TUESDAY | OCTOBER 6TH |
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| 11:30-14:00 | Registration | |
| 14:00-14:10 | Welcome address | Silvio Tosatto & Sandra Macedo-Ribeiro | |
| 14:10-15:00 | PLENARY LECTURE | Chair: Silvio Tosatto | |
| Chair: Silvio Tosatto | ||
| Odd Biophysics of Intrinsic Disorder | ||
| Vladimir Uversky | USF, USA | ||
| 15:10-16:00 | Flash posters | |
| 16:00-16:40 | Coffee Break | |
| 16:40-18:20 | SESSION I | Chairs: Sandra Macedo-Ribeiro & Sonia Longhi | |
| 16:40-17:10 | Protein repeats: From sequence to structure and function | |
| Andrey Kajava | CNRS, France | ||
| 17:10-17:40 | Function of PolyQ repeats in protein interactions | |
| Miguel Andrade | JGU/IMB, Mainz, Germany | ||
| 17:40-18:00 | TAAs: rigid, fibrous adhesins on the bacterial cell surface | |
| Dirk Linke | MPI for Developmental Biology, Germany | ||
| 18:00-18:20 | Repeat proteins as scaffolds for nanotechnology | |
| Aitziber L. Cortajarena | IMDEA Nanociencia, Spain | ||
| 18:30-20:00 | COST ACTION BM1405 Core Group Meeting (closed) | |
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WEDNESDAY | OCTOBER 7TH |
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| 9:00-11:00 | SESSION II | Chair: Marco Punta & Zsuzsanna Dosztanyi | |
| 9:00-9:30 | Non-globular proteins: Towards an understanding of the "dark matter" in the protein universe |
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| Silvio Tosatto | University of Padua, Italy | ||
| 9:30-10:00 | Muscle proteins: 'perfect' examples of non globular proteins | |
| Annalisa Pastore | King's College London, UK | ||
| 10:00-10:20 | Multi-level machine learning prediction of protein-protein interactions | |
| Julian Zubek & Dariusz Plewczynski | Centre of New Technologies, University of Warsaw, Poland |
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| 10:20-10:40 | Relation between early folding, dynamics and conformation in proteins | |
| Wim Vranken | VIB and Vrije Universiteit Brussel, Belgium | ||
| 10:40-11:00 | ITRANS database - sorting structural motifs in cellular transporters | |
| Afonso Duarte | ITQB, Portugal | ||
| 11:00-11:30 | Coffee Break | |
| 11:30-13:10 | SESSION III | Chairs: Miguel Andrade & Annalisa Pastore | |
| 11:30-12:00 | Finding functional regions within intrinsically disordered proteins | |
| Zsuzsanna Dosztànyi | Eotvos Lorand University, Hungary | ||
| 12:00-12:30 | Intrinsically disordered protein families | |
| Marco Punta | University Pierre and Marie Curie, France | ||
| 12:30-12:50 |
Intrinsically Disordered Proteins /Protein Regions: Implications for Environmental Adaptation of Archaea and Bacteria |
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| Gordana Pavlovic-Lazetic | University of Belgrade, Serbia | ||
| 12:50-13:10 |
Large-scale analysis of protein conformational diversity and intrinsic disorder suggests the existence of three main structure-function relationships |
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| Gustavo Parisi | Universidad Nacional de Quilmes, Argentina | ||
| 13:10-14:00 | Lunch | |
| 14:00-15:00 | POSTER SESSION I | |
| 15:00-17:00 | SESSION IV | Chairs: Andrey Kajava & Gian Tartaglia | |
| 15:00-15:30 | What makes a protein sequence prionic? | |
| Salvador Ventura | UAB, Spain | ||
| 15:30-16:00 | De novo design of biologically active amyloids | |
| Frederic Rousseau | VIB, Belgium | ||
| 16:00-16:20 |
What can the kinetics of amyloid fibril formation tell us about off-pathway aggregation? |
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| Pedro M. Martins | University of Porto, Portugal | ||
| 16:20-16:40 | pH-driven polymorphism of insulin amyloid-like fibrils | |
| Vytautas Smirnovas | Vilnius University Institute of Biotechnology, Lithuania | ||
| 16:40-17:00 |
Influence of Homo-Repeats and Repeats on Functions and Aggregation Propensities of Protein Chains |
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| Galzitskaya Oxana | Institute of Protein Research, Russia | ||
