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Filters: Author is Saraiva, M.J.  [Clear All Filters]
2017
Lopes, C. D. F., Gonçalves, N. P., Gomes, C. P., Saraiva, M. J., & Pêgo, A. P. (2017). BDNF gene delivery mediated by neuron-targeted nanoparticles is neuroprotective in peripheral nerve injury. Biomaterials, 121, 83 - 96.
Panayiotou, E., Fella, E., Papacharalambous, R., Malas, S., et al. (2017). C1q ablation exacerbates amyloid deposition: A study in a transgenic mouse model of ATTRV30M amyloid neuropathy. PLoS ONE, 12(4).
Sant'Anna, R., Almeida, M. R., Varejao, N., Gallego, P., et al. (2017). Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation. Scientific Reports, 7.
Gonçalves, N. P., Moreira, J., Martins, D., Vieira, P., et al. (2017). Differential expression of Cathepsin E in transthyretin amyloidosis: From neuropathology to the immune system. Journal of Neuroinflammation, 14(1).
Teixeira, C., Costelha, S., Martins, H. S., Teixeira, A., & Saraiva, M. J. (2017). Doxycycline-tauroursodeoxycholic acid treatment: effects in the heart of a transthyretin V30M transgenic mouse model. Amyloid, 24, 80.
Gonçalves, P., Martins, H., Costelha, S., & Saraiva, M. J. (2017). Efficiency of siRNA for removal of transthyretin V30M in a TTR leptomeningeal animal model. Amyloid, 24, 38 - 39.
Pires, R. H., Saraiva, M. J., Damas, A. M., & Kellermayer, M. S. Z. (2017). Force spectroscopy reveals the presence of structurally modified dimers in transthyretin amyloid annular oligomers. Journal of Molecular Recognition, 30(3).
Gonçalves, N. P., Martins, D., & Saraiva, M. J. (2017). The importance of pre-clinical studies in animal models of TTR amyloidosis for the discovery of novel patient disease biomarkers. Amyloid, 24, 83 - 84.
Martins, D., Moreira, J., Gonçalves, N. P., & Saraiva, M. J. (2017). MMP-14 overexpression correlates with the neurodegenerative process in familial amyloidotic polyneuropathy. DMM Disease Models and Mechanisms, 10(10), 1253 - 1260.
Pansieri, J., Plissonneau, M., Stransky-Heilkron, N., Dumoulin, M., et al. (2017). Multimodal imaging Gd-nanoparticles functionalized with Pittsburgh compound B or a nanobody for amyloid plaques targeting. Nanomedicine, 12(14), 1675 - 1687.
2016
Ferreira, N., Gonçalves, N. P., Saraiva, M. J., & Almeida, M. R. (2016). Curcumin: A multi-Target disease-modifying agent for late-stage transthyretin amyloidosis. Scientific Reports, 6.
Gonçalves, P., Martins, H., Costelha, S., Maia, L. F., & Saraiva, M. J. (2016). Efficiency of silencing RNA for removal of transthyretin V30M in a TTR leptomeningeal animal model. Amyloid, 23(4), 249 - 253.
Vieira, M., Leal, S. S., Gomes, C. M., & Saraiva, M. J. (2016). Evidence for synergistic action of transthyretin and IGF-I over the IGF-I receptor. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1862(4), 797 - 804.
Plissonneau, M., Pansieri, J., Heinrich-Balard, L., Morfin, J. - F., et al. (2016). Gd-nanoparticles functionalization with specific peptides for ß-amyloid plaques targeting. Journal of Nanobiotechnology, 14(1).
Teixeira, C. A., Almeida, M. D. R., & Saraiva, M. J. (2016). Impairment of autophagy by TTR V30M aggregates: In vivo reversal by TUDCA and curcumin. Clinical Science, 130(18), 1665 - 1675.
Simões, C. J. V., Almeida, Z. L., Costa, D., Jesus, C. S. H., et al. (2016). A novel bis-furan scaffold for transthyretin stabilization and amyloid inhibition. European Journal of Medicinal Chemistry, 121, 823 - 840.
Gonçalves, N. P., Martins, D., & Saraiva, M. J. (2016). Overexpression of Protocadherin-10 in Transthyretin-Related Familial Amyloidotic Polyneuropathy. American Journal of Pathology, 186(7), 1913 - 1924.
Butler, J. S., Chan, A., Costelha, S., Fishman, S., et al. (2016). Preclinical evaluation of RNAi as a treatment for transthyretin-mediated amyloidosis. Amyloid, 23(2), 109 - 118.
Gonçalves, N. P., Gonçalves, P., Magalhaes, J., Ventosa, M., et al. (2016). Tissue remodeling after interference RNA mediated knockdown of transthyretin in a familial amyloidotic polyneuropathy mouse model. Neurobiology of Aging, 47, 91 - 101.
Alemi, M., Gaiteiro, C., Ribeiro, C. A., Santos, L. M., et al. (2016). Transthyretin participates in beta-amyloid transport from the brain to the liver- involvement of the low-density lipoprotein receptor-related protein 1?. Scientific Reports, 6.
Gomes, J. R., Nogueira, R. S., Vieira, M., Santos, S. D., et al. (2016). Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemia. Cell Death and Differentiation, 23(11), 1749 - 1764.

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