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Author Title [ Type(Desc)] Year
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Journal Article
Teixeira, A. C., & Saraiva, M. J. (2013). Presence of N-glycosylated transthyretin in plasma of V30M carriers in familial amyloidotic polyneuropathy: An escape from ERAD. Journal of Cellular and Molecular Medicine, 17(3), 429 - 435.
Westermark, P., Benson, M. D., Buxbaum, J. N., Cohen, A. S., et al. (2007). A primer of amyloid nomenclature. Amyloid, 14(3), 179 - 183.
Quintela, T., Gonçalves, I., Martinho, A., Alves, C. H., et al. (2011). Progesterone enhances transthyretin expression in the rat choroid plexus in vitro and in vivo via progesterone receptor. Journal of Molecular Neuroscience, 44(3), 152 - 158.
Gonçalves, N. P., Teixeira-Coelho, M., & Saraiva, M. J. (2015). Protective role of anakinra against transthyretin-mediated axonal loss and cell death in a mouse model of familial amyloidotic polyneuropathy. Journal of Neuropathology and Experimental Neurology, 74(3), 203 - 217.
Saraiva, A. M., Cardoso, I., Saraiva, M. J., Tauer, K., et al. (2010). Randomization of Amyloid-β-Peptide(1-42) Conformation by Sulfonated and Sulfated Nanoparticles Reduces Aggregation and Cytotoxicity. Macromolecular Bioscience, 10(10), 1152 - 1163.
Almeida, M. R., Macedo, B., Cardoso, I., Alves, I., et al. (2004). Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative. Biochemical Journal, 381(2), 351 - 356.
Almeida, M. R., Gales, L., Damas, A. M., Cardoso, I., & Saraiva, M. J. (2005). Small transthyretin (TTR) ligands as possible therapeutic agents in TTR amyloidoses. Current Drug Targets: CNS and Neurological Disorders, 4(5), 587 - 596.
Sárkány, Z., Ikonen, T. P., Ferreira-Da-Silva, F., Saraiva, M. J., et al. (2011). Solution structure of the soluble receptor for advanced glycation end products (sRAGE). Journal of Biological Chemistry, 286(43), 37525 - 37534.
Ribeiro, C. A., Saraiva, M. J., & Cardoso, I. (2012). Stability of the Transthyretin Molecule as a Key Factor in the Interaction with A-Beta Peptide - Relevance in Alzheimer's Disease. PLoS ONE, 7(9).
Gales, L., Saraiva, M. J., & Damas, A. M. (2007). Structural basis for the protective role of sulfite against transthyretin amyloid formation. Biochimica et Biophysica Acta - Proteins and Proteomics, 1774(1), 59 - 64.
Castro-Rodrigues, A. F., Gales, L., Saraiva, M. J., & Damas, A. M. (2011). Structural insights into a zinc-dependent pathway leading to Leu55Pro transthyretin amyloid fibrils. Acta Crystallographica Section D: Biological Crystallography, 67(12), 1035 - 1044.
Pires, R. H., Saraiva, M. J., Damas, A. M., & Kellermayer, M. S. Z. (2011). Structure and assembly-disassembly properties of wild-type transthyretin amyloid protofibrils observed with atomic force microscopy. Journal of Molecular Recognition, 24(3), 467 - 476.
Niederhauser, J., Lobrinus, J. A., Ochsner, F., Wider, C., et al. (2011). Successful heart and liver transplantation in a swiss patient with glu89lys transthyretin amyloidosis. Transplantation, 91(6), e40 - e42.
Soares, M. L., Coelho, T., Sousa, A., Batalov, S., et al. (2005). Susceptibility and modifier genes in Portuguese transthyretin V30M amyloid polyneuropathy: Complexity in a single-gene disease. Human Molecular Genetics, 14(4), 543 - 553.
Cardoso, I., Martins, D., Ribeiro, T., Merlini, G., & Saraiva, M. J. (2010). Synergy of combined Doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: Studies in FAP mouse models. Journal of Translational Medicine, 8.
Conejos-Sánchez, I., Cardoso, I., Saraiva, M. J., & Vicent, M. J. (2014). Targeting a rare amyloidotic disease through rationally designed polymer conjugates. Journal of Controlled Release, 178(1), 95 - 100.
Gonçalves, N. P., Gonçalves, P., Magalhaes, J., Ventosa, M., et al. (2016). Tissue remodeling after interference RNA mediated knockdown of transthyretin in a familial amyloidotic polyneuropathy mouse model. Neurobiology of Aging, 47, 91 - 101.
Vieira, M., & Saraiva, M. J. (2014). Transthyretin: A multifaceted protein. Biomolecular Concepts, 5(1), 45 - 54.
Liz, M. A., Faro, C. J., Saraiva, M. J., & Sousa, M. M. (2004). Transthyretin, a new cryptic protease. Journal of Biological Chemistry, 279(20), 21431 - 21438.
Sousa, J. C., Cardoso, I., Marques, F., Saraiva, M. J., & Palha, J. A. (2007). Transthyretin and Alzheimer's disease: Where in the brain?. Neurobiology of Aging, 28(5), 713 - 718.
Costa, R., Gonçalves, A., Saraiva, M. J., & Cardoso, I. (2008). Transthyretin binding to A-Beta peptide - Impact on A-Beta fibrillogenesis and toxicity. FEBS Letters, 582(6), 936 - 942.
Ribeiro, C. A., Santana, I., Oliveira, C., Baldeiras, I., et al. (2012). Transthyretin decrease in plasma of MCI and AD patients: Investigation of mechanisms for disease modulation. Current Alzheimer Research, 9(8), 881 - 889.
Saraiva, M. J., Magalhaes, J., Ferreira, N., & Almeida, M. R. (2012). Transthyretin deposition in familial amyloidotic polyneuropathy. Current Medicinal Chemistry, 19(15), 2304 - 2311.
Fleming, C. E., Saraiva, M. J., & Sousa, M. M. (2007). Transthyretin enhances nerve regeneration. Journal of Neurochemistry, 103(2), 831 - 839.
Vieira, M., Gomes, J. R., & Saraiva, M. J. (2015). Transthyretin Induces Insulin-like Growth Factor I Nuclear Translocation Regulating Its Levels in the Hippocampus. Molecular Neurobiology, 51(3), 1468 - 1479.

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