| 17:00-17:30 | Coffee Break | |
| 17:30-18:30 | Flash posters | |
| 20:30 | Social Dinner | |
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THURSDAY OCTOBER 8TH |
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| 9:00-11:00 | SESSION V | Chairs: Toby Gibson & Frederic Rousseau | |
| 9:00-9:30 | The tripartite degron model: The role of structural disorder in protein quality control | |
| Peter Tompa | VIB, Belgium | ||
| 9:30-10:00 | Combinatorial and Evolutionary Protein Engineering | |
| Andreas Plükthun | Zurich University, Switzerland | ||
| 10:00-10:20 | A Bio-NMR View of the Conformational Ensemble of Intrinsically Disordered WIP | |
| Jordan Chill | Bar Ilan University, Israel | ||
| 10:20-10:40 | What drives coupled folding and strong binding of an α-helix-forming MoRF? | |
| Jurij Lah | University of Ljubljana, Slovenia | ||
| 10:40-11:00 |
The AMSH/SH3 complex as an example of the interaction between a multi-domain protein and an unstructured peptide |
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| Maggy Hologne | Université de Lyon, France | ||
| 11:00-11:30 | Coffee Break | |
| 11:30-13:00 | SESSION VI | Chairs: Andreas Plückthun & Peter Tompa | |
| 11:30-12:00 | Mechanisms of partner recognition by intrinsically disordered proteins | |
| Sonia Longhi | CNRS and Aix-Marseille University, France | ||
| 12:00-12:30 | Fuzzy complexes and their biological functions | |
| Mónika Fuxtreiter | University of Debrecen, Hungary | ||
| 12:30-12:50 |
Conformational changes governing dengue virus capsid protein disordered N-terminal region and its inhibition by pep14-23 |
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| André F. Faustino | IMM, Portugal | ||
| 12:50-13:10 | The Nature and role of stress-regulated protein disorder in cellular proteostasis | |
| Dana Reichmann | The Hebrew University of Jerusalem, Israel | ||
| 13:10-14:00 | Lunch | |
| 14:00-15:00 | POSTER SESSION II | |
| 15:00-16:30 | Round Table Discussion | |
| 16:30-17:00 | Coffee Break | |
| 16:30-18:00 | COST ACTION BM1405 MC Meeting (open) | |
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FRIDAY | OCTOBER 9TH |
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| 09:00-11:00 | SESSION VII | Chairs: Mónika Fuxreiter & Silvio Tosatto | |
| 09:00-09:30 | Function, regulation and evolution of proteins with homorepeats | |
| Sreenivas Chavali | MRC Laboratory of Molecular Biology, UK | ||
| 09:30-10:00 | Detecting, validating and cataloguing short linear motifs | |
| Toby Gibson | EMBL, Germany | ||
| 10:00-10:20 |
Disentangling tandem repeats and their evolutionary histories using statistical prediction |
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| Maria Anisimova | Zürich University of Applied Sciences, Switzerland | ||
| 10:20-10:40 | Studying local compositional bias in protein sequences: novel tools and methods and biological applications |
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| Vasilis J. Promponas | University of Cyprus, Cyprus | ||
| 10:40-11:00 |
The TOPCONS web server for consensus prediction of membrane protein topologyand signal peptides |
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| Konstantinos Tsirigos | Stockholm University, Sweden | ||
| 11:00-11:30 | Coffee Break | |
| 11:30- 12:50 | SESSION VIII | Chairs: Sreenivas Chavali & Salvador Ventura | |
| 11:30-12:00 | Structural Disorder and Aggregation of RNA-binding Proteins | |
| Gian G. Tartaglia | CRG, Barcelona, Spain | ||
| 12:00-12:30 | Polyglutamine proteins: More than simple repeats | |
| Sandra Macedo-Ribeiro | IBMC/i3S, Portugal | ||
| 12:30-12:50 |
Prediction of amyloid aggregating sequences and hot-spots: Can one predict co-aggregating proteins? |
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| Antonio Trovato | Padova University, Italy | ||
| 12:50-13:00 | Poster Awards and Closing Session | Sandra Macedo-Ribeiro & Silvio Tosatto | |