, M., Rivas, J., et al. (2017). Insights on the Interaction between Transthyretin and Aβ in Solution. A Saturation Transfer Difference (STD) NMR Analysis of the Role of Iododiflunisal. Journal of Medicinal Chemistry, 60(13), 5749 - 5758.
Carvalho, S. B., Botelho, H. M., Leal, S. S., Cardoso, I., et al. (2013). Intrinsically Disordered and Aggregation Prone Regions Underlie β-Aggregation in S100 Proteins. PLoS ONE, 8(10).
Conejos-Sánchez, I., Cardoso, I., Oteo-Vives, M., Romero-Sanz, E., et al. (2015). Polymer-doxycycline conjugates as fibril disrupters: An approach towards the treatment of a rare amyloidotic disease. Journal of Controlled Release, 198, 80 - 90.
Saraiva, A. M., Cardoso, I., Saraiva, M. J., Tauer, K., et al. (2010). Randomization of Amyloid-β-Peptide(1-42) Conformation by Sulfonated and Sulfated Nanoparticles Reduces Aggregation and Cytotoxicity. Macromolecular Bioscience, 10(10), 1152 - 1163.
Santos, L. M., Rodrigues, D., Alemi, M., Silva, S. C., et al. (2016). Resveratrol administration increases transthyretin protein levels, ameliorating AD features: The importance of transthyretin tetrameric stability. Molecular Medicine, 22, 597 - 607.
Almeida, M. R., Macedo, B., Cardoso, I., Alves, I., et al. (2004). Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative. Biochemical Journal, 381(2), 351 - 356.
Cristóvão, J. S., Leal, S. S., Cardoso, I., & Gomes, C. M. (2013). Small molecules present in the cerebrospinal fluid metabolome influence superoxide dismutase 1 aggregation. International Journal of Molecular Sciences, 14(9), 19128 - 19145.
Almeida, M. R., Gales, L., Damas, A. M., Cardoso, I., & Saraiva, M. J. (2005). Small transthyretin (TTR) ligands as possible therapeutic agents in TTR amyloidoses. Current Drug Targets: CNS and Neurological Disorders, 4(5), 587 - 596.

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