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Journal Article
da Costa Tavares, J. A. P., Ouaissi, A., & Cordeiro-da-Silva, A. (2008). Therapy and further development of anti-leishmanial drugs. Current Drug Therapy, 3(3), 204 - 208.
Vergnes, B., Sereno, D., Tavares, J., Cordeiro-da-Silva, A., et al. (2005). Targeted disruption of cytosolic SIR2 deacetylase discloses its essential role in Leishmania survival and proliferation. Gene, 363(1-2), 85 - 96.
Kadam, R. U., Tavares, J., M, K. V., Cordeiro, A., et al. (2008). Structure function analysis of Leishmania sirtuin: An ensemble of in silico and biochemical studies. Chemical Biology and Drug Design, 71(5), 501 - 506.
Silvestre, R., Cordeiro-da-Silva, A., Santarém, N., Vergnes, B., et al. (2007). SIR2-deficient Leishmania infantum induces a defined IFN-γ/IL-10 pattern that correlates with protection. Journal of Immunology, 179(5), 3161 - 3170.
Mathieu-Daudé, F., Bosseno, M. - F., Garzon, E., Lelièvre, J., et al. (2007). Sequence diversity and differential expression of Tc52 immuno-regulatory protein in Trypanosoma cruzi: Potential implications in the biological variability of strains. Parasitology Research, 101(5), 1355 - 1363.
Ouaissi, A. (2007). Regulatory cells and immunosuppressive cytokines: Parasite-derived factors induce immune polarization. Journal of Biomedicine and Biotechnology, 2007.
Ouassi, M., Giger, U., Sielezneff, I., Pirr, N., et al. (2011). Rationale for possible targeting of histone deacetylase signaling in cancer diseases with a special reference to pancreatic cancer. Journal of Biomedicine and Biotechnology, 2011.
Adriano, M. - A., Vergnes, B., Poncet, J., Mathieu-Daude, F., et al. (2007). Proof of interaction between Leishmania SIR2RP1 deacetylase and chaperone HSP83. Parasitology Research, 100(4), 811 - 818.
Rodrigues, V., Cordeiro-da-Silva, A., Laforge, M., Ouaissi, A., et al. (2012). Modulation of mammalian apoptotic pathways by intracellular protozoan parasites. Cellular Microbiology, 14(3), 325 - 333.
Sereno, D., Vergnes, B., Mathieu-Daude, F., Cordeiro Da Silva, A., & Ouaissi, A. (2006). Looking for putative functions of the Leishmania cytosolic SIR2 deacetylase. Parasitology Research, 100(1), 1 - 9.
Silvestre, R., Cordeiro-da-Silva, A., & Ouaissi, A. (2008). Live attenuated Leishmania vaccines: A potential strategic alternative. Archivum Immunologiae et Therapiae Experimentalis, 56(2), 123 - 126.
Gazanion, E., Garcia, D., Silvestre, R., Gérard, C., et al. (2011). The Leishmania nicotinamidase is essential for NAD + production and parasite proliferation. Molecular Microbiology, 82(1), 21 - 38.
Tavares, J., Ouaissi, A., Santarém, N., Sereno, D., et al. (2008). The Leishmania infantum cytosolic SIR2-related protein 1 (LiSIR2RP1) is an NAD+-dependent deacetylase and ADP-ribosyltransferase. Biochemical Journal, 415(3), 377 - 386.
Silvestre, R., Cordeiro-da-Silva, A., Tavares, J., Sereno, D., & Ouaissi, A. (2006). Leishmania cytosolic silent information regulatory protein 2 deacetylase induces murine B-cell differentiation and in vivo production of specific antibodies. Immunology, 119(4), 529 - 540.
Sereno, D., Monte Alegre, A., Silvestre, R., Vergnes, B., & Ouaissi, A. (2005). In vitro antileishmanial activity of nicotinamide. Antimicrobial Agents and Chemotherapy, 49(2), 808 - 812.
Lin, P. K. T., Hoskins, C., Ouaissi, M., Lima, S. C., et al. (2010). In vitro and in vivo anticancer activity of a novel nano-sized formulation based on self-assembling polymers against pancreatic cancer. Pharmaceutical Research, 27(12), 2694 - 2703.
Moreira, D., Santarém, N., Loureiro, I., Tavares, J., et al. (2012). Impact of continuous axenic cultivation in Leishmania infantum virulence. PLoS Neglected Tropical Diseases, 6(1).
Ouaissi, A. (2007). Immunology and molecular biology of protozoan infections. Journal of Biomedicine and Biotechnology, 2007.
Cordeiro-da-Silva, A., Tavares, J., Araújo, N., Cerqueira, F., et al. (2004). Immunological alterations induced by polyamine derivatives on murine splenocytes and human mononuclear cells. International Immunopharmacology, 4(4), 547 - 556.
Ouaissi, A., Ouaissi, M., Tavares, J., & Cordeiro-da-Silva, A. (2004). Host cell phenotypic variability induced by trypanosomatid-parasite- released immunomodulatory factors: Physiopathological implications. Journal of Biomedicine and Biotechnology, 2004(3), 167 - 174.
Ouaïssi, M., Cabral, S., Tavares, J., Cordeiro Da Silva, A., et al. (2008). Histone deacetylase (HDAC) encoding gene expression in pancreatic cancer cell lines and cell sensitivity to HDAC inhibitors. Cancer Biology and Therapy, 7(4), 523 - 531.
Ouaïssi, M., Sielezneff, I., Silvestre, R., Sastre, B., et al. (2008). High histone deacetylase 7 (HDAC7) expression is significantly associated with adenocarcinomas of the pancreas. Annals of Surgical Oncology, 15(8), 2318 - 2328.
Ouaissi, A. (2007). Functional genomics and immunological approaches toward a comprehensive view of protozoan parasite virulence factors. Expert Review of Anti-Infective Therapy, 5(4), 535 - 538.
Mathieu-Daudé, F., Lafay, B., Touzet, O., Lelièvre, J., et al. (2008). Exploring the FL-160-CRP gene family through sequence variability of the complement regulatory protein (CRP) expressed by the trypomastigote stage of Trypanosoma cruzi. Infection, Genetics and Evolution, 8(3), 258 - 266.
Tavares, J., Ouaissi, A., Lin, P. K. T., Tomás, A., & Cordeiro-da-Silva, A. (2005). Differential effects of polyamine derivative compounds against Leishmania infantum promastigotes and axenic amastigotes. International Journal for Parasitology, 35(6), 637 - 646.


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