Morais-de-Sá, Eurico Research Interest Shaping the tissues that form an organism requires a tight coordination between cell division and polarity mechanisms that spatially distribute signaling cues and adhesive structures within single cells.

We aim to understand the link between the regulation of cell division and the organization of polarity at the tissue level, and to address the interplay between these processes in tumorigenesis.

Projects as Principal Investigator
Fundação para a Ciência e Tecnologia, Portugal, PTDC/BIA-BCM/120132/2010: Understanding the coordination between mitosis and cell polarity

Supervision
Cátia Mendes (BI fellow)

References
Takeo S, Lake CM, Morais-de-Sá E, Sunkel CE, Hawley RS. Synaptonemal complex-dependent centromeric clustering and the initiation of synapsis in Drosophila oocytes. Curr Biol (2011) vol. 21 (21) pp. 1845-
Morais-de-Sá E, Mirouse V, St Johnston, D. aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells. Cell (2010) vol. 141 (3) pp. 509-23