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Ohmori, H., Ando, Y., Makita, Y., Onouchi, Y., et al. (2004). Common origin of the Val30Met mutation responsible for the amyloidogenic transthyretin type of familial amyloidotic polyneuropathy. Journal of medical genetics, 41(4).
Morais-De-Sá, E., Pereira, P. J. B., Saraiva, M. J., & Damas, A. M. (2004). The crystal structure of transthyretin in complex with diethylstilbestrol: A promising template for the design of amyloid inhibitors. Journal of Biological Chemistry, 279(51), 53483 - 53490.
Sousa, M. M., Ferraõ, J., Fernandes, R., Guimarães, A., et al. (2004). Deposition and passage of transthyretin through blood-nerve barrier in recipients of familial amyloid polyneuropathy livers. Laboratory Investigation, 84(7), 865 - 873.
Santos, S. D., & Saraiva, M. J. (2004). Enlarged ventricles, astrogliosis and neurodegeneration in heat shock factor 1 null mouse brain. Neuroscience, 126(3), 657 - 663.
Saraiva, M. J., Sousa, M. M., Cardoso, I., & Fernandes, R. (2004). Familial amyloidotic polyneuropathy: Protein aggregation in the peripheral nervous system. Journal of Molecular Neuroscience, 23(1-2), 35 - 40.
Soares, M. L., Coelho, T., Sousa, A., Holmgren, G., et al. (2004). Haplotypes and DNA sequence variation within and surrounding the transthyretin gene: Genotype-phenotype correlations in familial amyloid polyneuropathy (V30M) in Portugal and Sweden. European Journal of Human Genetics, 12(3), 225 - 237.
De Carvalho, M., Linke, R. P., Domingos, F., Evangelista, T., et al. (2004). Mutant fibrinogen A-α-chain associated with hereditary renal amyloidosis and peripheral neuropathy. Amyloid, 11(3), 200 - 207.
Almeida, M. R., Macedo, B., Cardoso, I., Alves, I., et al. (2004). Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative. Biochemical Journal, 381(2), 351 - 356.
Liz, M. A., Faro, C. J., Saraiva, M. J., & Sousa, M. M. (2004). Transthyretin, a new cryptic protease. Journal of Biological Chemistry, 279(20), 21431 - 21438.
Westermark, P., Benson, M. D., Buxbaum, J. N., Cohen, A. S., et al. (2005). Amyloid: Toward terminology clarification: Report from the Nomenclature Committee of the International Society Of Amyloidosis. Amyloid, 12(1), 1 - 4.
Maia, F., Almeida, M. D. R., Gales, L., Kijjoa, A., et al. (2005). The binding of xanthone derivatives to transthyretin. Biochemical Pharmacology, 70(12), 1861 - 1869.
Gales, L., Macedo-Ribeiro, S., Arsequell, G., Valencia, G., et al. (2005). Human transthyretin in complex with iododiflunisal: Structural features associated with a potent amyloid inhibitor. Biochemical Journal, 388(2), 615 - 621.
Almeida, M. R., Gales, L., Damas, A. M., Cardoso, I., & Saraiva, M. J. (2005). Small transthyretin (TTR) ligands as possible therapeutic agents in TTR amyloidoses. Current Drug Targets: CNS and Neurological Disorders, 4(5), 587 - 596.
Soares, M. L., Coelho, T., Sousa, A., Batalov, S., et al. (2005). Susceptibility and modifier genes in Portuguese transthyretin V30M amyloid polyneuropathy: Complexity in a single-gene disease. Human Molecular Genetics, 14(4), 543 - 553.
Sousa, J. C., Morreale de Escobar, G., Oliveira, P., Saraiva, M. J., & Palha, J. A. (2005). Transthyretin is not necessary for thyroid hormone metabolism in conditions of increased hormone demand. Journal of Endocrinology, 187(2), 257 - 266.
Sousa, M. M., Do Amaral, J. B., Guimarães, A., & Saraiva, M. J. (2005). Up-regulation of the extracellular matrix remodeling genes, biglycan, neutrophil gelatinase-associated lipocalin, and matrix metalloproteinase-9 in familial amyloid polyneuropathy. FASEB Journal, 19(1), 124 - 126.
Neto-Silva, R. M., Macedo-Ribeiro, S., Pereira, P. J. B., Coll, M., et al. (2005). X-ray crystallographic studies of two transthyretin variants: Further insights into amyloidogenesis. Acta Crystallographica Section D: Biological Crystallography, 61(3), 333 - 339.
Monteiro, F. A., Sousa, M. M., Cardoso, I., Do Amaral, J. B., et al. (2006). Activation of ERK1/2 MAP kinases in familial amyloidotic polyneuropathy. Journal of Neurochemistry, 97(1), 151 - 161.
Morais-De-Sá, E., Neto-Silva, R. M., Pereira, P. J. B., Saraiva, M. J., & Damas, A. M. (2006). The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin. Acta Crystallographica Section D: Biological Crystallography, 62(5), 512 - 519.
Cardoso, I., & Saraiva, M. J. (2006). Doxycycline disrupts transthyretin amyloid: Evidence from studies in a FAP transgenic mice model. FASEB Journal, 20(2), 234 - 239.
Teixeira, P. F., Cerca, F., Santos, S. D., & Saraiva, M. J. (2006). Endoplasmic reticulum stress associated with extracellular aggregates: Evidence from transthyretin deposition in familial amyloid polyneuropathy. Journal of Biological Chemistry, 281(31), 21998 - 22003.
Terazaki, H., Ando, Y., Fernandes, R., Yamamura, K. - I., et al. (2006). Immunization in familial amyloidotic polyneuropathy: Counteracting deposition by immunization with a Y78F TTR mutant. Laboratory Investigation, 86(1), 23 - 31.
Monteiro, F. A., Cardoso, I., Sousa, M. M., & Saraiva, M. J. (2006). In vitro inhibition of transthyretin aggregate-induced cytotoxicity by full and peptide derived forms of the soluble receptor for advanced glycation end products (RAGE). FEBS Letters, 580(14), 3451 - 3456.
Nunes, A. F., Saraiva, M. J., & Sousa, M. M. (2006). Transthyretin knockouts are a new mouse model for increased neuropeptide Y. FASEB Journal, 20(1), 166 - 168.


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