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Filters: Author is Saraiva, M.J.  [Clear All Filters]
2004
Ohmori, H., Ando, Y., Makita, Y., Onouchi, Y., et al. (2004). Common origin of the Val30Met mutation responsible for the amyloidogenic transthyretin type of familial amyloidotic polyneuropathy. Journal of medical genetics, 41(4).
Morais-De-Sá, E., Pereira, P. J. B., Saraiva, M. J., & Damas, A. M. (2004). The crystal structure of transthyretin in complex with diethylstilbestrol: A promising template for the design of amyloid inhibitors. Journal of Biological Chemistry, 279(51), 53483 - 53490.
Sousa, M. M., Ferraõ, J., Fernandes, R., Guimarães, A., et al. (2004). Deposition and passage of transthyretin through blood-nerve barrier in recipients of familial amyloid polyneuropathy livers. Laboratory Investigation, 84(7), 865 - 873.
Santos, S. D., & Saraiva, M. J. (2004). Enlarged ventricles, astrogliosis and neurodegeneration in heat shock factor 1 null mouse brain. Neuroscience, 126(3), 657 - 663.
Saraiva, M. J., Sousa, M. M., Cardoso, I., & Fernandes, R. (2004). Familial amyloidotic polyneuropathy: Protein aggregation in the peripheral nervous system. Journal of Molecular Neuroscience, 23(1-2), 35 - 40.
Soares, M. L., Coelho, T., Sousa, A., Holmgren, G., et al. (2004). Haplotypes and DNA sequence variation within and surrounding the transthyretin gene: Genotype-phenotype correlations in familial amyloid polyneuropathy (V30M) in Portugal and Sweden. European Journal of Human Genetics, 12(3), 225 - 237.
De Carvalho, M., Linke, R. P., Domingos, F., Evangelista, T., et al. (2004). Mutant fibrinogen A-α-chain associated with hereditary renal amyloidosis and peripheral neuropathy. Amyloid, 11(3), 200 - 207.
Almeida, M. R., Macedo, B., Cardoso, I., Alves, I., et al. (2004). Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative. Biochemical Journal, 381(2), 351 - 356.
Liz, M. A., Faro, C. J., Saraiva, M. J., & Sousa, M. M. (2004). Transthyretin, a new cryptic protease. Journal of Biological Chemistry, 279(20), 21431 - 21438.
2005
Westermark, P., Benson, M. D., Buxbaum, J. N., Cohen, A. S., et al. (2005). Amyloid: Toward terminology clarification: Report from the Nomenclature Committee of the International Society Of Amyloidosis. Amyloid, 12(1), 1 - 4.
Maia, F., Almeida, M. D. R., Gales, L., Kijjoa, A., et al. (2005). The binding of xanthone derivatives to transthyretin. Biochemical Pharmacology, 70(12), 1861 - 1869.
Gales, L., Macedo-Ribeiro, S., Arsequell, G., Valencia, G., et al. (2005). Human transthyretin in complex with iododiflunisal: Structural features associated with a potent amyloid inhibitor. Biochemical Journal, 388(2), 615 - 621.
Almeida, M. R., Gales, L., Damas, A. M., Cardoso, I., & Saraiva, M. J. (2005). Small transthyretin (TTR) ligands as possible therapeutic agents in TTR amyloidoses. Current Drug Targets: CNS and Neurological Disorders, 4(5), 587 - 596.
Soares, M. L., Coelho, T., Sousa, A., Batalov, S., et al. (2005). Susceptibility and modifier genes in Portuguese transthyretin V30M amyloid polyneuropathy: Complexity in a single-gene disease. Human Molecular Genetics, 14(4), 543 - 553.
Sousa, J. C., Morreale de Escobar, G., Oliveira, P., Saraiva, M. J., & Palha, J. A. (2005). Transthyretin is not necessary for thyroid hormone metabolism in conditions of increased hormone demand. Journal of Endocrinology, 187(2), 257 - 266.
Sousa, M. M., Do Amaral, J. B., Guimarães, A., & Saraiva, M. J. (2005). Up-regulation of the extracellular matrix remodeling genes, biglycan, neutrophil gelatinase-associated lipocalin, and matrix metalloproteinase-9 in familial amyloid polyneuropathy. FASEB Journal, 19(1), 124 - 126.
Neto-Silva, R. M., Macedo-Ribeiro, S., Pereira, P. J. B., Coll, M., et al. (2005). X-ray crystallographic studies of two transthyretin variants: Further insights into amyloidogenesis. Acta Crystallographica Section D: Biological Crystallography, 61(3), 333 - 339.
2006
Monteiro, F. A., Sousa, M. M., Cardoso, I., Do Amaral, J. B., et al. (2006). Activation of ERK1/2 MAP kinases in familial amyloidotic polyneuropathy. Journal of Neurochemistry, 97(1), 151 - 161.
Morais-De-Sá, E., Neto-Silva, R. M., Pereira, P. J. B., Saraiva, M. J., & Damas, A. M. (2006). The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin. Acta Crystallographica Section D: Biological Crystallography, 62(5), 512 - 519.
Cardoso, I., & Saraiva, M. J. (2006). Doxycycline disrupts transthyretin amyloid: Evidence from studies in a FAP transgenic mice model. FASEB Journal, 20(2), 234 - 239.
Teixeira, P. F., Cerca, F., Santos, S. D., & Saraiva, M. J. (2006). Endoplasmic reticulum stress associated with extracellular aggregates: Evidence from transthyretin deposition in familial amyloid polyneuropathy. Journal of Biological Chemistry, 281(31), 21998 - 22003.
Terazaki, H., Ando, Y., Fernandes, R., Yamamura, K. - I., et al. (2006). Immunization in familial amyloidotic polyneuropathy: Counteracting deposition by immunization with a Y78F TTR mutant. Laboratory Investigation, 86(1), 23 - 31.
Monteiro, F. A., Cardoso, I., Sousa, M. M., & Saraiva, M. J. (2006). In vitro inhibition of transthyretin aggregate-induced cytotoxicity by full and peptide derived forms of the soluble receptor for advanced glycation end products (RAGE). FEBS Letters, 580(14), 3451 - 3456.
Nunes, A. F., Saraiva, M. J., & Sousa, M. M. (2006). Transthyretin knockouts are a new mouse model for increased neuropeptide Y. FASEB Journal, 20(1), 166 - 168.

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